Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3132
- Phase 2121
- Phase 1121
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California142
- Arizona65
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT07629232Recruiting
Study of corneal thickness and shape measurements
This study measures how light passes through the clear front part of your eye (cornea) using a specialized camera. These measurements help doctors better understand eye health and may improve future eye care.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT05844982RecruitingPhase 3
Eye injections or steroid implant to prevent vision loss
This trial studies ways to prevent worsening vision caused by radiation damage to the retina after plaque brachytherapy for uveal melanoma. You may be randomly assigned to a medication injection, a steroid implant, or observation to see which approach best protects vision.
Palo Alto, CaliforniaAges 18 years+ - NCT03675412Recruiting
Testing how caffeine affects eyes in glaucoma
This study compares how caffeine changes eye measurements in people with primary open-angle glaucoma versus people without eye disease. It may help researchers understand whether caffeine intake could affect vision-related eye signals.
Philadelphia, PennsylvaniaAges 18–90 - NCT07774637Recruiting
Surgery outcomes for myopic foveoschisis
This study is looking at how well people do after eye surgery for a condition called myopic foveoschisis, which causes a part of the retina to swell. The study will check if your vision improves after surgery and look for signs of complications.
Singapore, SingaporeAges 40–90 - NCT03299530Recruiting
Testing how corneal astigmatism measures on different settings
This study checks how accurately eye measurements describe astigmatism (a focus-bending problem) using different exam modes. It may help improve how doctors assess astigmatism after cataract surgery so treatment planning is more precise.
Wenzhou, ZhejiangAges 18 years+ - NCT07636785RecruitingPhase 1/Phase 2
VMD-102 Drug Study for Advanced Cancers
This study tests a new drug called VMD-102 in patients with advanced liver cancer, melanoma, kidney cancer, lung cancer, or colon cancer that hasn't responded to standard treatments. The trial will help determine if VMD-102 is safe and effective at slowing or stopping cancer growth.
Scottsdale, ArizonaAges 18–75 - NCT07338968Enrolling by invitation
Long-term follow-up for early choroidal melanoma study
This study follows people who finished a previous trial for a type of eye cancer called early choroidal melanoma. It checks how patients are doing over time after receiving either the study treatment (bel-sar) or a placebo (sham).
Sacramento, CaliforniaAges 18 years+ - NCT07771699Recruiting
Brain stimulation for balance and thinking in older adults with glaucoma
This study tests a non-invasive brain stimulation technique to see if it can improve balance and thinking in older adults with glaucoma. It involves a series of sessions where a mild electrical current is applied to the brain.
Kowloon, Hong KongAges 55 years+ - NCT06258707Recruiting
Testing a new artificial lens for cataract surgery
This study tests a new artificial lens (LuxBoost IOL) designed to safely improve vision after cataract surgery in both eyes. It may be a good option if you have cataracts in both eyes, have healthy eyes with no prior surgery, and need a standard lens power.
MontaubanAges 50 years+ - NCT03059043Recruiting
ICL lens surgery using a low-contact method in near-sighted eyes
This trial studies whether a specific, “viscoelastic-free” technique for implantable collamer lens (ICL) surgery is safe and works well for people with stable near-sightedness. It may help by improving the way the lens is inserted while closely monitoring eye safety and vision results.
Guangzhou, GuangdongAges 18–45 - NCT07621809RecruitingPhase 3
Ianalumab versus placebo for Sjögren's disease with high symptom burden
This study tests whether a new drug called ianalumab can reduce dry mouth and other symptoms in people with Sjögren's disease—a condition where the immune system attacks moisture-producing glands. Participants will receive either ianalumab or a placebo (inactive injection) over 52 weeks to see if the drug helps.
Peoria, ArizonaAges 18 years+ - NCT07722247Recruiting
Eye stiffness and healing in cataract surgery with PEX
This study looks at how your eye's outer layer (cornea) heals and changes shape after cataract surgery, specifically comparing people who have pseudoexfoliation syndrome (PEX) with those who do not. The goal is to see if PEX affects the final vision result after cataract removal.
Split, Splitsko-dalmatinska CountyAges 50–85 - NCT00305305Recruiting
Brain development study for rare brain conditions
This study looks at how the brain develops in people with certain rare conditions that affect brain structure. It may help researchers understand these conditions better and could lead to improved care.
San Francisco, CaliforniaAges Any age - NCT07266584Recruiting
Retinal implant for central vision loss in inherited eye disease
This trial tests a new implant (PRIMA) placed under the retina to help restore central vision in people with inherited retinal degeneration. If you have very poor central vision and a large enough area of retinal damage, this device may help you see better.
Sydney, New South WalesAges 18 years+ - NCT05275972RecruitingPhase 3
Compare cornea surgery thickness results for FECD
This Phase 3 trial compares outcomes from two cornea transplant procedures in people with FECD, a disease that makes the cornea swell and affect vision. It may help you and others by identifying which approach best supports clear vision and stable corneal thickness after surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT07430735Recruiting
Moisture chamber glasses for dry eye relief
This trial tests a special pair of glasses that create a moisture chamber to relieve dry eye symptoms. It is for adults with mild to moderate dry eye who already wear glasses.
Rochester, New YorkAges 18 years+ - NCT06894017Recruiting
Same-Day Eye Injections: Patient Preferences Study
This study asks patients who have had a dexamethasone implant in their eye about their preferences for having injections in both eyes on the same day versus separate days. The goal is to understand what patients prefer, which could help make treatment more convenient in the future.
Glostrup MunicipalityAges 18 years+ - NCT06701617Recruiting
Vision training for children with low vision
This study tests two types of vision training for children with low vision, either in person or through telehealth. It aims to help improve how children use their remaining vision.
TaipeiAges 1 month–18 years - NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Glendale, ArizonaAges 45 years+ - NCT07007065RecruitingPhase 3
Study of a gene therapy for wet age-related macular degeneration
This trial tests a one-time gene therapy injection for wet AMD that may reduce the need for regular eye injections. It is for people who have already responded to anti-VEGF injections but want a longer-lasting treatment.
Mesa, ArizonaAges 50 years+ - NCT07623668RecruitingPhase 3
Testing a new drug for sudden vision loss from nerve inflammation
This study tests whether a new medication called privosegtor can help restore vision in people who recently experienced sudden vision loss in one eye due to optic nerve inflammation. You would receive the study drug early after your symptoms start, when treatment may be most effective.
Livonia, MichiganAges 18–50 - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Peoria, ArizonaAges 18 years+ - NCT06659549RecruitingPhase 2
Eye drop treatment for advanced dry AMD with geographic atrophy
This trial tests a daily eye drop (GAL-101) to see if it can slow the growth of geographic atrophy lesions in people with dry age-related macular degeneration (AMD) when the center of the macula is not yet involved.
Beverly Hills, CaliforniaAges 55 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,904 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.