Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT07747662Enrolling by invitation
Eye imaging study for early geographic atrophy
This study uses special eye imaging to look closely at areas of damage in the back of the eye (geographic atrophy) caused by age-related macular degeneration. It will help doctors understand early-stage disease better and may guide future treatments.
Madison, WisconsinAges 50 years+ - NCT07630649RecruitingPhase 2
Gene therapy for wet age-related macular degeneration in second eye
This study tests a one-time gene therapy injection (ixoberogene soroparvovec) in the second eye of people with wet age-related macular degeneration who have already responded well to anti-VEGF injections. The goal is to see if this gene therapy can help preserve or improve vision in that eye.
Phoenix, ArizonaAges 50 years+ - NCT07745062RecruitingPhase 4
Comparing two eye drops for mild to moderate dry eye
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
La Jolla, CaliforniaAges 18 years+ - NCT07594236RecruitingPhase 1
Experimental Cell Therapy for Retinal Degeneration
This early-stage study tests a new cell-based treatment (C.001) for inherited retinal diseases that affect the back of the eye. The treatment may help slow vision loss or improve sight in people with geographic atrophy or Stargardt disease.
Beverly Hills, CaliforniaAges 18 years+ - NCT07269665RecruitingEarly Phase 1
Gene therapy trial for children with BBS1 retinal degeneration
This early-phase trial tests a gene therapy called AXV-101 for children with vision loss caused by BBS1 genetic mutations. The goal is to see if it can help slow or stop retinal damage.
LondonAges 4–17 - NCT05878860RecruitingPhase 3
RS1-related retinoschisis gene therapy for vision improvement
This Phase 3 trial tests a gene therapy (ATSN-201) to improve or preserve vision in people with RS1-associated X-linked retinoschisis (XLRS), a genetic eye condition. You may qualify if you have a certain level of vision and specific eye “schisis” changes seen on a scan.
Phoenix, ArizonaAges 6 years+ - NCT07144137Recruiting
Observation study for geographic atrophy progression
This study observes how geographic atrophy (an advanced form of dry age-related macular degeneration) changes over a short period. If you have this condition in both eyes and meet certain vision and eye health criteria, you may be able to join this non-treatment study to help researchers learn more about the disease.
Mountain View, CaliforniaAges 55 years+ - NCT07740590Recruiting
Comparing artificial lenses for cataract surgery and quality of life
This study compares different types of artificial lenses (IOLs) placed during cataract surgery to see which helps your eyes adapt and improves your quality of life best. It is for people having cataract surgery on both eyes who have very little natural corneal curve (astigmatism).
ChengduAges 18–100 - NCT07739784Recruiting
Personality and side effects of glaucoma eye drops
This study looks at whether your personality affects how you experience side effects from glaucoma eye drops. The results may help doctors choose the best treatment for you and provide more personalized care.
Montreal, QuebecAges 18 years+ - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT06980649RecruitingPhase 1
Study of BHV-1300 in Graves' Disease
This trial tests a new treatment called BHV-1300 for people with Graves' disease. It aims to see if the drug is safe and works well. If you have Graves' disease confirmed by blood tests, you may be able to join.
South Gate, CaliforniaAges 18–65 - NCT07434635RecruitingPhase 4
Atropine for pain after vitrectomy surgery
This study tests whether atropine eye drops can reduce pain and prevent scar tissue (called posterior synechiae) after vitrectomy surgery. The goal is to see if this treatment helps you recover more comfortably.
San Francisco, CaliforniaAges 18 years+ - NCT07036510RecruitingPhase 1/Phase 2
Safety and effectiveness of a timolol eye implant for glaucoma patients having cataract surgery
This trial tests a sustained-release implant that delivers timolol, a medicine to lower eye pressure, for people with glaucoma or high eye pressure who are also having cataract surgery. The implant is placed during surgery and may provide long-term pressure control without daily eye drops.
Panama CityAges 40 years+ - NCT04743141RecruitingPhase 3
Long-term migraine medicine study for kids with migraine attacks
This Phase 3 study checks the long-term safety of rimegepant, a migraine treatment, in children and teens. You might join if your child has had migraine for at least 6 months and still gets a certain number of moderate-to-severe migraine attacks.
Scottsdale, ArizonaAges 6–17 - NCT07705893Recruiting
Treating contact lens discomfort with a nasal spray
This trial tests a nasal spray (varenicline) to see if it can relieve discomfort and dryness from contact lens wear. If you wear daily disposable soft contacts and experience end-of-day eye dryness, you may be eligible.
Houston, TexasAges 18–99 - NCT07226141RecruitingPhase 1/Phase 2
Valproate for persistent lazy eye in children and teens
This trial tests if the medication valproate (a seizure drug) can improve vision in children and teens aged 8-17 who still have a lazy eye (amblyopia) even after wearing glasses or patching. It may help if your child's vision has stopped getting better with standard treatments.
Boston, MassachusettsAges 8–17 - NCT07161544RecruitingPhase 1/Phase 2
Gene therapy for Stargardt disease
This trial tests a new gene therapy, AAVB-039, for people with Stargardt disease caused by a specific gene mutation. The treatment is given during eye surgery and aims to slow or stop vision loss.
Phoenix, ArizonaAges 8–55 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT07472231Recruiting
Game-based therapy for children with lazy eye
This trial tests if a fun, game-based training program can improve vision in children with lazy eye caused by a difference in glasses prescription between the two eyes. It is designed for children ages 4 to 7 who can participate in vision exercises.
Shanghai, Shanghai MunicipalityAges 4–7 - NCT07732855Recruiting
Treating eye surface inflammation
This study tests a treatment for inflammation on the eye's surface, specifically keratitis (cornea inflammation), to see if it can help calm the redness, pain, or irritation.
Budapest, Pest CountyAges 4–60 - NCT05115058Enrolling by invitation
A new laser treatment for better near vision without glasses
This study tests a new laser procedure that creates a tiny pocket inside your cornea (the clear front part of your eye) to help you see up close without glasses. It's for people who have presbyopia (age-related trouble focusing on nearby objects) and are tired of needing reading glasses.
PristinaAges 40–50 - NCT04642729Enrolling by invitation
Fresh cornea lenticule implant for macular corneal dystrophy
This trial tests a new way to treat macular corneal dystrophy using a thin piece of clear cornea (a lenticule) from a donor. Instead of a full transplant, the surgeon uses a laser (RELEX SMILE) to insert this lenticule to improve vision.
PristinaAges 20–55 - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.