Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06683651RecruitingPhase 3
Study of a treatment for droopy eyelid in Chinese patients
This study tests a new treatment for Chinese patients whose droopy upper eyelid (acquired blepharoptosis) seriously affects their vision. It may help if your eyelid droops low enough to block part of your sight and you haven't had previous corrective surgery or certain eye conditions.
Hefei, AnhuiAges 18–75 - NCT06344572Recruiting
Study of SAT-001 for children with nearsightedness
This trial tests a device called SAT-001 to slow down nearsightedness (myopia) in children aged 5 to 9. It might help if your child has mild to moderate nearsightedness with low astigmatism.
IncheonAges 5–8 - NCT05037370Recruiting
Compare two eye laser procedures for vision correction
This study compares two types of laser surgery for vision problems (PRK versus another approach called “WFO ablation”) to see which works better for clear sight. You may be a candidate if you meet specific eye measurements and can return for follow-up visits.
San Antonio, TexasAges 21–50 - NCT06672536RecruitingPhase 1/Phase 2
Study of SCT520FF for wet age-related macular degeneration
This trial tests an investigational drug called SCT520FF for people with wet age-related macular degeneration (nAMD). It aims to find the safest dose and check if it can improve vision. You may be eligible if you have active new blood vessels in your eye from nAMD and have not had certain other eye problems.
TianjingAges 45–80 - NCT06679634RecruitingPhase 2
Topotecan eye patch for retinoblastoma
This trial tests a new way to deliver the chemotherapy drug topotecan directly to the eye (via a small patch placed on the eye surface) for children with retinoblastoma that either needs eye removal or has come back after standard treatment. It aims to see if this approach can help save the eye and vision.
New York, New YorkAges Up to 8 years - NCT06680037RecruitingPhase 1
Azer-cel therapy for immune-related neurological diseases
This trial is testing an experimental cell therapy called azer-cel for people with certain autoimmune diseases that affect the nervous system. The therapy aims to reduce immune attacks on the body by targeting and removing faulty B cells.
La Jolla, CaliforniaAges 18 years+ - NCT06669728Recruiting
ICL eye surgery prediction study using eye images
This study tests if a computer model can look at images of your eye to help predict whether ICL surgery (a type of vision correction) will work well. It may help find the best lens size for people with nearsightedness.
Nanchang, JiangxiAges 18–45 - NCT05668455RecruitingPhase 3
Topical treatments for irritated eyes with an eye prosthesis
This Phase 3 study compares two topical (applied to the eye) treatments to reduce inflammation-related irritation in people who wear a permanent eye prosthesis. It may help if your prosthesis-related eye discomfort is ongoing despite basic care like artificial tears.
RennesAges 18–85 - NCT06659549RecruitingPhase 2
Eye drop treatment for advanced dry AMD with geographic atrophy
This trial tests a daily eye drop (GAL-101) to see if it can slow the growth of geographic atrophy lesions in people with dry age-related macular degeneration (AMD) when the center of the macula is not yet involved.
Beverly Hills, CaliforniaAges 55 years+ - NCT06662162Recruiting
Microcurrent therapy for dry age-related macular degeneration
This trial tests a new type of electrical stimulation, called microcurrent therapy, to see if it can help people with a certain form of age-related macular degeneration (AMD) that is not the "wet" kind. The treatment is delivered through an eye patch-like device and may slow vision loss or improve function.
Poway, CaliforniaAges 60 years+ - NCT06659445RecruitingPhase 2
Study of ONL1204 for geographic atrophy in dry AMD
This study tests an investigational medicine called ONL1204 given as an injection into the eye for people with a form of advanced dry age-related macular degeneration called geographic atrophy. The goal is to see if it can slow vision loss.
Gilbert, ArizonaAges 55 years+ - NCT06662448Recruiting
Light stimulation for nerve damage in the eye
This study tests if a gentle electrical current, like a light flicker, can help people with optic neuropathy (damage to the nerve connecting the eye to the brain). You would attend 30 sessions over 8 weeks. It might improve your vision if you still have some sight left.
New York, New YorkAges 18 years+ - NCT06658002RecruitingPhase 3
Testing stronger eye drops for fungal eye infections
This trial tests if adding cyclosporine A to the standard natamycin eye drops can better treat fungal eye infections. It may help people with moderate vision loss from a fungal corneal infection.
San Francisco, CaliforniaAges 18 years+ - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06649799Enrolling by invitation
Comparing two lasers for cataract surgery in older adults
This study tests two different femtosecond lasers (LenSx and Z8) used during cataract surgery to see how they affect the eye's natural response, including inflammation and pupil size. It is designed for adults over 50 with age-related cataracts of moderate hardness.
Hangzhou, ZhejiangAges 50–80 - NCT06650358Enrolling by invitation
Outcomes for patients with LAL+ lens implants
This study looks at how the LAL+ lens implant performs in people who have had cataract surgery in both eyes and have completed light adjustments for the LAL+ lens. It aims to gather information on vision results and safety.
Wilkes-Barre, PennsylvaniaAges Any age - NCT06647641Recruiting
Genetics study for PSP, CBS, MSA, and related conditions
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
Boston, MassachusettsAges 35 years+ - NCT06651736Recruiting
Low vision rehab for people with inherited eye disease and distress
This study tests a 10-week low vision rehabilitation program for people with inherited retinal diseases who also feel emotionally distressed. The goal is to see if the program improves daily function and emotional well-being.
Ann Arbor, MichiganAges 18 years+ - NCT05487989Recruiting
Visual pathway study for recent optic neuritis
This study looks at how the eye-to-brain visual pathways work in people who have had optic neuritis symptoms for less than 4 weeks. It may help researchers better understand neuro-inflammatory (nerve inflammation) disorders and improve future care.
LilleAges 18–65 - NCT06644196Recruiting
Building an eye image database with new laser technology
This study uses a special laser to take detailed images of the eye. It aims to create a database that could help doctors better understand and diagnose eye conditions like glaucoma, macular degeneration, and retinal diseases.
ParisAges 18 years+ - NCT06635148RecruitingPhase 2/Phase 3
Long-term study for geographic atrophy treatment
This study is for people who already took part in a previous trial for geographic atrophy (a late stage of dry age-related macular degeneration) and received the study drug or a sham. It looks at the long-term safety of the treatment over time.
Tucson, ArizonaAges 60 years+ - NCT06643884RecruitingPhase 2
Study of eye treatment for cancer that has spread to the eye
This trial tests a new way to treat cancer that has spread to the back of the eye (choroid). The treatment is given directly into the eye, which may help control the tumor and preserve vision.
Palo Alto, CaliforniaAges 18 years+ - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT06636019Enrolling by invitation
Contact lens for nearsightedness and eye thickness
This trial tests whether a special contact lens can slow down nearsightedness by measuring changes in the thickness of the back layer of your eye. It may help you understand if this lens works for your vision.
AugsburgAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.