Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06453538Recruiting
Sleep and breathing in bypass surgery patients
This study looks at how well patients sleep and if they have breathing problems during sleep before and after heart bypass surgery. It may help understand how sleep affects recovery.
TurkuAges 18–90 - NCT06453850Recruiting
New catheter for pacemaker lead placement in the septum
This trial tests a new thin tube (catheter) used to guide a pacing wire into the wall between the heart's lower chambers, called the septum. It may be a good option if you need a first-time pacemaker or CRT-D implant and your heart's pumping function is fairly good.
CoimbraAges 18 years+ - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT06455488Recruiting
Ventricular tachycardia management outcomes registry
This registry collects information about how ventricular tachycardia (a fast heart rhythm from the lower chambers) is managed and the results of different treatments. Participating can help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06455514RecruitingPhase 1
Magnesium to protect the brain after cardiac arrest
This study tests if giving magnesium soon after a cardiac arrest can protect the brain and improve recovery. It is for adults who have been brought back to life after a heart stoppage.
New York, New YorkAges 18–85 - NCT06455644Recruiting
CT vs. X-ray for sizing heart device in AF treatment
This study tests whether using a CT scan or a special X-ray (DSA) is better for picking the right size of a left atrial appendage closure device during a combined ablation and closure procedure. It aims to make the procedure safer and more effective.
Foshan, GuangdongAges 18 years+ - NCT06455787Recruiting
J-Valve study for leaky aortic valve patients
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
Scottsdale, ArizonaAges 18 years+ - NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06456437Recruiting
Testing a new technique after clot removal for stroke
This trial tests if a special technique called 'ischemic post-conditioning' can improve recovery after a large vessel stroke. It is for people who have had a major blockage in a brain artery that was successfully opened with a clot retrieval procedure.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06456814Recruiting
Study on how brain aneurysms form, grow, and rupture
This study looks at medical records from multiple hospitals in China to understand how brain aneurysms develop and when they might rupture. It may help researchers find better ways to predict and treat them.
GuangzhouAges 18–80 - NCT06457217Recruiting
MRSI for minor stroke with large artery blockage
This study uses a special MRI technique (called MRSI) to look at brain chemistry in people who have had a minor stroke due to a blocked large artery. The goal is to see if the scan can help doctors better understand the stroke and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06457386Recruiting
Echocardiogram vs no echocardiogram for low-risk Staph blood infection
This study compares two approaches for people with a blood infection caused by Staphylococcus aureus who are at low risk for heart infection (VIRSTA score <3). Half of the participants will get a standard echocardiogram (heart ultrasound), and the other half will not, to see if skipping the test is safe and effective.
ParisAges 18 years+ - NCT06458088Recruiting
Sugar-related substances and blood vessel problems in type 1 diabetes
This study looks at how certain sugar-related substances in the blood (called advanced glycation products) are linked to blood vessel problems in people with type 1 diabetes. It follows up with participants from an earlier study at Reims Hospital.
ReimsAges 18 years+ - NCT06458153Recruiting
Imaging speech after cerebellar stroke
This study uses brain scans to understand how the brain controls speech in people who have had a cerebellar stroke. It is looking for both stroke survivors and healthy volunteers to compare.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06459336Recruiting
Comparing two therapies for arm function after stroke
This study tests two different schedules of Constraint-Induced Movement Therapy (CI therapy) to see which better helps stroke survivors regain use of their weaker arm and hand. You may qualify if you can make small wrist and finger movements.
Lahore, Punjab ProvinceAges 45–65 - NCT06459388Recruiting
Balance training methods for stroke recovery
This study compares two types of physical therapy exercises to help stroke survivors improve balance and walking. One method uses arm and leg movements, while the other focuses on the pelvis area.
Lahore, Punjab ProvinceAges 40–65 - NCT06459934Recruiting
Heart and cardiovascular disease study
This study looks at the health outcomes of people with common heart conditions like coronary artery disease, high blood pressure, heart failure, or cardiomyopathy. It may help researchers understand how these conditions progress and how to better manage them.
Ürümqi, XinjiangAges 18–80 - NCT06460142Recruiting
Biomarker study for giant cell arteritis and polymyalgia rheumatica
This study is looking for biomarkers (biological clues) in people with newly diagnosed or flaring giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Participating may help researchers find better ways to diagnose and monitor these conditions.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06461962Recruiting
Peer support for meth-related heart screening
This study tests whether a peer support program can help people who use methamphetamine get screened for early heart damage. It aims to connect you with care if screening shows possible heart strain.
Portland, OregonAges 18 years+ - NCT06462274Recruiting
Blood and brain markers for brain bleed recovery
This study looks for markers in your blood and brain scans that may help doctors better understand and predict outcomes after a spontaneous brain bleed. It is for people with high blood pressure who have had a bleed within the last three days.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06462768Recruiting
Study of immune cell activity in systemic sclerosis
This study looks at a specific type of immune cell activity (called neutrophil extracellular traps) in the blood of people with systemic sclerosis, other connective tissue diseases, and healthy volunteers. It aims to understand how these cells may be involved in the disease and could lead to better treatments.
ReimsAges 18 years+ - NCT06463717Recruiting
Stem cell transplant timing for multiple myeloma with no cancer cells left
This trial looks at people with newly diagnosed multiple myeloma who have no detectable cancer cells after initial treatment. It aims to see if these patients can do well without a stem cell transplant or with a delayed one, reducing unnecessary side effects.
Hangzhou, ZhejiangAges 18–70 - NCT06463808Recruiting
Heart recovery after heart attack with added protein therapy
This trial tests if adding a protein called rhBNP (which helps the heart relax) to standard care after a heart attack and stent improves heart recovery and pumping strength over time.
Nanjing, JiangsuAges 18–75 - NCT06464042Recruiting
Air Quality and Early Heart Disease Study
This trial studies how air quality affects early heart disease in young adults aged 18 to 40. It looks at people in Galicia, Spain, who already have coronary artery disease and compares them to healthy individuals.
Vigo, PontevedraAges 18–40
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.