Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06464588RecruitingPhase 1
Testing safety of newborn stem cells for dilated cardiomyopathy in young adults and children
This study tests whether a single intravenous infusion of stem cells from donated newborn tissue is safe for people aged 4 to 39 with dilated cardiomyopathy (a weakened, enlarged heart). It aims to find a new option for those who haven't improved enough with standard heart failure medications.
Atlanta, GeorgiaAges 4–40 - NCT06464991RecruitingPhase 3
Eque-cel for Lenalidomide-Refractory Multiple Myeloma
This study tests a new CAR-T cell therapy called Eque-cel for people with multiple myeloma that no longer responds to lenalidomide. It aims to see if this treatment can help control the disease after 1-2 prior therapies.
BeijingAges 18–75 - NCT06465043Recruiting
Understanding Heart Failure When the Heart Stiffens
This study is for people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't relax well. It aims to better understand heart failure through advanced testing, and it includes people who are newly diagnosed or have had a recent hospitalization.
HelsinkiAges 18–85 - NCT06465303RecruitingPhase 2
Study of RTP-026 for heart attack patients
This trial tests a new medicine called RTP-026 for people having a serious heart attack (STEMI). It looks at whether the medicine is safe and helps the heart recover better when given along with the standard procedure to open the blocked artery.
CopenhagenAges 18–85 - NCT06465316RecruitingPhase 1
Teclistamab plus iberdomide for relapsed multiple myeloma
This trial tests a combination of two drugs, teclistamab and iberdomide, for people with multiple myeloma that has come back or stopped responding to at least 4 prior treatments. The goal is to see if this combination can work when other options have failed.
Phoenix, ArizonaAges 18 years+ - NCT06465459Recruiting
Testing the LAMBRE device for left atrial appendage closure
This study is testing a device called LAMBRE that is used to close a small pocket in the heart (the left atrial appendage). The goal is to see how well it works in everyday medical practice for people who need this closure procedure.
PessacAges 18 years+ - NCT06465719Recruiting
Robot-assisted surgery for moderate brain bleeding
This trial tests if a minimally invasive surgery guided by a robotic AI system can help people with moderate bleeding deep inside the brain (basal ganglia). If you qualify, the surgery would happen within 72 hours of your stroke.
Hangzhou, ZhejiangAges 18 years+ - NCT06465758Recruiting
Stroke recovery study
This study is for people who have had a stroke and are in the early recovery phase. It looks at how well patients recover, with a focus on arm and hand movement, to help guide future care.
MilanAges 18 years+ - NCT06466161Recruiting
Testing a new blood pressure measurement method in pregnant patients
This study is testing a new way to measure blood pressure on your forearm and upper arm. It aims to see if this method works well for pregnant patients, especially those with high blood pressure conditions.
Chicago, IllinoisAges 18 years+ - NCT06466772Recruiting
Personalized walking therapy after stroke
This study tests a new therapy that uses personalized electrical stimulation to help people who have trouble walking after a stroke or brain bleed. It aims to improve how your brain and muscles work together for better walking.
Zurich, Canton of ZurichAges 18 years+ - NCT06466980Recruiting
Study of ventilator-related events after cardiac arrest
This study looks at lung-related problems that can happen when someone is on a breathing machine after surviving a cardiac arrest. If you qualify, researchers will track your recovery to better understand how to prevent these complications.
Corbeil-EssonnesAges 18 years+ - NCT06467513RecruitingPhase 4
Esketamine for lung problems after heart valve surgery
This study tests whether a medicine called esketamine can help prevent lung problems after heart valve surgery. If you are having valve replacement or repair with a heart-lung machine, you may be able to join.
Zunyi, GuizhouAges 18–75 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Birmingham, AlabamaAges 14–35 - NCT06468774Recruiting
Test for gut ischemia in chronic belly artery disease
This study tests a blood marker for chronic mesenteric ischemia (poor blood flow to the gut). If it works, it could help doctors diagnose the condition faster and more easily.
Oslo, OsloAges 18 years+ - NCT06469918Recruiting
Support community for congenital heart defects
This trial is for people affected by congenital heart defects. It offers a support community (Co-Op) to help you connect, share, and get resources.
Rochester, MinnesotaAges birth+ - NCT06471127Recruiting
Brain changes after stroke that causes language problems
This study looks at how the brain rewires itself after a stroke that causes aphasia (language problems). It uses brain scans to understand changes in brain networks, which may help improve recovery treatments.
Madison, WisconsinAges 40–90 - NCT06471621Recruiting
Personalized care to prevent kidney injury after heart surgery
This trial tests whether personalized care can prevent acute kidney injury (sudden kidney damage) after heart or major blood vessel surgery. If you are having planned heart valve repair, bypass, or aortic surgery, you may be able to join.
BernAges 18 years+ - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06472414Recruiting
Heart rehab program designed for women
This study tests a heart rehab program designed just for women. It aims to help women stick with rehab, get stronger, and feel better. You may be eligible if you have a stable heart condition and are ready to exercise.
LisbonAges 18 years+ - NCT06472934Recruiting
Beta-blockers & TAVR study
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
GrazAges 18 years+ - NCT06472986Recruiting
Activity-based therapy with spinal stimulation for spinal cord injury
This study tests whether combining activity-based therapy (exercises to improve arm and hand function) with a mild electrical stimulation on the skin of your back can help people with chronic neck-level spinal cord injury regain more arm and hand movement.
Toronto, OntarioAges 18 years+ - NCT06473207Recruiting
Can a blood pressure cuff protect the brain after cardiac arrest?
This trial tests if a special blood pressure cuff (like a tourniquet) placed on the leg can protect the brain after a cardiac arrest. It is for patients who are unconscious and on a breathing machine after their heart restarts.
Toulon, VarAges 18 years+ - NCT06473272Recruiting
Ultrasound to study neck artery plaques and predict risk
This study uses different ultrasound techniques to look at plaques in the neck artery and predict future heart or stroke events. It may help doctors understand which plaques are more dangerous.
Shanghai, Shanghai MunicipalityAges 40–100 - NCT06473389Recruiting
A treatment for shoulder pain after stroke
This trial tests a treatment called suprascapular radiofrequency ablation (a targeted heat procedure) to help relieve shoulder pain after a stroke. It is for people who have had a stroke at least 3 months ago and still have severe shoulder pain.
Ankara, YenimahalleAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.