Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06536686Recruiting
Heart check during abdominal surgery study
This study checks for silent heart problems in people having abdominal surgery for non-cancer reasons. It aims to see if patients with a silent heart attack during surgery can be identified and helped.
LjubljanaAges 18 years+ - NCT06537583Recruiting
Ear stimulation after a STEMI heart attack
This study tests whether gentle electrical stimulation near your ear (tragus) can help stabilize your heart's rhythm and reduce inflammation after a STEMI heart attack. It may help lower the risk of future heart problems.
Semarang, Central of JavaAges 18–70 - NCT06538155Recruiting
Using smartwatch data to predict cardiac arrest
This trial uses data from smartwatches and smartphones to better predict and recognize cardiac arrest. If you are a healthy volunteer or have had a heart event, your device data could help improve emergency care.
MilanAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+ - NCT06538571Recruiting
Infant heart study using light to check oxygen levels
This study uses a light-based sensor placed on the skin to measure oxygen levels in infants with a single heart ventricle before their Glenn surgery. The goal is to see if these measurements can help predict how well they do between surgeries.
Oak Lawn, IllinoisAges Up to 6 months - NCT06538454Recruiting
Strength training for high blood pressure in postmenopausal women
This study tests whether different levels of resistance (strength) training can help improve heart health in women with high blood pressure who have gone through menopause. It may help you safely lower your blood pressure.
Ribeirão Preto, São PauloAges 50–65 - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT06539026Recruiting
Fluid therapy guided by vein ultrasound in preeclampsia
This trial is testing a way to give fluids before C-section to women with severe preeclampsia. It uses an ultrasound measure of the big vein in your belly (the inferior vena cava) to help decide how much fluid is safe, which may reduce complications.
Cairo, EgyptAges Any age - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age - NCT06539234Recruiting
Testing angiotensin II for vasoplegic shock
This trial gives a drug called angiotensin II to people in vasoplegic shock (a type of shock where blood vessels stay too relaxed despite other medicines). It tests how the drug affects a kidney-related hormone (renin) and if it can help raise blood pressure.
MariborAges 18 years+ - NCT06539624Recruiting
Testing a new gene therapy for Fabry disease
This trial is testing a new treatment called EXG110 for people with Fabry disease. It's designed to see if it's safe and if it can help. You may be able to join if you have a confirmed diagnosis and at least one symptom of Fabry disease.
Shanghai, Shanghai MunicipalityAges 7 years+ - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT06539832Recruiting
Gut bacteria and immunity in people with an abnormal blood protein
This study looks at how your gut bacteria (intestinal flora) and immune system relate to a condition called monoclonal gammopathy, where an abnormal protein is found in the blood. The trial will check samples from your blood, plasma, and stool to understand these connections.
Guanzhou, GuangdongAges 45 years+ - NCT06540521Recruiting
Heart device holter study for LBBAP patients
This study uses a special wearable device to record your heart's electrical signals. It is for people who have a pacemaker or CRT-P with a specific type of lead (LBBAP) and wants to check how well the therapy is working.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06541132Recruiting
Liver fat and heart artery narrowing study
This study looks at whether the amount of fat in your liver, seen on an ultrasound, is linked to the severity of narrowing in your heart arteries. If you had a heart catheterization (angiography) and an abdominal ultrasound, your data may help researchers understand this connection.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT06541353Recruiting
Predicting heart function after a pulmonary embolism
This study uses heart signals and blood tests to predict how well your heart will recover over a year after a pulmonary embolism. It may help doctors tailor your care based on your personal risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06541509RecruitingPhase 1/Phase 2
Semaglutide for heart failure in overweight patients
This trial studies whether the drug semaglutide can help people with heart failure who are overweight. It aims to see if the drug improves heart function and symptoms.
Palo Alto, CaliforniaAges 20–80 - NCT06541860Recruiting
Study of daratumumab and lenalidomide for resistant multiple myeloma
This trial tests a combination of two drugs, daratumumab and lenalidomide, for patients with multiple myeloma that has not responded to previous treatments. It aims to see if this regimen can help when other therapies have stopped working.
Pavia, PVAges 18 years+ - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT06542263Recruiting
CPAP for preventing AF recurrence after ablation in people with AF and sleep apnea
This study tests whether using a CPAP machine at night can help prevent atrial fibrillation from coming back after a heart procedure called catheter ablation. It is for people who have both AF and moderate to severe obstructive sleep apnea.
Suzhou, JinagsuAges 18 years+ - NCT06542393RecruitingPhase 2
Blood management for anemic patients having bypass surgery
This trial tests a blood management strategy to help people with anemia who are having coronary artery bypass surgery (CABG). If you qualify, you may receive a treatment to improve your blood counts before surgery, which could reduce the need for transfusions.
São Paulo, São PauloAges 18–80 - NCT06542653Recruiting
PCI for chronic heart artery blockages
This trial looks at how a procedure to open a long-clogged heart artery (called PCI) affects patients' long-term health. If you have had a complete blockage in a heart artery but no recent major heart attack, bypass surgery, or cancer, you may be able to join.
Nanjing, JiangsuAges 18–75 - NCT06542770Recruiting
Predicting hidden atrial fibrillation after cryptogenic stroke
This trial uses a small heart monitor to see if certain heart changes can predict hidden atrial fibrillation in people who had a stroke or mini-stroke with no clear cause. It aims to find those who might benefit from blood thinners to prevent another stroke.
BarcelonaAges 50–89
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.