Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06830512Recruiting
Ultrasound-guided radiofrequency ablation for heart tumors
This trial tests a procedure that uses ultrasound images to guide a thin needle into the heart to destroy tumors with heat. It is for people who have heart tumors causing symptoms but cannot have standard surgery.
Xi'an, ShannxiAges Any age - NCT06830785Recruiting
Rhythmic sound therapy for chronic stroke recovery
This study tests if rhythmic sounds (like clapping) can help improve arm movement in people who had a stroke at least six months ago. It focuses on those with mild to moderate arm weakness and no major hearing problems.
TaipeiAges 18 years+ - NCT06831409Recruiting
Heart scan study for retired NFL players
This trial uses heart CT scans to measure plaque and blood flow in retired NFL players, helping understand heart risks.
Greenwood Village, ColoradoAges Any age - NCT06831500RecruitingPhase 1/Phase 2
Study on carbidopa/levodopa ratio for low blood pressure in MSA-P and Parkinson's
This study tests whether adjusting the ratio of carbidopa and levodopa (medications used for Parkinson's) can help reduce dizziness or fainting from low blood pressure when standing up, in people with Multiple System Atrophy (Parkinsonian type) or Parkinson's disease.
Lausanne, Canton of VaudAges Any age - NCT06831474RecruitingPhase 1
Rivaroxaban in breast milk after childbirth
This study looks at how a blood thinner called rivaroxaban enters breast milk after delivery. It may help women who need this medication while breastfeeding.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT06831890Recruiting
Smartphone heart risk check study
This study sees if a smartphone app can safely estimate your heart risk without a doctor visit. It's for people who don't have heart disease or diabetes and can use their own phone.
BernAges 40–69 - NCT06832033Recruiting
Exercise program after atrial fibrillation ablation
This trial is testing whether a structured exercise program (combining cardio and strength training) can help people who have already had a procedure to treat atrial fibrillation. It aims to see if this type of training can improve heart health and quality of life.
Zaragoza, ZaragozaAges 18 years+ - NCT06832787Recruiting
Negative pressure therapy for diabetic foot wounds
This study tests whether combining negative pressure wound therapy (a special dressing that uses gentle suction) can help diabetic foot wounds heal better after toe amputation. It is looking for people who have had their big or little toe removed and have adequate blood flow to the foot.
SingaporeAges 21–100 - NCT06832839Recruiting
Cognitive impairment in moyamoya disease study
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
Beijing, ChinaAges 18–60 - NCT06832865RecruitingPhase 2
Elranatamab and isatuximab for relapsed multiple myeloma
This trial tests a combination of two drugs—elranatamab and isatuximab—for people with multiple myeloma that has come back or stopped responding to at least two prior treatments. The goal is to see if this new combination can help control the disease.
Boston, MassachusettsAges 18 years+ - NCT06833476Recruiting
EVOQUE device trial for severe tricuspid regurgitation
This study looks at how well the EVOQUE device works for people with Medicare who have severe tricuspid regurgitation (a leaky heart valve) or who might get the device. It helps doctors learn more about treating this condition.
Irvine, CaliforniaAges 65 years+ - NCT06834230RecruitingPhase 4
Testing dotinurad for high uric acid in people with high blood pressure
This study tests a medicine called dotinurad to see if it helps lower high uric acid levels in people who also have high blood pressure. It may be an option if you have not taken uric acid lowering drugs recently or have been off them for over 27 days.
Saga, Saga-kenAges 20 years+ - NCT06834607Recruiting
Modified Stent Graft for Complex Abdominal Aneurysm
This trial tests a doctor-modified stent graft for treating complex aneurysms near the kidneys. It may be an option if your aneurysm is too complicated for standard devices and you are healthy enough for the procedure.
Hartford, ConnecticutAges 18 years+ - NCT06835491RecruitingPhase 3
Amiodarone to prevent heart rhythm problems after cardiac arrest
This trial tests whether giving the drug amiodarone early can prevent dangerous heart rhythm problems in patients who survived a cardiac arrest with a shockable rhythm. If it works, it could help more people recover.
AmiensAges 18 years+ - NCT06835959Recruiting
Moms at Home: A story-based app to manage blood pressure in pregnancy
This study tests if using a storytelling app on your smartphone can help you better manage your blood pressure during pregnancy. You would share your blood pressure readings at home and use the app as part of your care.
Worcester, MassachusettsAges 18–50 - NCT06835946Recruiting
How anesthesia and imaging affect heart valve leak assessment
This study looks at how anesthesia, breathing machines, and imaging methods change the way doctors measure a leaky heart valve. It aims to make sure the severity of aortic regurgitation is accurately measured before surgery.
LiègeAges 18 years+ - NCT06836011Recruiting
Heart valve leakage study in a type of amyloid heart disease
This study looks at how common and how serious heart valve leaks are in people with transthyretin amyloid cardiomyopathy (a condition where abnormal protein builds up in the heart). The goal is to better understand these leaks and how they affect long-term health.
Graz, StyriaAges 18 years+ - NCT06836232RecruitingPhase 2
Study of VTX2735 for recurring pericarditis
This trial tests an experimental drug called VTX2735 for people with recurring pericarditis (inflammation around the heart). It aims to see if the drug can help reduce pain and inflammation during a flare-up.
Tucson, ArizonaAges 18–75 - NCT06836830Recruiting
Comparing Two Ventilator Settings After Cardiac Arrest
This study compares two ways of setting the breathing machine for people who suffer a cardiac arrest outside the hospital. It looks at whether using a small amount of extra pressure (called PEEP) improves outcomes compared to using no extra pressure (ZEEP).
Gütersloh, North Rhine-WestphaliaAges 18 years+ - NCT06837311Recruiting
Smoking cessation after stroke via smartphone monitoring
This study tests a smartphone-based program that helps people who recently had a stroke quit smoking. It uses digital monitoring and support as part of your regular post-stroke follow-up to lower the risk of another stroke.
BordeauxAges 18–80 - NCT06838013Recruiting
Electrical stimulation to improve leg movement after stroke
This trial tests a new way to help people with stroke move their legs better by combining electrical stimulation on the back and leg. If you have had a stroke more than 6 months ago and can already walk with or without a cane, this treatment might help strengthen ankle muscles and make walking easier.
Hong KongAges 50–85 - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06838637Recruiting
Spinal cord stimulation at home for blood pressure issues
This trial tests using a gentle electrical device on your spine at home to help with dizziness from low blood pressure (orthostatic hypotension). It is for people with chronic spinal cord injury or multiple system atrophy who live in British Columbia.
Vancouver, British ColumbiaAges 19–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.