Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06320431RecruitingPhase 3
Clot-busting drug for disabling stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Sydney, BarangarooAges 18 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT06322030Recruiting
Weight loss and exercise for stroke survivors
This study tests whether a weight loss and exercise program can help veterans who had a stroke at least 6 months ago and have some leg weakness. It aims to improve mobility and overall health.
Charleston, South CarolinaAges 40–80 - NCT06322056Recruiting
Lower blood pressure and cholesterol targets for advanced kidney disease
This trial tests whether keeping blood pressure and cholesterol at lower-than-usual levels can help slow the decline of kidney function in people with advanced chronic kidney disease. If you have moderately to severely reduced kidney function and meet certain blood pressure and cholesterol criteria, you may be able to join.
SeoulAges 19 years+ - NCT06322953RecruitingPhase 3
Timing to restart blood thinners after head injury bleeding
This trial looks at when it is safest to restart blood thinners after a traumatic brain bleed. It compares restarting at 4 weeks versus 8 weeks in people on blood thinners before their injury.
Plymouth, DevonAges 18 years+ - NCT06323018Recruiting
Remote preconditioning for cemented hip replacement recovery
This trial tests whether a simple, safe treatment called remote ischemic preconditioning (using a blood pressure cuff on your arm just before surgery) can help people recover better after cemented hip replacement. It is for patients aged 66 and older who are scheduled for this surgery.
Tartu, TartuAges 65–90 - NCT06323434Recruiting
Spinal fluid leaks in chronic subdural hematoma
This study looks for spinal fluid leaks in people with chronic subdural hematoma (a slow buildup of blood on the brain). It uses MRI to find a possible cause, which could help improve treatment.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Birmingham, AlabamaAges 18 years+ - NCT06324188Recruiting
Early ablation for afib to prevent stroke in high-risk patients
This trial tests whether an early procedure (catheter ablation) for atrial fibrillation (AF) can prevent strokes in people with a high risk of stroke. The goal is to see if this treatment is safer and more effective than standard care for patients with other health conditions.
Multiple LocationsAges 18 years+ - NCT06325384Recruiting
Testing a contactless blood pressure monitor for home use
This trial tests a new, no-contact device called Lifelight that measures your blood pressure just by looking at your face. It compares these readings to the standard cuff method, and you can use it at home for self-monitoring.
LondonAges 18–100 - NCT06325371Recruiting
Study of a Stent for Visceral Artery Aneurysms
This trial tests a special stent called Derivo to treat aneurysms in arteries of the abdomen. It aims to see if this device safely blocks blood flow to the aneurysm and helps prevent rupture.
Torino, TOAges 18 years+ - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT06324981Recruiting
AI text messages to help your heart health
This study tests if text messages from an AI program can help you improve your heart health habits, like taking medication on time and managing blood pressure, cholesterol, or diabetes.
Denver, ColoradoAges 18–89 - NCT06325280Recruiting
Exercise MRI for Kids with Heart Conditions
This study uses an MRI while exercising to check heart and lung fitness in children with heart disease. It helps doctors learn more about how to care for kids who have had a heart transplant or were born with heart problems.
Edmonton, AlbertaAges 10–18 - NCT06325488Recruiting
Kidney Health Study in Fabry Disease
This study uses MRI scans to look at how Fabry disease affects the kidneys, including scarring, swelling, and oxygen levels. It may help researchers understand kidney problems better and find new ways to monitor the disease.
CopenhagenAges 18 years+ - NCT06325618Recruiting
Studying lymphedema and blood vessels in Turner syndrome
This study looks at swelling (lymphedema), inflammation, and blood vessels in women with Turner syndrome. It uses MRI scans to understand these issues better.
Aarhus NAges 18–100 - NCT06333327Recruiting
Atrial fibrillation ablation with a balloon catheter registry
This study is collecting data on people having a procedure called catheter ablation for atrial fibrillation using a special radiofrequency balloon. The goal is to see how well it works and to help improve future treatments.
BrusselsAges 18–85 - NCT07042529Recruiting
Optimizing valve placement during TAVI
This trial is testing a better way to position a new heart valve during a TAVI procedure. The goal is to help the valve work as well as possible for people with severe aortic stenosis.
AalstAges 18 years+ - NCT07291817Recruiting
Negative pressure treatment for diabetic foot ulcers
This trial tests a device that uses gentle suction (negative pressure) to help heal diabetic foot ulcers. It may help people with poor blood flow in their legs who have not healed with other treatments.
SingaporeAges 21–99 - NCT06033950RecruitingPhase 3
A study of finerenone for heart failure patients who can't take standard MRA drugs
This study tests whether finerenone, a new type of drug, can help people with heart failure who cannot take standard steroid-based MRAs (a kind of heart medication) because of side effects or other reasons. It aims to see if it improves symptoms and is safe for you.
Fairhope, AlabamaAges 18 years+ - NCT07360158Recruiting
Studying a new implantable heart device (ICD) for heart patients
This study is testing a new type of implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) called the CorSky Family. The goal is to see how well it works for people who need a device to help their heart pump properly and prevent dangerous rhythms.
Graz, StyriaAges 18–99 - NCT06174727Recruiting
Registry of flow diverter and disruptor treatments
This study is a registry that collects information from patients who have had a brain aneurysm treated with a special type of device called a flow diverter or flow disruptor. By joining, you help doctors learn more about how well these treatments work over time and which patients benefit most.
Coral Gables, FloridaAges 18 years+ - NCT05400824Recruiting
Health study in La Réunion
This study looks at how metabolism and infections affect people in La Réunion. Participants will provide consent for genetic analysis and answer health questions.
La Réunion, Saint-PierreAges 18–67
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.