Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07561398RecruitingPhase 4
Insulin drops vs amniotic membrane for stubborn corneal sores
This trial compares two treatments for persistent corneal surface wounds that haven't healed with standard care. You'll receive either insulin eye drops or a special tissue graft to help your cornea heal.
Rawalpindi, Punjab ProvinceAges 16–70 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07567833RecruitingPhase 4
Tracking Eye Function After Diabetes Swelling Treatment
This study follows patients with diabetic eye swelling (a complication of diabetes affecting the macula, the part of your eye needed for detailed vision) who are receiving anti-VEGF injections—a standard treatment that reduces abnormal blood vessel growth. Researchers will measure how well your retina (the light-sensitive tissue in your eye) recovers and functions over time.
Augusta, GeorgiaAges 18 years+ - NCT07566975Recruiting
How VEVYE Helps Dry Eye in Neuro-Eye Patients
This study tracks whether VEVYE®, a prescription eye drop, reduces dry eye symptoms and signs in people who have both a neuro-ophthalmic condition (a nerve or brain issue affecting the eyes) and dry eye disease. You'll visit the clinic for 6 months and answer questions about your eye comfort.
Houston, TexasAges 18 years+ - NCT07561450RecruitingPhase 4
Treating eyelid mites in scleral lens wearers
This study tests a medicated eye drop (lotilaner) to treat eyelid mite inflammation (Demodex blepharitis) in people who wear PROSE scleral lenses. It aims to see if the drops safely reduce symptoms like redness, itching, and blurry vision.
Needham, MassachusettsAges 18 years+ - NCT07567040RecruitingPhase 3
Delaying Nearsightedness Onset in Children
This study tests whether low-dose atropine eye drops can prevent or slow down nearsightedness in children ages 6–11 who don't yet need glasses. The goal is to keep children's vision stable and reduce their need for corrective lenses as they grow.
Birmingham, AlabamaAges 6–11 - NCT07554911Recruiting
Improving Treatment for Severe Dry Eye Disease
This study helps doctors find better ways to treat severe dry eye disease. Researchers will perform eye exams and ask questions to understand your condition better and optimize your care.
SingaporeAges 21–99 - NCT07555574Recruiting
New imaging technology to see retinal structures clearly
This research study tests a new camera technology that takes detailed pictures of the back of your eye (retina) to better understand eye diseases. Researchers want to compare images from people with eye conditions like diabetes-related eye disease, glaucoma, or age-related macular degeneration with healthy volunteers to see how the new imaging works.
Melbourne, VictoriaAges 18 years+ - NCT07556406Recruiting
Eye imaging study for age-related macular degeneration
This study uses specialized eye imaging to track changes in geographic atrophy, a type of vision loss from macular degeneration. Researchers will use new imaging techniques to better understand how this condition progresses and how treatments work.
San Francisco, CaliforniaAges 55 years+ - NCT07559292Enrolling by invitation
AI screening to catch diabetes eye problems early
This study tests whether artificial intelligence can help detect early signs of diabetes-related eye damage before vision loss happens. You'd be screened at your regular doctor visit using a new AI tool, which could catch problems earlier than usual.
Madison, WisconsinAges 22 years+ - NCT07553455Enrolling by invitationPhase 4
Vevye plus Flarex eye drops for moderate to severe dry eye
This study tests a combination of two eye drop medications (Vevye and Flarex) to see if they work better together for treating moderate to severe dry eye. If you have persistent dry eye that hasn't improved with other treatments, this trial might help you and advance treatment options.
Azusa, CaliforniaAges 18 years+ - NCT07556133Recruiting
Comparing two sedation medicines during cataract surgery
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
BeirutAges 18 years+ - NCT07553429RecruitingPhase 1/Phase 2
Testing a new eye injection for diabetic swelling
This study tests different doses of a new medicine (BI 3812465) injected into the eye to treat diabetic macular edema—swelling in the back of the eye caused by diabetes that can blur vision. The trial measures how safe the medicine is and how well patients tolerate it.
Phoenix, ArizonaAges 18 years+ - NCT07557420RecruitingPhase 3
Ravulizumab for Neuromyelitis Optica Spectrum Disorder in Chinese Adults
This study tests a new medicine called ravulizumab (an infusion) to reduce relapses in people with neuromyelitis optica spectrum disorder (NMOSD), a rare condition affecting the optic nerve and spinal cord. The trial is specifically enrolling adults in China who have had recent disease activity.
BeijingAges 18–130 - NCT07552012RecruitingPhase 2
FXS5626 for Non-Infectious Eye Inflammation
This trial tests a new drug called FXS5626 to treat non-infectious uveitis—inflammation inside the eye that doesn't come from infection. The study looks at whether this drug can reduce eye inflammation and improve vision in people whose condition isn't controlled with steroid eye drops and oral steroids alone.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07559188Recruiting
A contact lens for presbyopia and keratoconus
This trial tests a special contact lens that uses a tiny opening to improve vision for people with presbyopia (age-related reading blur) or with keratoconus (a cone-shaped cornea). The lens aims to make both near and distant objects clearer without surgery.
AntwerpAges 18 years+ - NCT06694259Recruiting
Laser vs. freezing for retinal detachment repair
This trial compares two methods (laser or freezing) to seal tears in the retina after a procedure to reattach it. It may help people with a specific type of retinal detachment where the tear is in the upper part of the eye.
SplitAges 18 years+ - NCT07548944Recruiting
How Electrical Stimulation Affects Your Vision
This study watches how a treatment called transcorneal electrical stimulation (TES)—which uses gentle electrical pulses on your eye—affects your vision in the short term. You'll be observed while using the OkuStim device, and researchers will ask about any improvements you notice in your sight.
Frankfurt am MainAges 18 years+ - NCT07547995RecruitingPhase 2
A study of a new drug for active uveitis
This study tests a new drug (GenSci048) for people with active, non-infectious uveitis in the middle or back of the eye, who are already taking oral steroids. The goal is to see if the drug can better control inflammation and reduce the need for steroids.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07547228RecruitingPhase 1/Phase 2
PRL3-zumab for advanced age-related macular degeneration
This study tests a new injectable medicine called PRL3-zumab for patients with advanced wet macular degeneration (nAMD) whose condition hasn't improved enough with standard treatments. The goal is to see if this new approach can help preserve or improve vision in people who have already tried at least two other eye injections.
SingaporeAges 18 years+ - NCT07550907Recruiting
Cataract Surgery Outcomes and Surgical Technique Study
This study examines how different surgical approaches during cataract removal affect your vision and eye health after surgery. If you need cataract surgery, this trial may help doctors understand which techniques work best for patients like you.
Guangzhou, GuangdongAges 50–90 - NCT07550777Recruiting
Heart Health and Eye Injections Study
This study looks at how repeated eye injections of a drug called bevacizumab affect chemicals in your blood that relate to heart health and inflammation. Researchers want to understand if these eye injections might impact your cardiovascular risk.
Erzurum, ErzurumAges 50–80 - NCT07549711Enrolling by invitation
Understanding Long Anterior Zonule Eye Condition and Genes
This research study examines a rare eye condition called long anterior zonule (LAZ) that affects the structures supporting the lens. Researchers will compare people with this condition to those without it, and study families where LAZ runs in the family, to understand how genes and physical eye changes relate to this condition.
Fuzhou, FujianAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.