Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT04591587Enrolling by invitation
Corneal lenticule implant for keratoconus
This trial tests a new surgical procedure using a small piece of corneal tissue (a lenticule) from a donor to strengthen the cornea in people with progressive keratoconus. The goal is to help stop the disease from getting worse.
PristinaAges 20–40 - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT07729982Recruiting
Study tracking vision changes in OPA1 optic atrophy
This study follows people with a genetic form of optic atrophy over time to understand how vision changes. It does not test a treatment but helps doctors learn more about the condition to improve care.
Munich, BavariaAges Any age - NCT07731984Recruiting
Comparing two eye measurement methods in silicone oil eyes
This study compares two ways to measure eye length in people having surgery for retinal detachment with silicone oil. The goal is to find out which measurement method works better for eyes filled with silicone oil.
SohagAges 18–70 - NCT07682896RecruitingPhase 2
Testing YB-101 for safety and effectiveness in Graves' disease
This trial tests an investigational drug called YB-101 for people with Graves' disease, whether or not they have thyroid eye disease. The goal is to see if the drug is safe and can help.
Gilbert, ArizonaAges 18 years+ - NCT07547670Recruiting
Brain Stimulation for Lazy Eye in Children
This study tests whether a non-invasive brain stimulation technique called tDCS (transcranial direct current stimulation) can help children with lazy eye (amblyopia) whose vision hasn't improved with traditional patching treatments. The goal is to see if stimulating the brain can boost the weak eye's vision.
MurciaAges 4–14 - NCT07453212Enrolling by invitation
Food supplement for dry eye caused by meibomian gland issues
This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.
IstanbulAges 18–65 - NCT07286006Enrolling by invitationPhase 2
Long-term safety study of IMVT-1402 for Graves' disease
This study is a long-term extension for people with Graves' disease who already completed a previous study with the drug IMVT-1402. It aims to see how safe and effective the drug is over a longer period.
Phoenix, ArizonaAges 18 years+ - NCT07509229Enrolling by invitationPhase 1/Phase 2
Algae Extract for Retinitis Pigmentosa
This study tests an extract from a type of algae that is rich in a special form of vitamin A. It may help improve vision for people with retinitis pigmentosa caused by certain gene mutations that affect how the eye processes vitamin A.
Tel LitwinskyAges 18 years+ - NCT07367282RecruitingPhase 4
Faricimab for newly diagnosed wet age-related macular degeneration
This study tests if faricimab, an injectable eye medication, can improve vision in people with a newly diagnosed form of wet age-related macular degeneration (AMD). It is for patients who have not yet received treatment for this condition.
SeongnamAges 50 years+ - NCT07547995RecruitingPhase 2
A study of a new drug for active uveitis
This study tests a new drug (GenSci048) for people with active, non-infectious uveitis in the middle or back of the eye, who are already taking oral steroids. The goal is to see if the drug can better control inflammation and reduce the need for steroids.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT07721779Recruiting
Steam mask vs. warm compresses for kids' eyelid lumps
This trial tests whether a special steam mask helps treat chalazion (a small lump on the eyelid) in children, compared to the usual warm compress. It's a simple home treatment that may be easier and more effective for kids.
SheffieldAges 5–16 - NCT07722910Recruiting
Iris blood flow in diabetic neovascular glaucoma
This study uses a special camera (OCTA) to look at blood flow in the iris of people with or without type 2 diabetes and diabetic neovascular glaucoma. The goal is to understand how blood flow changes in this eye condition.
Jinan, ShandongAges 18 years+ - NCT07316998Recruiting
Myopia study for healthy young children
This study follows children with normal vision to see who develops nearsightedness (myopia) and what factors might affect it. It aims to understand how eye development and environment together influence the need for glasses.
ParisAges 4–8 - NCT05079399Recruiting
Diabetic eye screening study using eye scans
This study looks for specific eye findings (“biomarkers”) in people with type 2 diabetes using eye imaging. It may help researchers better understand diabetic retinopathy and how to detect it earlier or more accurately.
Carmel, IndianaAges 18 years+ - NCT07610226Recruiting
Cataract Surgery Lens for Prior Myopic Eye Surgery
This study tests a special intraocular lens (an artificial lens implanted during cataract surgery) designed for patients who had prior myopic refractive surgery (LASIK or PRK to correct nearsightedness). The goal is to achieve the best possible vision correction after cataract removal.
Greensboro, North CarolinaAges 18 years+ - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT06371417RecruitingPhase 1
Testing RAY121 for several immune diseases (RAINBOW trial)
This trial tests a new medicine called RAY121 (an antibody) for people with certain autoimmune diseases. It aims to see if RAY121 is safe and how the body handles it. If you have one of these conditions and meet the basic health requirements, you might be able to join.
Orange, CaliforniaAges 18–85 - NCT07712939RecruitingPhase 1
Study of CND319 for rheumatic diseases
This study tests a new drug called CND319 in healthy volunteers and people with rheumatoid arthritis or Sjögren's disease. The goal is to see if it is safe and how the body responds to it.
Melbourne, VictoriaAges 18–65 - NCT07471295RecruitingPhase 4
Study of a toric lens for cataract with astigmatism
This study tests a special lens implant (toric lens) for people having cataract surgery who also have astigmatism. The lens corrects both the cataract and the astigmatism, potentially giving you clearer distance vision without glasses.
Prague, PragueAges 18 years+ - NCT03546387Recruiting
Anesthesia and brain thinking changes in children with retinoblastoma
This study looks at whether having anesthesia more than once (for eye/surgery treatment) affects children’s thinking and learning. It may help doctors plan safer care and better follow-up for children with retinoblastoma.
New York, New YorkAges 6–17 - NCT07715864RecruitingPhase 2
Cannabis compounds for brain protection after concussion
This trial tests whether natural cannabis compounds can help protect the brain after a concussion in male contact-sport athletes. It requires you to be healthy, not a regular cannabis user, and free of certain medical conditions.
Regina, SaskatchewanAges 19–35 - NCT07716397Recruiting
MRI study for thyroid eye disease diagnosis and care
This study uses MRI scans of the eye area to better understand and classify thyroid eye disease (TED). It aims to help doctors predict outcomes and personalize treatment. You may be eligible if you have stable TED or are a healthy volunteer.
Shanghai, Huangpu DistrictAges 18–75
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.