Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06556407Recruiting
Kidney nerve treatment for high blood pressure in dialysis patients
This trial tests a procedure called renal denervation (using radio waves to calm overactive nerves in the kidney) to see if it helps lower blood pressure in people on dialysis who have resistant high blood pressure.
Erlangen, BavariaAges 18–99 - NCT07508865Recruiting
Sustainable anesthesia for heart bypass surgery
This trial studies a sustainable anesthesia approach for people having planned coronary artery bypass graft surgery (a type of open-heart surgery to improve blood flow to the heart). It aims to see if this method is safe and effective for patients at the study hospital.
Temuco, AraucaniaAges 18 years+ - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT07471867RecruitingPhase 4
Testing a new stomach medicine for heart patients on clopidogrel
This trial tests if a new stomach acid medicine (Zastaprazan) affects how well clopidogrel works in heart patients who have had a stent placed. It aims to help people who need both clopidogrel and a stomach acid drug after a procedure.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT07528144Recruiting
Exoskeleton vs. Lead Apron for Surgeon Protection During Aortic Repair
This study compares a new exoskeleton device (a wearable support system) to standard lead aprons for protecting surgeons from radiation during endovascular aortic repair procedures—a minimally invasive surgery to fix problems in the main artery in the abdomen. The trial tests whether the exoskeleton provides better protection and comfort.
Szczecin, West Pomeranian VoivodeshipAges 35 years+ - NCT06233318Recruiting
Pain block for open heart surgery recovery
This study tests a nerve block given during open heart surgery to improve pain control. It might help patients recover with less discomfort.
Columbus, OhioAges 18 years+ - NCT06090890RecruitingPhase 4
Anti-inflammatory therapy for repeated stent blockages
This trial tests if anti-inflammatory drugs like prednisone or colchicine can prevent stents from blocking again in people who have already had multiple stent blockages. It may offer a new treatment option for those with recurrent in-stent restenosis.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07020286Enrolling by invitation
Prince of Wales Hospital structural heart registry
This trial is a registry that collects information on people who have procedures for structural heart problems at Prince of Wales Hospital. It helps researchers study outcomes and improve future care.
Hong Kong, ShatinAges 18–90 - NCT06460519Recruiting
Comparing wrist and groin blood pressure in shock patients
This study looks at how blood pressure readings differ between the wrist and the groin in people with severe low blood pressure (shock) who are not recovering from heart surgery. It aims to help doctors better understand and treat shock by comparing these two measurements.
BronAges 18–99 - NCT06650501RecruitingPhase 4
Comparing two blood thinners for staph bloodstream infections
This study compares two types of blood thinners (dabigatran vs. a common Xa inhibitor like apixaban) in people with a staph infection in their blood. The goal is to see which is safer and works better.
Montreal, QuebecAges 18 years+ - NCT07462546Recruiting
Ultrasound monitoring during carotid artery stenting
This trial is testing a special ultrasound (called transcranial Doppler) to monitor blood flow during a procedure to open a narrowed carotid artery in your neck. The ultrasound helps doctors see if the procedure is safe and working well.
ShenyangAges 40 years+ - NCT07406412Recruiting
Hormones and heart health before and after ovary removal
This study looks at how hormones affect heart health and metabolism in women who are having their ovaries removed (for non-cancer reasons). It will help researchers understand the changes that happen after surgery and how to better manage health during this transition.
HelsinkiAges 35–50 - NCT06460571Recruiting
Exercise after heart stent: with or without Delorme technique
This trial compares two types of cardiac rehab exercises for people age 70+ who recently got their first heart stent. It aims to see if adding progressive resisted exercises (the Delorme technique) helps improve breathing and recovery.
Sialkot, Punjab ProvinceAges 70–80 - NCT07458191Recruiting
Apixaban safety and adherence for atrial fibrillation patients
This trial tests how well patients with atrial fibrillation take their apixaban medication and whether it is safe. It aims to see if using apixaban for the first time works well without causing bleeding problems.
SarajevoAges 18 years+ - NCT04388124RecruitingPhase 2
Test drug to block endothelin for hard-to-control blood pressure
This Phase 2 trial tests whether blocking endothelin (using bosentan and related treatments) can improve blood pressure in people with resistant hypertension—high blood pressure that stays high despite multiple medicines. It may help if your blood pressure is still above target even with the right combination of therapy.
RouenAges 18–80 - NCT06454955RecruitingEarly Phase 1
PET scan imaging study for solid tumors using a new probe
This trial tests a new imaging agent that targets a protein called B7-H3 found on many solid tumors. It uses PET/CT to help doctors see and stage tumors more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT07454564Recruiting
Heart function and surgery risk in older adults
This study looks at how well the heart pumps blood to predict recovery after abdominal surgery in people 65 and older. It uses an ultrasound of the heart (echocardiogram) to measure heart power and a standard score to estimate surgical risk.
KonyaAges 65 years+ - NCT06964100Recruiting
How Heart Rate During Training Affects Your Endurance
This study looks at how your heart rate changes during training to help improve your endurance. If you run a 5K regularly and wear a compatible activity tracker, you may help researchers understand what top performance looks like.
Chicago, IllinoisAges 18–65 - NCT07452250RecruitingPhase 2
Ferumoxytol-enhanced MRI for vein problems
This trial uses a special iron-based contrast agent called ferumoxytol during an MRI scan to get clearer pictures of your veins. It's for people who may have vein blockages or other vein issues that need better imaging.
Nanjing, JiangsuAges 18 years+ - NCT07450222Enrolling by invitation
Improving high blood pressure care
This trial studies a new way to help people with high blood pressure get better control of their numbers. It uses a team approach to support you in managing your blood pressure and lowering your risk for heart problems.
Peoria, IllinoisAges 18 years+ - NCT06979427Recruiting
Predicting heart artery blockages with CT and FFR
This study tests whether a CT scan combined with blood-flow measurements can better predict which heart artery blockages are serious. It may help avoid unnecessary invasive tests.
Shiraz, FarsAges 20–80 - NCT07448623RecruitingPhase 1
Testing coramitug for ATTR amyloid heart disease
This study tests a new medication called coramitug to see if it can reduce abnormal protein deposits in the heart. You will have special PET/CT scans to measure how the drug affects these deposits.
GroningenAges 60 years+ - NCT05835349Recruiting
Study of Venus P-Valve for lung valve problems
This observational study follows people who need a pulmonary valve treatment, to see how the Venus P-Valve works in real-world care. It may help doctors understand which patients benefit and how outcomes change over time.
Pessac, New AquitaineAges 12–70 - NCT06445660Recruiting
Using CT scans to find salvageable bowel in mesenteric ischemia
This trial is testing a new way to use CT scans to identify which parts of the bowel can still be saved in patients with acute mesenteric ischemia. It aims to help doctors make better decisions about whether surgery is needed.
TartuAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.