Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT06974162Recruiting
Decoding eye inflammation with genetic sequencing
This trial uses a new genetic test to find the cause of eye inflammation when standard tests haven't. The goal is to see if this approach can identify hidden infections and help doctors choose the right treatment to protect your vision.
LondonAges Any age - NCT07693205RecruitingPhase 4
Comparing two lens types for cataract surgery with astigmatism
This study compares two types of artificial lenses placed during cataract surgery to see which one gives better vision for people with cataracts and astigmatism. You will receive the same type of lens in both eyes.
Sugar Land, TexasAges 22 years+ - NCT07713056Recruiting
Studying a glaucoma surgery for pigmentary glaucoma
This trial looks at how well a specific type of surgery (ab-interno 120° trabeculotomy) works for people with pigmentary glaucoma. It aims to understand the safety and effectiveness by tracking eye pressure and vision over time.
Wuhan, HubeiAges 16–80 - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07149142Recruiting
AI eye screening for children with type 1 diabetes
This study tests if an artificial intelligence (AI) system can effectively screen for eye problems related to diabetes (retinopathy) in children. The goal is to find a faster, easier way to protect your child's vision.
Prague, Prague 5Ages 11–19 - NCT06723106Enrolling by invitationPhase 1
Long-term safety study of RAY121 for immune conditions
This study is for people who already took RAY121 in a previous trial and did well. It tests whether continuing the treatment is safe and effective over a longer period. The goal is to manage chronic immune conditions.
Camperdown, New South WalesAges 18–85 - NCT06237127Recruiting
Goji berries vs. fiber for age-related macular degeneration
This study compares the effects of eating goji berries versus taking fiber wafers on age-related macular degeneration (AMD). It looks at whether goji berries or fiber can help slow down the eye condition, especially for people with a family history of AMD.
Sacramento, CaliforniaAges 65–95 - NCT07707817Recruiting
Expanding preventive medicine access for mobile groups
This study tests whether giving preventive medicine to people who move or migrate can help control river blindness and lymphatic filariasis. It focuses on children and household heads who have missed past treatment rounds.
Ondo, Ondo, Taraba and Akwa IbomAges 5 years+ - NCT05145491Recruiting
Immediate or delayed surgery for vision changes from ERM
This trial compares doing ERM surgery right away versus waiting at least 4 weeks to see if your vision stays stable. It may help people decide the safest timing for surgery when the membrane in the retina (ERM) is causing symptoms.
Scottsdale, ArizonaAges 50 years+ - NCT07519902RecruitingPhase 3
Cenegermin Eye Drops for Persistent Corneal Ulcers
This study tests whether cenegermin eye drops help heal stubborn corneal ulcers (open sores on the clear front of the eye) that haven't improved with standard treatments like lubricating drops or contact lenses.
Huntington Beach, CaliforniaAges 18 years+ - NCT07453888RecruitingPhase 3
Nose spray for sudden vision loss from optic nerve damage
This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.
Los Angeles, CaliforniaAges 50–80 - NCT07482176RecruitingPhase 3
Gene therapy trial for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (IXO-vec) for people with wet age-related macular degeneration (nAMD). It aims to reduce the need for frequent eye injections by helping the eye make its own medicine to block the growth of harmful blood vessels.
Mesa, ArizonaAges 50 years+ - NCT02821767Recruiting
Study of how different eye problems develop and change over time
This study follows people with eye conditions (including when the diagnosis is unclear) to learn what causes them and how they change. It may help by giving you closer eye evaluations and contributing knowledge that could improve care for future patients.
Bethesda, MarylandAges 1 month–100 years - NCT00346814RecruitingPhase 2/Phase 3
Bevacizumab injections for severe eye vessel disease in premature babies
This trial studies whether an anti–blood vessel medicine (bevacizumab, given by eye injection) can improve the structure of the retina in very premature babies with advanced retinopathy of prematurity. It may help when standard treatments like laser or freezing cannot be used.
Mexico City, Mexico DFAges 1 month–1 year - NCT02983370Recruiting
Cortical visual implant to help people with severe blindness
This trial studies a device that may help people with severe blindness by sending signals to the brain’s visual areas. You may be eligible if you’re an adult with long-term, severe vision loss and good overall health and can complete testing for several months.
Elche, AlicanteAges 18–70 - NCT03003572Recruiting
Test an immune marker in primary Sjögren’s disease activity
This study looks at an immune reaction (called anti-Ro/SSA IgE) to see how active primary Sjögren’s disease is. It may help doctors better understand what’s driving symptoms and activity levels over time.
BourgoinAges 18 years+ - NCT03030755Recruiting
Imaging test and personalized modeling for keratoconus
This trial uses special eye imaging to measure how your cornea (the eye’s clear front surface) changes, and then builds a personalized model for you. It may help doctors plan safer, more tailored treatment for keratoconus—especially if you’re considering LASIK.
Cleveland, OhioAges 16–80 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03059420Recruiting
Genetic study of strabismus and certain birth eye-movement disorders
This study looks for genetic (inherited DNA) causes of strabismus (eyes that don’t line up) and certain birth conditions that affect eye movement and brainstem/cranial nerves. Your participation may help researchers better understand these conditions and guide future testing and care.
Boston, MassachusettsAges 1 day+ - NCT03062085Recruiting
Study for people with cataracts in Shanghai
This study looks at people who have been diagnosed with cataracts. It checks whether participants can safely and reliably complete eye examinations that the study needs.
Shanghai, Shanghai MunicipalityAges 20–100 - NCT03083431RecruitingPhase 2
Oral propranolol to prevent early retinopathy in preemies
This trial tests whether giving propranolol by mouth to certain very premature babies with early eye changes can stop retinopathy of prematurity from getting worse. It may help reduce the need for eye treatments later on.
Tübingen, Baden-WurttembergAges 1 month–3 months
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.