Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06822400Recruiting
Study of Tetralogy of Fallot in Newborns
This trial looks at newborns with Tetralogy of Fallot, a heart condition present at birth. It aims to study the best way to treat these babies in the first month of life.
Beijing, Beijing MunicipalityAges 1 minute–6 months - NCT06822439Recruiting
Remote fetal monitoring for high-risk pregnancies
This study tests if remote monitoring of your baby's heartbeat from home is a safe and effective option for high-risk pregnancies. It may reduce the need for frequent hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06822894Recruiting
3-vessel ultrasound flow study in heart disease patients
This trial uses a special ultrasound to measure blood flow in three main heart arteries. It may help doctors better understand blockages and improve treatment planning.
BeijingAges 18 years+ - NCT06822972RecruitingPhase 2
Study of Selinexor Plus Bispecific Antibody for Resistant Myeloma
This study tests the drug selinexor in combination with a bispecific antibody for multiple myeloma that has already been treated with at least 4 prior therapies. The goal is to see if the combination is safe and effective for patients whose disease has returned or hasn’t responded to previous treatments.
Durham, North CarolinaAges 18 years+ - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT06823570Recruiting
Exercise and blood pressure medicine for better blood vessels
This study is testing whether a combination of blood pressure medication and a supervised exercise program can improve the health of your blood vessels. It's for people with mild to moderate high blood pressure who are not already on medication.
Düsseldorf, DüsseldorfAges 18 years+ - NCT06825104Recruiting
Long-term comparison of two ablation methods for persistent AF
This long-term study follows people who already completed a 12-month study comparing two types of heart ablation for persistent atrial fibrillation. It looks at how well the treatments worked over time.
BronAges 18 years+ - NCT06825897Recruiting
Direct to angiography suite for stroke clot removal
This trial compares two ways to treat severe stroke patients with a large vessel blockage. One way is the standard approach of first imaging you and then deciding. The other way takes you directly to the angiography suite for immediate clot removal by the doctor. The goal is to see if this faster, direct approach helps you get better results.
Iowa City, IowaAges 18 years+ - NCT06826339RecruitingPhase 4
Advanced wound treatments for diabetic foot and leg ulcers
This study compares several advanced wound treatments (called CAMPs) plus standard care to standard care alone for hard-to-heal diabetic foot ulcers and venous leg ulcers. It aims to see if the extra treatments help wounds close faster and prevent complications.
Monroeville, PennsylvaniaAges 21 years+ - NCT06826872RecruitingPhase 2
Testing SPC1001 for essential hypertension
This trial tests an oral medication called SPC1001 to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure not caused by another condition). It may help if you have mild to moderate high blood pressure.
SeoulAges 19–75 - NCT06826963Recruiting
Eccentric exercise for older adults with heart failure and muscle loss
This study tests whether a special type of exercise (eccentric, or lengthening, exercises) can help older adults with heart failure who also have muscle loss. It aims to see if the exercise is safe and improves strength and function.
Verona, VeronaAges 65–85 - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+ - NCT06827314Recruiting
Treating cardiogenic shock with drug and mechanical support
This trial is testing different approaches (medications and mechanical support) to help people with acute heart failure and cardiogenic shock (a sudden drop in the heart's pumping ability). It looks at how well these treatments work in a network of hospitals to improve outcomes.
Bologna, BolognaAges 18 years+ - NCT06827652Recruiting
Triple-A Barcelona: A study for abdominal aortic aneurysms
This study is testing a new approach to manage abdominal aortic aneurysms (bulges in the main belly artery). It is for people whose aneurysm is larger than 30 mm but does not have certain rare features that require different care.
Barcelona, CataloniaAges 18 years+ - NCT06827860RecruitingPhase 2
Talquetamab shot for elderly with relapsed multiple myeloma
This study tests a new drug called talquetamab, given as a shot under the skin, for older adults with multiple myeloma that has come back or stopped responding to earlier treatments. The goal is to see if it can help control the cancer with fewer side effects.
New York, New YorkAges 70 years+ - NCT06828042RecruitingPhase 1/Phase 2
CAR-γδT cells for refractory autoimmune diseases
This trial tests a new type of immune cell therapy (CAR-γδT cells) that targets a protein called CD19 on your own B cells. It is for people with certain autoimmune diseases that have not gotten better with standard treatments. The goal is to see if this therapy can safely control the disease.
BeijingAges 18–80 - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06828679Recruiting
AI system to improve arm recovery after stroke
This trial tests whether an AI-powered system can help improve arm movement in people who had a stroke 1 to 6 months ago. It uses electrical stimulation to activate muscles and may lead to better recovery.
Hong Kong, Sha TinAges 65–80 - NCT06828770Recruiting
Minima stent system long-term safety study
This study checks the safety of the Minima Stent System over time. It is for people who need a stent to keep their blood vessel open. The study wants to see how the device works in real-world use.
Los Angeles, CaliforniaAges Any age - NCT06828692Recruiting
Using computer tools to find the best blood pressure medicine for you
This trial tests a computer program that helps doctors choose the most suitable blood pressure medicine for each person. If you have high blood pressure and are taking none or two types of medication, this study may help find a better treatment plan.
Shenzhen, ShenzhenAges 35–79 - NCT06829134Recruiting
Kidney nerve block for high blood pressure during surgery
This trial tests if numbing the nerves around the kidney artery during laparoscopic surgery can better control high blood pressure. It is for people already needing surgery for certain kidney or adrenal conditions who also have hypertension.
ShanghaiAges 18–75 - NCT06829212Recruiting
Wireless brain implant for device control
This trial tests a wireless brain implant that lets you control external devices like a computer or wheelchair just by thinking. It's designed for people with paralysis or double arm amputations who want to regain some independence.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06829420Recruiting
Mirroring speech to help people with aphasia talk better
This study tests a new way to help people who have trouble speaking after a stroke by having them mirror and follow along with recorded phrases. It is for adults who had a stroke on the left side of their brain and now have nonfluent aphasia (trouble getting words out).
Tampa, FloridaAges 18–70 - NCT06830499Recruiting
Sapien 3 valve for younger Chinese patients with severe aortic stenosis
This trial tests a newer artificial heart valve (Sapien 3) placed through a small tube in the leg, for younger people (50–70) with severe aortic stenosis. It aims to see if this less invasive option works well in this age group.
Xi'an, ShaanxiAges 50–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.