Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06737562Recruiting
Same-day vs separate-day cataract surgery: a cost study
This study compares having cataract surgery in both eyes on the same day versus a few weeks apart. It aims to find out which approach is more cost-effective and convenient for patients like you.
BrestAges 18 years+ - NCT06737354Enrolling by invitationPhase 1
Study of IVB103 injection for wet age-related macular degeneration
This trial tests a new treatment called IVB103 for people with wet age-related macular degeneration (AMD). It aims to see if the injection is safe and effective for those who have already had anti-VEGF therapy. You may qualify if you have active disease and have had at least two prior anti-VEGF treatments.
Chengdu, SichuanAges 50 years+ - NCT06727604RecruitingPhase 2
Study of IMVT-1402 for Graves' disease not controlled by medication
This trial tests a new drug called IMVT-1402 for adults with Graves' disease whose thyroid is still overactive despite taking antithyroid medication. The goal is to see if the drug can safely help control thyroid hormone levels.
Phoenix, ArizonaAges 18–75 - NCT06731582Enrolling by invitationPhase 3
Nicotinamide supplement study for glaucoma patients
This trial tests whether a vitamin B3 supplement called nicotinamide can help slow down vision loss in people with glaucoma. It is for those with moderate disease who are already on treatment.
Singapore, Central SingaporeAges 21 years+ - NCT06723106Enrolling by invitationPhase 1
Long-term safety study of RAY121 for immune conditions
This study is for people who already took RAY121 in a previous trial and did well. It tests whether continuing the treatment is safe and effective over a longer period. The goal is to manage chronic immune conditions.
Camperdown, New South WalesAges 18–85 - NCT06717412Recruiting
Low-dose conbercept for retinopathy of prematurity
This trial tests whether a low dose of conbercept, given as an eye injection, can safely treat type 1 ROP (an eye disease in premature babies). The goal is to stop abnormal blood vessel growth and prevent vision loss.
Xi'an, ShaanxiAges Any age - NCT06725173Recruiting
Retinoblastoma genetics and tumor spread study
This study looks at gene changes in retinoblastoma to understand why some tumors spread outside the eye. It may help find better ways to predict and treat the disease.
Seattle, WashingtonAges Any age - NCT06719739Recruiting
Special lens implant for cataract patients with epiretinal membrane
This study tests a special intraocular lens (IOL) implanted during cataract surgery in people who also have epiretinal membrane (ERM), a thin layer of scar-like tissue on the retina. The goal is to see if this lens works well and safely for their eyes.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06035887Recruiting
New eye test for hydroxychloroquine damage
This trial tests a new type of eye test (ERG) to detect early damage from hydroxychloroquine, a drug used for conditions like lupus and rheumatoid arthritis. If you take hydroxychloroquine or have never taken it, you might help find better ways to protect your vision.
London, LondonAges 18 years+ - NCT05749094Recruiting
Ultrasound of the optic nerve in new suspected giant eye artery disease
This trial studies whether a quick ultrasound of the optic nerve (plus an eye exam) can help evaluate new suspected giant cell arteritis (GCA). It may help doctors assess eye risk early and decide on the best next steps.
London, OntarioAges 50–99 - NCT06709339RecruitingPhase 4
Study of faricimab for Caucasian patients with polypoidal choroidal vasculopathy
This trial tests a drug called faricimab for a type of wet age-related macular degeneration called polypoidal choroidal vasculopathy (PCV). It aims to see if the drug is safe, works well, and how long the effects last in patients who have not been treated before.
MilanAges 50–90 - NCT06694272Recruiting
Visual function tests for early age-related macular degeneration
This study looks at how well the eyes function in people with early or intermediate age-related macular degeneration (AMD). It uses imaging and vision tests to help doctors better understand the condition.
ParisAges 18 years+ - NCT06701721RecruitingPhase 1
Study of THN391 eye injection for diabetic macular edema
This trial tests an experimental eye injection called THN391 for people with diabetic macular edema, a condition that causes vision loss due to swelling in the back of the eye. The study aims to see if the treatment is safe and may help improve vision.
Parramatta, New South WalesAges 18–80 - NCT06701617Recruiting
Vision training for children with low vision
This study tests two types of vision training for children with low vision, either in person or through telehealth. It aims to help improve how children use their remaining vision.
TaipeiAges 1 month–18 years - NCT06693882Enrolling by invitation
Electrical stimulation for glaucoma
This study tests if mild electrical stimulation of the optic nerve can help people with moderate to advanced glaucoma. It may be an option if your glaucoma has gotten worse despite standard treatments.
San Francisco, CaliforniaAges 18 years+ - NCT06693856Enrolling by invitation
Steroid pulse therapy for active Graves' eye disease
This study tests whether high-dose steroid pulses (given through a vein) can help people with moderate to severe Graves' eye disease that is still active. It is for people who have not yet been treated with steroids and whose eye problems began within the past year.
Shanghai, Shanghai MunicipalityAges 25–70 - NCT03115710Recruiting
Study to map eye conditions in children and teens
This study looks at how common certain eye conditions are in children and teens who are visiting a clinic for a reason unrelated to eye problems. It may help doctors understand how often these issues occur and plan better screening and care.
Los Angeles, CaliforniaAges 6–23 - NCT06682819Recruiting
Looking at eye nerve layers in NOHL gene carriers
This study uses a special eye scan (OCT) to look at the layer of nerve fibers in the retina of people who carry (or don't carry) a specific gene change linked to Leber Hereditary Optic Neuropathy (NOHL). The goal is to find early warning signs in the blood that might show who is at risk of losing vision.
Paris, ParisAges 18–60 - NCT06684522RecruitingEarly Phase 1
Upadacitinib for stubborn eyelid dermatitis
This study tests if the medication upadacitinib can help people whose eyelid rash has not improved with prescription creams. It's for adults who have had eyelid dermatitis for at least two months and have tried at least one prescribed cream that didn't work.
Chicago, IllinoisAges 18–70 - NCT06685328Enrolling by invitation
Minimal surgery with gel for macular hole
This study tests a new, less-invasive surgery for macular holes. The surgeon uses a tiny gel to help close the hole without removing as much gel-like fluid from your eye as usual. It may help your vision recover with less risk.
Chengdu, SichuanAges 18 years+ - NCT06682455Enrolling by invitation
Predicting AMD progression with advanced scans and AI
This study is looking at people with intermediate AMD who previously took part in the PINNACLE study. It will use advanced eye scans and machine learning to learn more about how AMD progresses and how to predict it.
ViennaAges Any age - NCT06685211Recruiting
Electrical stimulation for vision in glaucoma
This trial tests whether gentle electrical stimulation can help improve vision in people with moderate vision loss from glaucoma. It might offer a new way to strengthen remaining vision.
Palo Alto, CaliforniaAges 18 years+ - NCT06689397Enrolling by invitation
Study of Epstein-Barr virus-related pink eye
This trial is studying a specific type of eye infection (pink eye) caused by the Epstein-Barr virus. It aims to better understand the condition and may help guide treatment for people with these symptoms.
LondonAges 16 years+ - NCT06682962Recruiting
Electrical stimulation for vision loss from glaucoma
This trial tests if a gentle electrical stimulation on the eye can slow or improve vision loss in people with open-angle glaucoma. It uses a device you can use at home after training.
MainzAges 40 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.