Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06049459Recruiting
Virtual Reality Games for Lazy Eye in Kids
This study tests if playing virtual reality games can help improve vision in children with lazy eye (amblyopia). It may be an option for kids who haven't fully improved with glasses or patching.
Columbus, OhioAges 5–17 - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT06782997Recruiting
Using a quick eye test to check for diabetes eye damage
This trial tests if a special eye exam (electroretinogram) done by a nurse can find early signs of diabetic retinopathy in people with diabetes who have no known eye problems yet. It aims to make screening easier and more accessible.
ReimsAges 18 years+ - NCT05966493RecruitingPhase 2
Lufepirsen gel for persistent corneal epithelial defects
This Phase 2 trial tests whether a treatment gel called NEXAGON (lufepirsen) can improve healing and safety in people with a persistent corneal problem called PCED that hasn’t gotten better despite standard non-surgical treatments. You may be a candidate if your defect has lasted at least 2 weeks and hasn’t improved recently, and if you don’t have certain eye infections or other eye conditions.
Dothan, AlabamaAges 2 years+ - NCT06780462RecruitingPhase 3
Steroids with or without blood thinners for Behçet's vein clots
This trial tests whether adding a blood thinner (anticoagulant) to steroid therapy is more effective than steroids alone for treating deep vein thrombosis (a blood clot in a large vein) in people with Behçet's syndrome. It aims to find the best way to prevent future clots and reduce side effects.
BordeauxAges 18 years+ - NCT06249438RecruitingPhase 1
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new CAR-T cell therapy (C-CAR168) for people with several autoimmune diseases that have not responded to standard treatments. It aims to see if this therapy can control the disease when other medicines have failed.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+ - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT06765980RecruitingPhase 1/Phase 2
Study of KRIYA-825 for geographic atrophy in age-related macular degeneration
This trial tests an experimental drug called KRIYA-825 (also known as VV-14295) for people with geographic atrophy, a late stage of dry age-related macular degeneration that causes vision loss. The study aims to see if the treatment is safe and can help slow the progression of the disease.
Erie, PennsylvaniaAges 55–80 - NCT06763731RecruitingPhase 4
Optimizing the eye surface with Systane COMPLETE before cataract surgery
This study tests whether using Systane COMPLETE eye drops before cataract surgery can improve the eye surface in people with dry eye. If you have dry eye and are scheduled for cataract surgery, this trial may help improve your eye comfort and surgery outcomes.
Taipei, TaiwanAges 20–85 - NCT06000865Recruiting
Video game and exercise rehab for glaucoma
This trial tests if active video games and exercise can help people with glaucoma improve their balance and daily function. It's for people who have stable vision loss and can still walk independently.
Hong Kong, Hong KongAges 55–80 - NCT06751615Enrolling by invitation
Improving scleral lens fit with advanced imaging
This study tests whether using advanced imaging can help make scleral contact lenses fit better for people with certain eye conditions. If you have keratoconus, an irregular cornea after a transplant, or severe dry eye and have struggled with other lens types, this may be for you.
MadridAges 18 years+ - NCT06753916RecruitingPhase 2
Trial of a new treatment for high-risk cornea transplants
This study tests a new approach to help prevent cornea transplant failure in people with high-risk conditions, such as blood vessels growing into the cornea. It aims to see if this treatment can improve transplant success.
Irvine, CaliforniaAges 18 years+ - NCT06760169Recruiting
Laser combined with cataract and glaucoma surgery
This study tests a new laser device (ELIOS) during combined cataract and glaucoma surgery. It may help people who need both cataract removal and glaucoma treatment, aiming to lower eye pressure safely.
AvranchesAges 18–80 - NCT06755060Recruiting
AI-assisted eye care study
This trial tests how artificial intelligence can help doctors make better decisions about eye diseases. It may be a good fit if you have an eye condition and can share your medical records and images.
Zhuhai, GuangdongAges Any age - NCT00313677Recruiting
Trial readiness for dystroglycan-related muscle conditions
This trial is for people who have signs that they may have a dystroglycanopathy—a group of muscle conditions. It helps study how ready participants are for care and possibly future treatments by using lab and genetic/pathology information to confirm the condition.
Iowa City, IowaAges Any age - NCT05809635Recruiting
Study for BEST1-related macular eye disease
This trial is studying people with BEST1-associated vitelliform macular dystrophy, a genetic eye condition affecting central vision. It will involve several eye-related study visits over about three years, aiming to better understand the condition and how it is managed.
New York, New YorkAges Any age - NCT06742307RecruitingPhase 4
Faricimab quarterly shots for wet age-related macular degeneration
This trial tests if faricimab eye injections given every 3 months can keep wet age-related macular degeneration under control. It is for people with a new or returning active blood vessel growth in the center of the macula.
Hong KongAges 50 years+ - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Avondale, ArizonaAges 18 years+ - NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT06744478Enrolling by invitation
Misight contact lenses for children with different vision between eyes
This trial tests whether Misight 1 Day contact lenses can help children and young adults whose eyes have different prescriptions (anisometropia). It looks at how much the vision difference changes over 24 months of wearing the lenses.
Hualien CityAges 8–23 - NCT06745375Enrolling by invitation
Soft contact lens fit and power study
This study looks at how soft contact lenses fit on the eye and how their power affects vision. It may help you if you wear or want to try soft contact lenses.
Birmingham, UKAges 18–60 - NCT06740162Recruiting
Physical activity program for adults with intellectual disabilities
This study tests a program to help adults with intellectual disabilities become more physically active. You and your caregiver will work with a coach to increase your daily movement, with the goal of improving health and community connection.
Fayetteville, ArkansasAges 18 years+ - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.