Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07063030RecruitingEarly Phase 1
Gene therapy trial for AIPL1-related eye disease
This trial tests a gene therapy called LX107 for people with vision loss caused by changes in the AIPL1 gene. It aims to see if the treatment is safe and can improve vision.
ShanghaiAges 4 years+ - NCT07063251RecruitingEarly Phase 1
Gene therapy safety study for Stargardt disease in teens
This study tests a new gene therapy called HG005 for Stargardt disease in young people aged 6 to 17. It aims to see if the treatment is safe and tolerable, and how well it works.
ShanghaiAges 6–17 - NCT07063537Recruiting
Virtual reality eye test for glaucoma patients
This trial tests whether a virtual reality device can accurately measure your field of vision compared to standard tests. If you have primary open-angle glaucoma and can perform a visual field test, you may be able to participate.
Halifax, Nova ScotiaAges 18 years+ - NCT07063875RecruitingPhase 1/Phase 2
Adding IL-2 to tebentafusp for advanced eye cancer
This trial tests if adding another drug called IL-2 to tebentafusp can help stop cancer from growing in people with advanced melanoma that started in the eye (uveal melanoma). It is for those whose cancer got worse while on tebentafusp alone.
Sydney, New South WalesAges 18 years+ - NCT07064759RecruitingPhase 3
Gene therapy injection for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (4D-150) for wet AMD. It might help reduce the need for frequent anti-VEGF eye injections by targeting the underlying cause of new blood vessel growth.
Scottsdale, ArizonaAges 50 years+ - NCT07065747Recruiting
Understanding inflammation in uveitis using advanced eye imaging
This study uses a special eye scan (OCT) to measure and classify inflammatory cells inside the eye. It aims to better understand different types of uveitis and improve diagnosis and treatment.
Portland, OregonAges 5–85 - NCT07069647Recruiting
AI screening for diabetic eye disease and macular degeneration
This trial tests if an AI tool can help detect diabetic retinopathy and age-related macular degeneration in older adults visiting family medicine or geriatric clinics. It aims to catch these eye conditions early, before they cause vision loss.
TaipeiAges 20 years+ - NCT07070037Recruiting
Long-term vision after congenital cataract surgery
This study looks at how good a child's vision and eye prescription are 5 years after surgery for a cataract they were born with. The goal is to understand long-term results and help guide care for future patients.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07070843Recruiting
Comparing two eye care methods for ICU patients on ventilators
This study compares two different ways of caring for the eyes of intensive care patients on breathing machines. It aims to find which method better prevents eye problems like dryness or infection.
Istanbul, IstanbulAges 3 weeks+ - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT07074431Recruiting
Comparing two methods for cataract surgery
This trial compares a new high-frequency pulsed vacuum technology to standard cataract surgery (phacoemulsification) for treating cataracts in both eyes. It aims to see which method works better and is safer for people with mild to moderate cataracts.
AmiensAges 18 years+ - NCT07075718RecruitingPhase 2/Phase 3
Evaluating a new travoprost eye implant for glaucoma
This trial tests a newer version of a tiny implant placed inside the eye to lower pressure in people with open-angle glaucoma or ocular hypertension. It may offer a treatment option that doesn't require daily eye drops.
Grand Junction, ColoradoAges 18 years+ - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT07077304Recruiting
Cardiac imaging study for inflammatory heart diseases
This study uses heart scans (MRI or nuclear imaging) to better understand inflammatory heart conditions. If you have a suspected inflammatory heart disease and are already scheduled for one of these scans, you may be able to join.
ParisAges 18 years+ - NCT07077967Recruiting
Light perception study for patients with special lens implants
This trial studies how well patients see light after getting a special kind of lens implant that helps with both near and far vision without glasses. It aims to understand how their eyes perceive brightness compared to normal vision.
Alexandroupoli, EvrosAges 45–75 - NCT07078799Recruiting
Comparing two types of LASIK for nearsightedness and astigmatism
This study compares two types of LASIK surgery to correct nearsightedness and astigmatism. It may help if you have healthy eyes, are 22 or older, and have a stable prescription within a certain range.
Palo Alto, CaliforniaAges 22–59 - NCT07080229RecruitingPhase 3
Nasal spray for blood pressure during cataract surgery in older adults
This trial tests whether a nasal spray of dexmedetomidine can help control blood pressure in older adults with high blood pressure who are having cataract surgery. It may keep your blood pressure more stable during the procedure.
Ismailia, Ismailia GovernorateAges 65 years+ - NCT07081919Recruiting
Study of laser-assisted cataract surgery outcomes
This study looks at how well femtosecond laser-assisted cataract surgery works and what factors affect its results. It may be a good option if you have age-related cataracts and regular astigmatism.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT07084844Recruiting
LASIK with advanced laser technology
This trial tests a new LASIK procedure using the WaveLight Plus laser. It aims to see how patients feel about their vision after surgery.
Houston, TexasAges 18–39 - NCT07084883Recruiting
AI system for early AMD detection
This trial tests an AI system designed to catch early signs of late age-related macular degeneration (AMD) before it's diagnosed. It's for people who haven't yet been diagnosed with AMD or treated for retinal disease.
Richmond Hill, New YorkAges 50 years+ - NCT07085533Recruiting
A Study of Inherited Retinal Diseases
This study is looking at how inherited retinal diseases affect color vision over time. It may help researchers understand these conditions better and is a good fit for people with a known diagnosis who can describe what they see.
WuhanAges Any age - NCT07085676RecruitingPhase 1
CAR-T cell therapy for autoimmune diseases that resist treatment
This study tests a new cell therapy called CAR-T (using your own immune cells) for people with severe autoimmune diseases like lupus, scleroderma, or myositis that have not improved with standard treatments. The goal is to see if it can safely reduce disease activity.
JerusalemAges 18–80 - NCT07091825Recruiting
Lubricating drops for rigid gas permeable contact lens wearers
This trial tests a new lubricating eye drop for people who wear rigid gas permeable (RGP) contact lenses. The drops are meant to make wearing the lenses more comfortable and less dry.
Beijing, Beijing MunicipalityAges 8 years+ - NCT07092124Recruiting
Virtual reality test for low vision rehabilitation
This study is testing a virtual reality test to help people with low vision who are starting or have started rehabilitation. The goal is to see how well the test works for different types of vision loss.
AngersAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.