Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT05438732Recruiting
Test of an implanted eye device plus vision training for AMD
This study tests a device that is surgically implanted in the eye of people with late-stage age-related macular degeneration (AMD). It also uses vision training with a telescope-like tool to see if the treatment can improve day-to-day vision.
Loma Linda, CaliforniaAges 65 years+ - NCT06392906RecruitingPhase 3
Radiation for Graves' Eye Disease: 1 vs 2 Weeks
This trial tests if a shorter course of radiation (1 week) works as well as a standard longer course (2 weeks) for treating active thyroid eye disease that did not improve enough with steroid medicine. It may be an option if you still have eye symptoms after steroid treatment.
Bangkok NoiAges 18–70 - NCT07597200RecruitingPhase 1
Cizutamig treatment for active thyroid eye disease
This study tests a new drug called cizutamig for thyroid eye disease (TED), a condition where the eye muscles and tissues swell due to Graves' disease. The drug is designed to reduce inflammation and may help improve symptoms like eye bulging, double vision, and discomfort.
Hefei, AnhuiAges 18–75 - NCT07595432Recruiting
Vision Technique for Cataract Lens Implant Patients
This study tests a new way to measure and optimize vision in patients who have already had cataract surgery with a lens implant. Researchers want to see if this technique helps patients see as clearly as possible.
ManilaAges 21 years+ - NCT06717048Recruiting
Finding the best red light therapy for myopia in children
This study tests whether a special red light therapy can help slow down the progression of nearsightedness in children. It compares different amounts of light and how often it is used to find the best way to keep myopia from getting worse.
Shanghai, Shanghai MunicipalityAges 8–10 - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT06714799Recruiting
Skin lesion analysis study for eye and eyelid growths
This study looks at skin growths near the eye using a special camera. It may help doctors better understand and diagnose these growths without needing a biopsy.
BolognaAges 18 years+ - NCT06718816Recruiting
Long-term follow-up of AL-001 eye injection for wet AMD
This trial is a long-term follow-up for people who already received the AL-001 eye injection for wet age-related macular degeneration (wet AMD) in an earlier study. It will check how you are doing over time.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07593885Recruiting
Comparing two eye drops for moderate to severe dry eye
This study compares two preservative-free eye drops, Artelac Complete MDO and Vismed Multi, to see how well they work and how safe they are for people with moderate to severe dry eye disease. If you have dry eye due to certain conditions (like Sjögren's syndrome) and standard eye drops haven't fully helped, this study may be an option.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT07593404Recruiting
Testing a New Eye Drop for Dry Eye Disease
This study tests a new lubricating eye drop designed to relieve dry eye symptoms. If you have dry eye disease, this trial may help determine if the new formula works better than what's currently available.
Waterloo, OntarioAges 18 years+ - NCT07594236RecruitingPhase 1
Experimental Cell Therapy for Retinal Degeneration
This early-stage study tests a new cell-based treatment (C.001) for inherited retinal diseases that affect the back of the eye. The treatment may help slow vision loss or improve sight in people with geographic atrophy or Stargardt disease.
Beverly Hills, CaliforniaAges 18 years+ - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT07587515RecruitingPhase 1/Phase 2
New Eye Drop Treatment for Wet Age-Related Macular Degeneration
This study tests a new experimental eye drop (EYC-0305) for wet AMD, a common cause of vision loss in older adults. The goal is to see if it can slow or prevent further damage to central vision.
Beverly Hills, CaliforniaAges 50 years+ - NCT07588152RecruitingPhase 4
How Netarsudil Eye Drops Affect the Eye's Drain System
This study uses special imaging to see how the eye-pressure-lowering medication netarsudil (Rhopressa) works on the part of your eye that drains fluid. Researchers want to understand whether it helps restore normal drainage in people with high eye pressure or glaucoma.
Bloomington, IndianaAges 18 years+ - NCT07589894Enrolling by invitation
Vision outcomes after cataract surgery with TruPlus lenses
This study measures how well people see after cataract removal surgery using a special TruPlus intraocular lens (an artificial lens placed in the eye). Researchers want to understand if this lens helps patients see clearly at distance with minimal side effects.
Encino, CaliforniaAges 50–80 - NCT07586787Recruiting
Early Vitrectomy vs Laser for Early Diabetic Eye Disease
This trial compares two treatments for early diabetic retinopathy—a condition where high blood sugar damages blood vessels in the eye. Researchers want to see if removing fluid from inside the eye (vitrectomy) works better than laser treatment to prevent vision loss.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07586982Recruiting
Testing New Bifocal Toric Contact Lenses for Astigmatism
This study evaluates how well new bifocal contact lenses work for people over 40 who have astigmatism (blurred vision at all distances) and need reading help. You'll wear the lenses daily for about a month and share feedback via text message to help researchers understand comfort and vision quality.
Memphis, TennesseeAges 18–40 - NCT06720376Recruiting
Uveitis and arthritis study for Turkish patients
This study follows people with uveitis (eye inflammation) to learn more about how it relates to spondyloarthritis (arthritis of the spine). You may be able to join if you have uveitis, but not if you already had spondyloarthritis before your uveitis started or if your uveitis is caused by an infection.
Istanbul, MaltepeAges 18–75 - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT07579130Recruiting
Measuring tear film thickness in dry eye disease
This study compares different ways of measuring the tear film layer (the oily coating on your eye) in people with dry eye disease. Understanding these measurements better may help doctors diagnose and treat dry eye more effectively.
Bloomington, IndianaAges 18–100 - NCT07580014Recruiting
Eye Imaging Study for Glaucoma and Narrow Angles
This study uses advanced eye imaging (OCT and OCTA) to understand how the blood vessels and tissue layers in the back of the eye differ between people with glaucoma, people at risk for angle-closure glaucoma, and people with healthy eyes. The findings may help doctors better diagnose and understand these eye conditions.
Guangzhou, GuangdongAges 18–90 - NCT07582042Recruiting
Vision testing in geographic atrophy treated with pegcetacoplan
This study tests a specialized vision-testing method in people with geographic atrophy (a type of dry age-related macular degeneration) who are already receiving pegcetacoplan injections. The goal is to better understand how this treatment affects vision in different parts of the eye.
Salt Lake City, UtahAges 65–90
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.