Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06906003Recruiting
Vision rehab and depression in age-related macular degeneration
This trial tests whether visual rehabilitation can help improve both vision and mood in people with advanced dry age-related macular degeneration. It aims to understand the link between vision loss and depression.
Rome, ItalyAges 55 years+ - NCT06908824Recruiting
No gas bubble for macular hole repair trial
This trial tests if macular hole surgery can be done without a gas bubble in the eye, which might make recovery easier. It is for people who have a macular hole and can lie face-down after surgery.
Hong KongAges 18 years+ - NCT06911424RecruitingPhase 3
Fusidic acid eye drops for bacterial pink eye
This trial tests an antibiotic eye drop called fusidic acid for bacterial conjunctivitis (pink eye). It may help clear the infection if you have had symptoms for less than 48 hours and have not used other eye treatments recently.
Little Rock, ArkansasAges Any age - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT06915922Recruiting
Laser treatment for bothersome eye floaters
This trial tests a special laser (YAG laser) to break up annoying eye floaters. It's for people whose floaters have been bothering them for at least 3 months and come from being nearsighted or from a normal aging change in the eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT06919081RecruitingPhase 2
Stem cell eye drops for chronic cornea problems
This study tests whether a special substance from stem cells (called secretome) can help heal chronic surface problems on the eye that haven't gotten better with standard treatments. It's for people with a stubborn scratch or defect on the cornea that has lasted more than 14 days.
Chicago, IllinoisAges 18 years+ - NCT06921317RecruitingPhase 1/Phase 2
Gene therapy for advanced glaucoma
This trial tests a gene therapy treatment called GVB-2001 for people with primary open angle glaucoma. It involves a one-time injection into the eye to help lower eye pressure, and could be an option if you have tried other treatments that haven't worked well enough.
Suzhou, JiangsuAges 18–75 - NCT06921967Recruiting
Rigid contact lenses for keratoconus
This study tests how well rigid gas permeable (RGP) contact lenses work for people with keratoconus, a condition where the cornea becomes cone-shaped. It looks at eye health and vision quality.
AarhusAges 18–40 - NCT06922084RecruitingPhase 4
Comparing three types of artificial lens implants for cataract surgery
This study tests different artificial lens implants (called intraocular lenses or IOLs) to see which gives the best vision after cataract surgery. If you have cataracts in both eyes and need surgery, you may be able to join.
Plymouth Meeting, PennsylvaniaAges 40 years+ - NCT06924021Recruiting
AMD Eye Image Library (ABID) Study
This study is creating a library of eye images to help doctors better diagnose age-related macular degeneration (AMD). You can join if you have healthy eyes or any stage of AMD that has never been treated.
Fargo, North DakotaAges 50 years+ - NCT06927375RecruitingPhase 4
Combination drug therapy for thyroid eye disease
This study tests a combination of two drugs, tocilizumab and flupentixol-melitracen, in people with active, moderate-to-severe thyroid-associated eye disease (TED). It aims to see if this combination can reduce eye bulging, double vision, and anxiety symptoms.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06928727Recruiting
Eye health in craniosynostosis study
This study looks at eye features in people with craniosynostosis (a condition where skull bones fuse too early). It may help doctors better understand eye problems that can occur with this condition.
AmiensAges Any age - NCT06932757RecruitingPhase 2
Quisinostat after treatment for high-risk uveal melanoma
This trial tests whether taking quisinostat pills after standard treatment can lower the chance of uveal melanoma coming back in people whose original tumor had high-risk features. It is for patients who have finished their eye treatment (surgery or radiation) within the past 6 months and have no signs that the cancer has spread.
Miami, FloridaAges 19 years+ - NCT06932809RecruitingEarly Phase 1
Brain Uptake Study of a New Imaging Tracer
This study uses a special PET scan to see how a new tracer (18F-JSS20-183A) moves through the body and brain. It may help researchers learn more about brain diseases like Parkinson's and Alzheimer's.
San Francisco, CaliforniaAges 40–85 - NCT06933836Recruiting
DSLT laser for newly diagnosed open-angle glaucoma
This trial tests a laser treatment called DSLT in people recently diagnosed with open-angle glaucoma who have never had any other glaucoma treatment. It aims to see how well the laser lowers eye pressure.
Mesa, ArizonaAges 30 years+ - NCT06934577Recruiting
Glaucoma screening and eye health study via telemedicine
This study tests if telemedicine can help find glaucoma and other eye problems early. It may help people who speak one of several languages and want to check their eye health from home.
Flint, MichiganAges 18 years+ - NCT06935227Recruiting
Steri-Strip tape for ectropion surgery on one eye
This study tests whether using Steri-Strip tape (a special medical tape) during surgery for a drooping lower eyelid (ectropion) on one eye gives better results. It is for adults who need this specific surgery and do not have certain skin conditions or take a strong acne medicine.
BogotáAges 18 years+ - NCT06936787RecruitingPhase 1
Study of IGT001 for retinitis pigmentosa
This trial tests an experimental drug called IGT001 for people with retinitis pigmentosa, a genetic eye disease that causes vision loss. The goal is to see if it is safe and can help slow or improve vision.
ShanghaiAges 18 years+ - NCT06939166RecruitingEarly Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases
This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06940739RecruitingPhase 1/Phase 2
IOV-3001 and lifileucel for advanced melanoma
This trial tests a new combination treatment, IOV-3001 and lifileucel, for people with advanced melanoma that has not responded to standard immunotherapy and cannot be surgically removed. It aims to see if this cellular therapy is safe and effective.
Denver, ColoradoAges 18–70 - NCT06941584Recruiting
AIRE gene's role in autoimmune nerve diseases
This study looks at how the AIRE gene affects people with autoimmune nerve diseases like NMOSD, myasthenia gravis, and autoimmune encephalitis when they also have other autoimmune conditions. It may help researchers understand why some people get multiple autoimmune problems.
RomaAges 18 years+ - NCT06942572RecruitingPhase 1/Phase 2
Gene therapy trial for Stargardt disease
This trial tests a new gene therapy called SB-007 for people with Stargardt disease (STGD1). It is given as an injection under the retina to see if it is safe and can help slow vision loss.
Aurora, ColoradoAges 12–65 - NCT06943599Recruiting
Improving Eye Care After Screening
This study looks at better ways to help people get follow-up eye care after a screening. If you were in the VIEW II study and were referred to an eye hospital, this trial may offer strategies to support you in getting that care.
San Francisco, CaliforniaAges 60 years+ - NCT06944171Recruiting
How brain-related challenges affect daily life in children with cerebral palsy
This study looks at how impairments like muscle stiffness or weakness affect daily activities and participation in children (ages 6–12) with cerebral palsy. It could help families better understand their child's needs.
AnkaraAges 6–12
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.