Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06963203Recruiting
Surgery for hyperthyroidism from Graves' or amiodarone use
This study looks at thyroid removal surgery for hyperthyroidism caused by Graves' disease or the heart medication amiodarone. It aims to see how well the surgery works for these patients.
AalstAges 18 years+ - NCT06952842RecruitingPhase 1/Phase 2
Gene therapy trial for retinitis pigmentosa with RHO mutation
This trial tests a new gene therapy called ZVS203e for people with retinitis pigmentosa caused by a specific RHO gene mutation. It aims to see if the treatment is safe and can help improve vision.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06935227Recruiting
Steri-Strip tape for ectropion surgery on one eye
This study tests whether using Steri-Strip tape (a special medical tape) during surgery for a drooping lower eyelid (ectropion) on one eye gives better results. It is for adults who need this specific surgery and do not have certain skin conditions or take a strong acne medicine.
BogotáAges 18 years+ - NCT06961357RecruitingPhase 1/Phase 2
CD40L-Enhanced TIL therapy for advanced melanoma
This trial tests a new way to treat advanced melanoma by taking immune cells from your tumor, enhancing them in the lab to fight better, and giving them back to you. It is for people whose melanoma has spread or cannot be removed, and who have already tried standard treatments.
Tampa, FloridaAges 18 years+ - NCT06961864Recruiting
Brain function in visual snow syndrome
This study uses visual tests and brain scans to understand how the brain processes vision in people with visual snow syndrome compared to those without. It may help researchers learn more about what causes this condition.
Minneapolis, MinnesotaAges 18–60 - NCT06952153Recruiting
Comparing two surgeries for glaucoma with cataract
This trial compares two types of eye surgery—one that removes the cataract and opens blocked drainage channels, and another that creates a new drainage pathway. It aims to find which works better for people with both glaucoma and cataracts.
Ho Chi Minh CityAges 40 years+ - NCT06952452RecruitingPhase 3
Testing genes to improve AMD treatment
This trial studies how genes affect response to anti-VEGF injections for a common form of age-related vision loss (wet AMD). It aims to tailor treatment to each patient.
San Cristóbal de La Laguna, Santa Cruz De TenerifeAges 50 years+ - NCT06943599Recruiting
Improving Eye Care After Screening
This study looks at better ways to help people get follow-up eye care after a screening. If you were in the VIEW II study and were referred to an eye hospital, this trial may offer strategies to support you in getting that care.
San Francisco, CaliforniaAges 60 years+ - NCT06951087Enrolling by invitationPhase 3
Steroid injection for diabetic retinopathy with cataract surgery
This trial tests if an injection of dexamethasone (a steroid) into the eye, before or during cataract surgery, can help treat mild to moderate diabetic retinopathy in people with type 2 diabetes.
Nantong, JiangsuAges Any age - NCT06949579Recruiting
Risk of Eye Bulge in Highly Myopic Europeans
This study looks at the risk of a back-of-the-eye bulge (posterior staphyloma) in people with high myopia. It uses existing eye images to understand the anatomy of highly myopic eyes.
ParisAges 18 years+ - NCT06305663Recruiting
Contact lens to slow myopia in children
This study tests a special contact lens designed to slow the progression of nearsightedness (myopia) in children ages 8 to 12. If your child is nearsighted and needs glasses, this lens might help reduce the need for stronger prescriptions over time.
Beijing, Beijing MunicipalityAges 8–12 - NCT06940739RecruitingPhase 1/Phase 2
IOV-3001 and lifileucel for advanced melanoma
This trial tests a new combination treatment, IOV-3001 and lifileucel, for people with advanced melanoma that has not responded to standard immunotherapy and cannot be surgically removed. It aims to see if this cellular therapy is safe and effective.
Denver, ColoradoAges 18–70 - NCT06934577Recruiting
Glaucoma screening and eye health study via telemedicine
This study tests if telemedicine can help find glaucoma and other eye problems early. It may help people who speak one of several languages and want to check their eye health from home.
Flint, MichiganAges 18 years+ - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT06932809RecruitingEarly Phase 1
Brain Uptake Study of a New Imaging Tracer
This study uses a special PET scan to see how a new tracer (18F-JSS20-183A) moves through the body and brain. It may help researchers learn more about brain diseases like Parkinson's and Alzheimer's.
San Francisco, CaliforniaAges 40–85 - NCT06932757RecruitingPhase 2
Quisinostat after treatment for high-risk uveal melanoma
This trial tests whether taking quisinostat pills after standard treatment can lower the chance of uveal melanoma coming back in people whose original tumor had high-risk features. It is for patients who have finished their eye treatment (surgery or radiation) within the past 6 months and have no signs that the cancer has spread.
Miami, FloridaAges 19 years+ - NCT06939166RecruitingEarly Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases
This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06925477Enrolling by invitation
New vs. standard laser for open-angle glaucoma
This study compares a new way of doing laser treatment for open-angle glaucoma versus the standard method. The goal is to see which approach works better at lowering eye pressure and protecting vision.
Charleston, South CarolinaAges 18 years+ - NCT06927544Enrolling by invitation
Gas bubble treatment for large macular holes
This trial tests a gas bubble procedure to repair large macular holes in people aged 50 and older. It aims to improve vision by closing the hole without traditional surgery.
OdesaAges 50–90 - NCT06931444Enrolling by invitation
Children's eye study in Beijing
This study will follow healthy primary school students for several years to understand how children's eyes develop and how to prevent vision problems. It involves a simple eye exam with drops to check for any issues.
Beijing, Beijing MunicipalityAges 6–12 - NCT06928727Recruiting
Eye health in craniosynostosis study
This study looks at eye features in people with craniosynostosis (a condition where skull bones fuse too early). It may help doctors better understand eye problems that can occur with this condition.
AmiensAges Any age - NCT06924021Recruiting
AMD Eye Image Library (ABID) Study
This study is creating a library of eye images to help doctors better diagnose age-related macular degeneration (AMD). You can join if you have healthy eyes or any stage of AMD that has never been treated.
Fargo, North DakotaAges 50 years+ - NCT05797298Recruiting
Toric lens implant surgery for cataracts
This trial studies implanting a special “toric” lens to improve vision for people with cataracts. It may help reduce the need for glasses for some people, depending on their eye measurements.
Shanghai, ChinaAges Any age - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.