Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06881368Recruiting
Understanding Susac syndrome in adults
This study looks at Susac syndrome, a rare condition that affects the brain, ears, and eyes. If you have hearing loss, vision problems, or confusion, researchers want to understand what causes it and how it affects people like you.
ParisAges 18 years+ - NCT06885957Recruiting
Monoclonal antibodies for AQP4-positive NMOSD
This trial is testing monoclonal antibody treatments for people with a specific type of neuromyelitis optica spectrum disorder (NMOSD) caused by AQP4 antibodies. It aims to see if these targeted therapies can help control the disease and prevent relapses.
Wuhan, HubeiAges 18–65 - NCT06882356Recruiting
AI eye screening for diabetic retinopathy
This study uses an AI-based system to check for diabetic retinopathy during regular eye exams at primary care clinics. It may help catch vision problems early if you have diabetes.
Boston, MassachusettsAges 40 years+ - NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT06563414Recruiting
A study tracking eye scrapes in people with DEB
This study follows people with dystrophic epidermolysis bullosa (DEB) who get scrapes on the surface of their eye (corneal abrasions). It collects information to better understand how often and how severely these eye injuries happen.
Pittsburgh, PennsylvaniaAges 6 months+ - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT06859515Recruiting
Long-term follow-up for wet AMD treatment
This study checks on the long-term safety and effects of a one-time treatment (EXG102-031) for wet age-related macular degeneration. It is only for people who already received that treatment in a previous study.
BeijingAges 50 years+ - NCT06859411Recruiting
Posterior corneal transplant study
This study looks at how well people do after a specific type of corneal transplant called posterior lamellar keratoplasty. It aims to understand long-term outcomes for patients who had this surgery.
MetzAges 18 years+ - NCT06864351Recruiting
Study of a new thyroid dosing method for children
This study tests a new way to adjust thyroid medication doses for children with either congenital hypothyroidism or Graves' disease. It aims to help find the right dose more easily and improve treatment outcomes.
YerevanAges Up to 18 years - NCT06859216Recruiting
Testing AI-made plain language summaries for eye clinic notes
This study tests whether using artificial intelligence (AI) to create easy-to-read summaries of your eye doctor's notes helps people better understand their eye care. If you are an English-speaking patient at the Jules Stein Eye Institute, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT04307238Recruiting
Anesthesia types and eye response after planned ENT surgery
This study compares different types of general anesthesia by checking how your pupils (the black part of the eye) respond after surgery. It may help doctors understand which anesthesia options are better for eye-related side effects after planned ear, nose, or throat operations.
Vienna, State of ViennaAges 18–99 - NCT06848946RecruitingPhase 4
Eye implant with cataract surgery vs. cataract surgery alone
This trial tests if a tiny implant called iDose® TR, placed during cataract surgery, can better control eye pressure in people with glaucoma or high eye pressure compared to cataract surgery alone.
Kenosha, WisconsinAges 45 years+ - NCT06850168Recruiting
Can special glasses slow down nearsightedness in children?
This trial tests a new type of spectacle lens designed to slow the progression of nearsightedness (myopia) in children. If your child is between 6 and 10 years old, has mild to moderate nearsightedness, and is willing to wear glasses full-time for two years, this study may be a good fit.
SingaporeAges 6–11 - NCT06847542RecruitingPhase 3
Study of a refillable eye implant for wet AMD
This trial tests a refillable eye implant (PDS) that slowly releases medication to treat wet age-related macular degeneration (nAMD). It aims to see if replacing the implant every 36 weeks works as well as regular eye injections.
InnsbruckAges 50 years+ - NCT06854393RecruitingPhase 2
Lacripep Eye Drops for Faster Healing After PRK
This study is testing a new eye drop called Lacripep to see if it helps heal the cornea (the clear front part of the eye) faster after PRK laser vision correction. It is for active-duty military members and their families who are already planning to have PRK surgery.
Fort Belvoir, VirginiaAges 21–55 - NCT06849908RecruitingPhase 2
Baricitinib for treating intestinal Behçet's disease
This trial tests baricitinib, an oral medication, for people with intestinal Behçet's disease that hasn't improved with standard treatments. It aims to see if baricitinib can reduce symptoms and help heal gut ulcers.
Beijing, Beijing MunicipalityAges 18–65 - NCT06854198Recruiting
Glaucoma screening for at-risk Californians
This study tests whether offering eye exams at a health center helps find glaucoma early in people who are at higher risk. It may help you catch vision problems before they get worse.
Fremont, CaliforniaAges 50 years+ - NCT06850571RecruitingPhase 4
Comparing two eye injections for diabetic macular edema
This trial compares two standard anti-VEGF injections (aflibercept and bevacizumab) for people with diabetic macular edema who have not recently had this treatment. The goal is to see which drug works better over three monthly doses to improve vision and reduce retinal swelling.
BaghdadAges 40 years+ - NCT06841575Recruiting
Better eye imaging for children and adults at Duke
This study tests a new camera that automatically adjusts to take clear pictures of the back of the eye. It aims to improve retinal imaging for healthy adults, adult eye clinic patients, and children seen at Duke Eye Center.
Durham, North CarolinaAges 1 month+ - NCT06841250Enrolling by invitation
Early eye changes after first injection for diabetic macular edema
This study looks at how the eyes of people with diabetes-related swelling in the retina change after their very first anti-VEGF injection. By measuring early changes in OCT scans, doctors hope to learn more about how well the treatment works and how to predict outcomes.
SohagAges Any age - NCT06843499Recruiting
AI eye screening for AMD and diabetic retinopathy
This trial tests an AI program called VeriSee that helps doctors check for eye problems like age-related macular degeneration (AMD) and diabetic retinopathy (DR). It compares the AI's accuracy and costs to standard care in regular eye clinics.
Taipei, TaiwanAges 20 years+ - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Birmingham, AlabamaAges 12 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Skin
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.