Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06948357RecruitingPhase 2
Eye drops for presbyopia in Chinese adults
This trial tests two eye drops, BRIMOCHOL PF and CARBACHOL PF, to see if they improve near vision in people with presbyopia (age-related difficulty seeing up close). The study is for Chinese adults aged 45-75 who have trouble reading even with glasses or contacts.
Wenzhou, ZhejiangAges 45–75 - NCT06949865Recruiting
AI-enhanced levodopa challenge test for parkinsonism
This study uses artificial intelligence (AI) to improve a standard test for parkinsonism called the levodopa challenge test. It may help doctors better understand how your movement symptoms respond to levodopa, a common Parkinson's medication.
BeijingAges 50–75 - NCT06952153Recruiting
Comparing two surgeries for glaucoma with cataract
This trial compares two types of eye surgery—one that removes the cataract and opens blocked drainage channels, and another that creates a new drainage pathway. It aims to find which works better for people with both glaucoma and cataracts.
Ho Chi Minh CityAges 40 years+ - NCT06952842RecruitingPhase 1/Phase 2
Gene therapy trial for retinitis pigmentosa with RHO mutation
This trial tests a new gene therapy called ZVS203e for people with retinitis pigmentosa caused by a specific RHO gene mutation. It aims to see if the treatment is safe and can help improve vision.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06953349Recruiting
Surgery systems with cataract and glaucoma treatment
This trial looks at how well certain surgical systems work when combined with cataract surgery and a glaucoma procedure. It may help people with glaucoma who need fewer medications after surgery.
Mesa, ArizonaAges 18 years+ - NCT06955611Recruiting
Is home monitoring safe for early diabetic eye problems?
This trial tests whether monitoring certain diabetic eye changes in the community is as safe as hospital checks. It's for people with early signs of diabetic eye disease that haven't yet reached a more advanced stage.
HaverfordwestAges 18 years+ - NCT06961357RecruitingPhase 1/Phase 2
CD40L-Enhanced TIL therapy for advanced melanoma
This trial tests a new way to treat advanced melanoma by taking immune cells from your tumor, enhancing them in the lab to fight better, and giving them back to you. It is for people whose melanoma has spread or cannot be removed, and who have already tried standard treatments.
Tampa, FloridaAges 18 years+ - NCT06961864Recruiting
Brain function in visual snow syndrome
This study uses visual tests and brain scans to understand how the brain processes vision in people with visual snow syndrome compared to those without. It may help researchers learn more about what causes this condition.
Minneapolis, MinnesotaAges 18–60 - NCT06963099Recruiting
INTACS for high astigmatism in healthy corneas
This trial tests a procedure called INTACS, which uses small plastic rings to reshape the cornea and reduce high astigmatism. It is for people whose corneas are healthy and not bulging or thinning.
SohagAges 18–60 - NCT06963203Recruiting
Surgery for hyperthyroidism from Graves' or amiodarone use
This study looks at thyroid removal surgery for hyperthyroidism caused by Graves' disease or the heart medication amiodarone. It aims to see how well the surgery works for these patients.
AalstAges 18 years+ - NCT06963684Recruiting
Glaucoma laser stability and sustainability study
This study tests whether a laser treatment helps keep eye pressure stable in people with early glaucoma or high eye pressure who have not used any eye drops or medications before. It may be a good option if you are looking for a treatment that doesn't require daily eye drops.
Coon Rapids, MinnesotaAges 40 years+ - NCT06964269RecruitingPhase 4
Acthar Gel for dry eye and autoimmune disease
This trial tests a new injectable medicine, Acthar Gel, for moderate to severe dry eye and eye pain linked to autoimmune disease. It aims to see if the drug can relieve these symptoms safely.
Nashville, TennesseeAges 18–85 - NCT06966167Recruiting
Laser vs. standard cataract surgery in Fuchs' dystrophy
This study compares two types of cataract surgery in people with Fuchs' dystrophy: one using a laser and the standard method. It looks at which approach gives better results for the cornea and vision.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06967792Recruiting
Safety of Terahertz Eye Scan for Blind Eyes
This trial tests a new scanning system that uses safe terahertz waves to look at the cornea. It's for people who are blind in one eye but have a healthy cornea, to see if the scan is safe.
Singapore, SingaporeAges 21 years+ - NCT06968611Recruiting
Diabetes and vision care study in Bangladesh
This study tests a program that combines diabetes care with eye exams for people in Bangladesh who were recently diagnosed with diabetes. The goal is to see if this approach helps you better manage your health and prevent vision problems.
DinajpurAges 30 years+ - NCT06968637Recruiting
Improving diabetes and vision care in Bangladesh
This study tests a new way to combine diabetes care with eye care for people with diabetes in Bangladesh. If you have diabetes and a diabetes-related eye condition, this might help improve your care.
Dinajpur Sadar, DinajpurAges 30 years+ - NCT06970236Recruiting
Strength training for eye melanoma survivors
This trial tests whether a high intensity resistance (strength) training program can help people who have been treated for choroidal melanoma (an eye cancer) with plaque brachytherapy. The goal is to improve muscle strength and overall health after cancer treatment.
Valencia, SpainAges 18 years+ - NCT06972602RecruitingEarly Phase 1
High-dose topotecan for retinoblastoma with vitreous seeds
This trial tests a high dose of a chemotherapy drug called topotecan given directly into the eye (intravitreal injection) for children with retinoblastoma that has come back or not responded to treatment and has seeds floating in the vitreous. The goal is to save the eye when removal is the only other option.
Shanghai, ChinaAges 1–12 - NCT06973278Recruiting
SMILE vs SMILE Xtra for high myopia
This study compares two types of laser eye surgery (SMILE and SMILE Xtra) to see which works better for people with high myopia. It aims to help you understand which option might give you the best vision correction.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT06976515Recruiting
Remote study for evaporative dry eye disease
This study tests if people with evaporative dry eye can monitor their condition from home using a smartphone app and mail-in tests. No treatment is given; the goal is to see if remote research is possible.
San Francisco, CaliforniaAges 18 years+ - NCT06979752Recruiting
Testing a new cannula for glaucoma-cataract surgery
This trial tests whether a special cannula can help protect the eye during combined surgery for pseudoexfoliative glaucoma (a type of glaucoma with flaky deposits) and cataracts. It may offer better results than standard irrigation.
AvranchesAges 18 years+ - NCT06982417Recruiting
RP2 Genetic Condition Registry
This registry study collects information from people who have a genetic change in the RP2 gene (a cause of inherited eye disease) and their families. It helps researchers learn more about the condition and how it affects daily life.
Göttingen, Lower SaxonyAges Any age - NCT06982807Recruiting
SMILE laser for stable nearsightedness
This study tests a new laser correction method called SMILE 4.0-VISULYZE to treat nearsightedness and other refractive errors. It may help people who are tired of glasses or contact lenses and want a quick, low-pain vision fix.
Nantong, JiangsuAges 18–40 - NCT06983652Recruiting
Validating a new scan for corneal scars and swelling
This study tests a new scanning technology (terahertz) to see if it can detect and measure corneal scars and swelling (edema). If you have one of these conditions, you may help validate a faster, non-invasive way to monitor your eye health.
SingaporeAges 21 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.