Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT03288948Recruiting
Binocular game therapy for lazy eye
This study tests a treatment that uses both eyes together (binocular games) to improve vision in children with “lazy eye” (amblyopia). It may help the weaker eye work better while the child practices at home and during study visits.
Dallas, TexasAges 4–10 - NCT06246149RecruitingPhase 3
Tebentafusp after treatment for high-risk eye melanoma
This trial tests a new drug called tebentafusp given after standard treatment (surgery or radiation) for high-risk uveal melanoma that hasn't spread. The goal is to see if it helps prevent the cancer from coming back.
Lake Success, New YorkAges 18 years+ - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07676981RecruitingPhase 2
Atropine eye drops for watery eyes
This study tests whether atropine eye drops can reduce excessive tearing (watery eyes) caused by various reasons. If you have watery eyes that bother you daily, these drops might help by decreasing tear production.
Houston, TexasAges 18 years+ - NCT07565103RecruitingPhase 1/Phase 2
Testing SUM-191 eye drops for bacterial pink eye
This trial tests a new eye medication called SUM-191 for treating bacterial conjunctivitis (a bacterial infection that causes pink eye). The study has three parts: first testing safety in healthy people, then in people with the infection itself.
Austin, TexasAges 18 years+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT02422875Enrolling by invitation
Study of immune markers in autoimmune disease and lupus
This study looks at blood and immune cell markers (autoantibodies and immune cell “signatures”) to better understand autoimmune conditions, including lupus. It may help researchers identify which markers are linked to disease and how immune cells respond after vaccination.
Atlanta, GeorgiaAges 18 years+ - NCT02402660Enrolling by invitationPhase 2
Test ALK-001 for Stargardt disease eye changes and comfort
This Phase 2 study tests how well ALK-001 is tolerated and whether it can slow or improve vision-related changes in people with Stargardt disease. It mainly looks at safety (tolerability) and signs in the eye over about 24 months.
Phoenix, ArizonaAges 8–70 - NCT00341874Enrolling by invitation
Genetic study of deafness in Pakistani families
This study looks at genetic causes of deafness by comparing affected and unaffected family members. It may help researchers understand why some people are born or develop deafness and guide future diagnosis for families in Pakistan.
LahoreAges 2 years+ - NCT00313677Recruiting
Trial readiness for dystroglycan-related muscle conditions
This trial is for people who have signs that they may have a dystroglycanopathy—a group of muscle conditions. It helps study how ready participants are for care and possibly future treatments by using lab and genetic/pathology information to confirm the condition.
Iowa City, IowaAges Any age - NCT01195558Recruiting
Registry survey for people who are blind and have sleep problems
This study is a registry survey that collects information about sleep problems and daytime sleepiness. It may help researchers better understand sleep issues in people who are blind and plan future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT01746537Recruiting
Eye imaging test in people with uveitis
This study uses a special eye scan (optical coherence tomography) to look at inflammation in the front part of the eye. It may help doctors better measure uveitis activity and guide care by improving how inflammation is seen on scans.
Cleveland, OhioAges Any age - NCT01654159Enrolling by invitation
Study of vision and lens optics during cataract surgery
This study looks at how well your vision works and how different cataract surgery lens choices perform. It may help researchers better understand what affects sight after cataract surgery.
Birmingham, West MidlandsAges 40–85 - NCT07400224RecruitingPhase 1/Phase 2
New PET imaging test for cancer, heart, or immune disease
This study tests a new type of PET scan using a special tracer called Al18F-NOTA-FAPI-04 to see if it can better detect cancer, heart disease, or immune system conditions. The goal is to find out how well this imaging method works for diagnosis or monitoring of these diseases.
BeijingAges 18–88 - NCT07400757Recruiting
Statin and vitamin D for active thyroid eye disease
This trial tests whether a statin (a cholesterol-lowering medicine) combined with vitamin D can improve active thyroid eye disease. It may help if you have both eye inflammation and high cholesterol.
Taipei, TaiwanAges 20 years+ - NCT07400926Recruiting
Study of a new inserter for a glaucoma implant
This trial is testing a new way to deliver a medication (travoprost) directly into the eye using a small implant. It's for people with open-angle glaucoma and aims to see how well the updated inserter works.
Kenosha, WisconsinAges 18 years+ - NCT07400952RecruitingPhase 2
Testing GLK-221 Eye Drops for Keratoconus
This study tests an eye drop called GLK-221 for people with keratoconus, a condition where the clear front of the eye bulges. The goal is to see if the drops can safely help improve the condition compared to a placebo (an inactive solution).
Westerville, OhioAges 18–55 - NCT07403825RecruitingPhase 4
Faricimab for wet AMD with subretinal material
This trial tests a new drug called Faricimab for people with a specific type of wet age-related macular degeneration (AMD) that has a buildup of material beneath the retina. The goal is to see if Faricimab can help clear this material and improve vision.
Córdoba, AndalusiaAges 50 years+ - NCT07408154Recruiting
Direct vs standard laser for glaucoma: which works better?
This study compares a direct laser treatment to the standard laser for glaucoma or high eye pressure. It aims to see if the direct method is just as effective and possibly safer.
Charleston, South CarolinaAges 18 years+ - NCT07409077Recruiting
Biofeedback training for glaucoma patients
This study tests if biofeedback training—a technique that helps you learn to use your remaining vision better—can improve vision in people with glaucoma. It focuses on those with vision loss near the center of their sight.
Toronto, OntarioAges Any age - NCT07410039RecruitingPhase 4
Acute treatment for neuromyelitis optica in real-world setting
This study looks at treatments for people with neuromyelitis optica spectrum disorder (NMOSD) who are having a sudden attack affecting their vision or spinal cord. It aims to find out which treatments work best in everyday practice.
BeijingAges 18–65 - NCT07410637Recruiting
Thyroid hormones and energy in graves' or thyroid cancer
This trial studies how thyroid hormone levels affect your body's use of sugar and energy. It may help people newly diagnosed with Graves' disease or thyroid cancer understand their metabolism better.
Ulm, Baden-WurttembergAges Any age - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.