Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3132
- Phase 2121
- Phase 1121
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California142
- Arizona65
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT05650749Enrolling by invitationPhase 1
GPC2 car T cells for neuroblastoma and retinoblastoma
This trial tests a new treatment using engineered immune cells (CAR T cells) that target a protein called GPC2 found on some cancer cells. It is for patients with high-risk neuroblastoma or metastatic retinoblastoma that has returned or not responded to other treatments.
Philadelphia, PennsylvaniaAges 1 year+ - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT07761949Recruiting
How streetscape views affect children's perception
This study uses eye-tracking glasses to see how children with and without myopia (nearsightedness) look at outdoor scenes from streets and neighborhoods. The results may help design environments that support healthy vision in children.
Guangzhou, GuangdongAges 6–18 - NCT07764198Recruiting
Gabor visual training for adult lazy eye
This study tests a home-based visual training program that uses special patterns to help improve vision in adults with amblyopia, often called lazy eye. It may offer a new way to gain visual improvement.
ShanghaiAges 18–39 - NCT07762872Recruiting
Satralizumab during early NMOSD attacks
This study looks at how well the medication satralizumab works when started early during an NMOSD attack, along with standard treatments. The aim is to see if adding this drug can help reduce the impact of the attack and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07228091Recruiting
Surgery efficiency study for combined eye procedures
This study looks at how efficiently surgeons perform a combined cataract and vitrectomy surgery. It may help improve future surgical techniques. You may qualify if you are already scheduled for this specific type of eye surgery.
ManchesterAges 18 years+ - NCT07265258RecruitingPhase 4
Teprotumumab for active thyroid eye disease
This study tests a drug called teprotumumab for people with active thyroid eye disease. It is designed to help reduce eye bulging and other symptoms, and may be an option if you have not had strong treatments before.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07675811RecruitingPhase 3
Study of a new treatment for cat allergy related eye symptoms
This trial tests an injectable treatment that may help manage eye allergy symptoms caused by cat allergies. It aims to see if the treatment is safe and effective for adults and children, and includes a controlled cat exposure challenge.
Andover, MassachusettsAges 8 years+ - NCT07502378RecruitingPhase 4
Eye drops for dry eye in early neurotrophic keratopathy
This trial tests a new eye drop (acoltrepon) to see if it helps people with stage 1 neurotrophic keratopathy (a condition where the cornea's nerves are damaged, causing dry eyes and vision problems) and low tear production. It aims to improve signs like corneal staining and symptoms of discomfort.
Tampa, FloridaAges 18 years+ - NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
ParisAges 18 years+ - NCT07570316RecruitingPhase 3
Testing efgartigimod for Graves' disease hyperthyroidism
This study tests whether efgartigimod, an injectable medication given under the skin, can help control overactive thyroid (Graves' disease) in adults already taking methimazole or carbimazole. The goal is to see if it reduces thyroid antibodies and improves thyroid hormone levels.
Orange, CaliforniaAges 18 years+ - NCT04700657Recruiting
Study dryness patterns in eye graft-vs-host disease
This study looks at how common and how severe corneal nerve-related dryness is in people with chronic graft-vs-host disease (GVHD) after a stem cell transplant. It may help doctors understand which eye problems are most typical and how best to recognize them early.
Indianapolis, IndianaAges 18 years+ - NCT07264283Enrolling by invitationPhase 2
Testing LM11A-31 for progressive supranuclear palsy
This trial tests a drug called LM11A-31 to see if it can help people with progressive supranuclear palsy (PSP), a rare brain condition. You may join if you have had symptoms for 5 years or less, can walk with minimal help, and have good thinking abilities.
San Francisco, CaliforniaAges 41–86 - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT07347379Enrolling by invitation
Long-term follow-up for people with the light adjustable lens
This study checks how well the light adjustable lens (a special artificial lens used in cataract surgery that can be adjusted after it's placed in the eye) holds up over time in people who already have it.
San Antonio, TexasAges Any age - NCT07758569Recruiting
AI tool for detecting glaucoma in eye photos
This study is testing an artificial intelligence tool that can automatically detect signs of glaucoma in photos of the retina. It may help confirm that the AI can accurately identify glaucoma, which could lead to faster diagnosis and monitoring for patients.
AlexandroupoliAges 18 years+ - NCT07758582Recruiting
Artificial intelligence for detecting diabetic retinopathy from eye photos
This study tests an AI system that automatically detects signs of diabetic retinopathy from eye photos. It aims to see if the AI can accurately identify these signs to help with early detection.
AlexandroupoliAges 18 years+ - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT07041099RecruitingPhase 1
Study of CLN-978 for Sjögren's disease
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
Orlando, FloridaAges 18 years+ - NCT06541704RecruitingPhase 3
Study of pozelimab with cemdisiran for geographic atrophy
This trial tests a combination of two study drugs (pozelimab and cemdisiran) given as a shot under the skin to slow the progression of geographic atrophy, a type of advanced dry age-related macular degeneration that causes blind spots in central vision.
Chandler, ArizonaAges 50–85 - NCT07607496Recruiting
MacuTherm laser treatment study for intermediate age-related macular degeneration
This study tests a new laser treatment (MacuTherm) for intermediate age-related macular degeneration (iAMD), an eye condition that affects central vision. The study aims to see if this treatment can slow or prevent progression to more advanced stages of the disease.
DetmoldAges 60–90 - NCT07755761Recruiting
Tube surgery for hard-to-treat glaucoma
This study tests a new tube-based surgery to lower eye pressure in people with advanced or difficult-to-treat open-angle glaucoma. The goal is to see if this surgery works better than standard care for controlling pressure and preserving vision.
BanhāAges 18 years+ - NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT06619405Recruiting
Eye Function Test for Age-Related Macular Degeneration
This study tests a quick, noninvasive eye test that measures how well you see in the dark, which can be an early sign of dry AMD. Researchers want to see if the test relates to everyday tasks like reading or driving at night.
Durham, North CarolinaAges 50–89
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,904 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.