Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06921317RecruitingPhase 1/Phase 2
Gene therapy for advanced glaucoma
This trial tests a gene therapy treatment called GVB-2001 for people with primary open angle glaucoma. It involves a one-time injection into the eye to help lower eye pressure, and could be an option if you have tried other treatments that haven't worked well enough.
Suzhou, JiangsuAges 18–75 - NCT06921967Recruiting
Rigid contact lenses for keratoconus
This study tests how well rigid gas permeable (RGP) contact lenses work for people with keratoconus, a condition where the cornea becomes cone-shaped. It looks at eye health and vision quality.
AarhusAges 18–40 - NCT06922084RecruitingPhase 4
Comparing three types of artificial lens implants for cataract surgery
This study tests different artificial lens implants (called intraocular lenses or IOLs) to see which gives the best vision after cataract surgery. If you have cataracts in both eyes and need surgery, you may be able to join.
Plymouth Meeting, PennsylvaniaAges 40 years+ - NCT06919081RecruitingPhase 2
Stem cell eye drops for chronic cornea problems
This study tests whether a special substance from stem cells (called secretome) can help heal chronic surface problems on the eye that haven't gotten better with standard treatments. It's for people with a stubborn scratch or defect on the cornea that has lasted more than 14 days.
Chicago, IllinoisAges 18 years+ - NCT06590220Recruiting
Predicting treatment needs for moderate to severe thyroid eye disease
This study aims to build a model that helps doctors predict how thyroid eye disease (TAO) will progress, specifically for patients with moderate to severe symptoms. If you have had TAO and meet the activity criteria, your participation could lead to better personalized care.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06902584Recruiting
Comfilcon A contact lens study for current wearers
This study is for people who currently wear Comfilcon A contact lenses (including sphere, toric, multifocal, toric multifocal, or Energys) and have used them for at least a year. It also requires that you sometimes sleep in your lenses. The purpose is to gather ongoing information about these lenses.
Berkeley, CaliforniaAges 8–75 - NCT06911424RecruitingPhase 3
Fusidic acid eye drops for bacterial pink eye
This trial tests an antibiotic eye drop called fusidic acid for bacterial conjunctivitis (pink eye). It may help clear the infection if you have had symptoms for less than 48 hours and have not used other eye treatments recently.
Little Rock, ArkansasAges Any age - NCT05561127RecruitingPhase 3
Paclitaxel balloon to treat stubborn non-cancer bowel narrowing
This trial studies a medicine-coated balloon (paclitaxel) placed during endoscopy to keep a non-cancer bowel narrowing (stricture) open longer. It may help reduce repeat procedures if standard balloon dilation hasn’t worked well enough.
Scottsdale, ArizonaAges 22 years+ - NCT06906003Recruiting
Vision rehab and depression in age-related macular degeneration
This trial tests whether visual rehabilitation can help improve both vision and mood in people with advanced dry age-related macular degeneration. It aims to understand the link between vision loss and depression.
Rome, ItalyAges 55 years+ - NCT06903884RecruitingPhase 3
Diquafosol eye drops for moderate-to-severe eye allergy
This trial tests a new eye drop called diquafosol for people with a severe, active eye allergy called vernal keratoconjunctivitis. It aims to see if the drops can calm the allergy and help heal the surface of the eye.
Hong KongAges 6 years+ - NCT06908824Recruiting
No gas bubble for macular hole repair trial
This trial tests if macular hole surgery can be done without a gas bubble in the eye, which might make recovery easier. It is for people who have a macular hole and can lie face-down after surgery.
Hong KongAges 18 years+ - NCT06424301RecruitingEarly Phase 1
Targeted gene therapy for hard-to-treat retinoblastoma
This trial tests an experimental drug that targets a specific gene (NUDT21) to treat retinoblastoma that has not responded to standard treatments. It is for children who have active tumor in only one eye and whose only other option is to remove the eye, but who want to try to save the eye instead.
ShanghaiAges 6 months+ - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06844123Recruiting
Robot-assisted corneal transplant surgery study
This study tests a new robot-assisted surgical technique for doing a full-thickness corneal transplant. The goal is to see if the robot can help make the surgery more precise and safer.
ReimsAges 18–60 - NCT06895044Recruiting
How myopic children's eyes grow over time
This study follows how the eyes of children with nearsightedness (myopia) grow over time. It aims to learn more about how myopia changes as children get older.
ParisAges 6–17 - NCT06891443RecruitingPhase 3
Study of Sepofarsen for LCA type 10
This study tests an investigational RNA therapy called sepofarsen for people with Leber Congenital Amaurosis (LCA) type 10, a rare inherited eye disease that causes severe vision loss from birth. The goal is to see if it can slow or improve vision loss.
San Francisco, CaliforniaAges 6 years+ - NCT06891885RecruitingPhase 1/Phase 2
Safety study of DSP-3077 for retinitis pigmentosa
This trial tests a new medicine, DSP-3077, given as a single injection into one eye to see if it is safe for people with retinitis pigmentosa. It is for adults with advanced vision loss who have no other major eye diseases.
Boston, MassachusettsAges 18 years+ - NCT06748703Recruiting
Optic nerve injury in obstructive sleep apnea patients
This study looks at whether sleep apnea affects the optic nerve, which connects your eye to your brain. It is for people newly diagnosed with sleep apnea who have not yet received treatment.
Nanjing, JiangsuAges 18–80 - NCT06893965Recruiting
Eye pressure check after Eylea 8mg injection
This trial measures eye pressure right after an injection of a higher-dose Eylea (aflibercept 8mg) to see how it affects the eye. It may help people who need frequent anti-VEGF shots for conditions like wet AMD or diabetic eye disease.
Toulon, VarAges 18 years+ - NCT06895902RecruitingEarly Phase 1
Eyelid spring for closing the eye in facial paralysis
This trial tests a tiny spring placed in the eyelid to help you close your eye if it stays open due to facial nerve paralysis. It may be an option if your eye has not improved after 6 weeks.
Edmonton, AlbertaAges 18 years+ - NCT06891092Recruiting
Comparing two types of artificial lens implants for cataract surgery
This study is comparing two different artificial lens implants used during cataract surgery to see which one works better. You may be a candidate if you have cataracts in both eyes and are generally healthy.
Bialystok, PolskaAges 21–80 - NCT06898853Recruiting
Eye drops for dry eye: A 12-week study
This trial tests whether an anti-inflammatory eye drop (ciclosporin A) can help dry eyes by changing immune cells on the eye's surface. It lasts 12 weeks and may be an option for people with moderate to severe dry eye.
Sydney, New South WalesAges 18 years+ - NCT06886737RecruitingPhase 1
Home vision therapy for veterans with double vision
This trial tests if a 12-week home-based vision therapy program can improve double vision and reading issues in veterans with traumatic brain injury. It targets a specific problem called convergence insufficiency, where the eyes don't work together when looking at close objects.
Cleveland, OhioAges 18–80 - NCT06882356Recruiting
AI eye screening for diabetic retinopathy
This study uses an AI-based system to check for diabetic retinopathy during regular eye exams at primary care clinics. It may help catch vision problems early if you have diabetes.
Boston, MassachusettsAges 40 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.