Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07766135Recruiting
Liver and blood clotting in heart amyloidosis
This study looks at how the liver and blood clotting are affected in people with a type of heart disease called transthyretin amyloidosis. It may help doctors better understand and manage this condition.
Messina, SicilyAges 18 years+ - NCT07759427Recruiting
Using a new mapping method to guide treatment for fast heartbeats after a heart attack
This study tests a new way to find the exact spot in the heart that causes rapid heartbeats, so doctors can treat it more precisely with a procedure called catheter ablation.
BrightonAges 18 years+ - NCT07764172Recruiting
Sarcopenia in acute ischemic stroke
This study looks at muscle loss (sarcopenia) in people who have had an acute ischemic stroke. It aims to understand how muscle wasting affects recovery, which may help improve care for stroke patients.
MoscowAges 50 years+ - NCT06405594Recruiting
Studying sentence production in aphasia
This study looks at how people with aphasia (language trouble after a stroke) produce sentences, compared to healthy adults. By understanding these brain processes, researchers hope to improve language recovery strategies.
College Park, MarylandAges 18 years+ - NCT06581562RecruitingPhase 1
Testing rituximab plus AB-101 for autoimmune diseases
This trial tests a new treatment (AB-101) combined with rituximab for people with certain autoimmune diseases like rheumatoid arthritis, pemphigus vulgaris, vasculitis, or lupus. It is for those who have not had success with standard therapies.
Plantation, FloridaAges 18 years+ - NCT06584266Recruiting
Cardiac imaging registry for atrial fibrillation
This study collects data from heart imaging tests (TEE) in people with atrial fibrillation or atrial flutter. It aims to better understand how these imaging results relate to treatment decisions and outcomes.
BrnoAges 18 years+ - NCT03559114RecruitingPhase 3
Preventing blood clots after severe brain injury
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Calgary, AlbertaAges 18 years+ - NCT06584565Recruiting
Predicting stroke recovery and risk using blood and stool tests
This study uses advanced analysis of your blood and stool samples to better predict how you will recover from a stroke and whether it might happen again. It aims to help doctors personalize your care after a stroke.
Guangzhou, GuangdongAges 18–75 - NCT02061787Recruiting
Exercise testing to assess outcomes in pulmonary hypertension
This trial studies how well a treadmill/breathing exercise test can measure health outcomes in people with certain types of pulmonary hypertension. It may help your care team judge your status and track changes over time.
BeijingAges 5–100 - NCT04521790Recruiting
Biopsy-guided treatment for suspected inflammation of the heart
This study looks at people 18 and older with suspected myocarditis (inflammation of the heart). It uses an inner-heart biopsy and tailored treatment based on the likely cause to improve diagnosis and care, especially for people with different heart rhythm or non-rhythm symptoms.
Milan, MilanoAges 18 years+ - NCT05537753Recruiting
PFO closure device test after recent unexplained stroke
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
Little Rock, ArkansasAges 18–60 - NCT05828862Recruiting
Checks blood-pressure drops during major upper stomach surgery
This trial studies what happens when blood pressure drops during planned (elective) major upper gastrointestinal surgery and looks at related blood chemistry. Your care team may collect samples during the operation to understand why this happens and how to improve outcomes.
TaipeiAges 20–80 - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT06410274Recruiting
MRI study of brain damage after bleeding stroke
This study looks at small areas of damage (called ischaemic lesions) seen on MRI after a bleeding stroke. It aims to understand how common they are and what they mean for recovery. Participants will have an MRI scan within a few days of their stroke.
LeicesterAges 18–120 - NCT07751783Recruiting
Exercise program for cancer survivors
This trial helps people who have finished cancer treatment start a supervised exercise routine to improve their health. It tests whether a structured program with professional guidance is safe and helpful.
Kaohsiung, TaiwanAges 18–80 - NCT07757282Recruiting
Blood lipid (fat) levels in atrial fibrillation
This study looks at fats (lipids) in the blood of people with atrial fibrillation (an irregular heartbeat) compared to people with other heart conditions but no atrial fibrillation. The goal is to find patterns that may help understand the condition better and improve diagnosis or treatment.
Xi'an, ShaanxiAges 18 years+ - NCT07754110Recruiting
A therapy for balance and coordination after stroke
This study tests a therapy called HABIT-ILE to see if it helps improve balance and coordination in people who have had a stroke. If you have had a stroke affecting one side of your body, this might help you move better.
Mansehra, KpkAges 40–60 - NCT07752303Enrolling by invitation
Comparing two anaesthesia methods for weak hearts
This study compares two types of anaesthesia for people with a weakened heart (ejection fraction between 35-40%) who need planned lower-limb surgery. It looks at how each method affects blood pressure and heart function during and after the procedure.
SargodhaAges 18–70 - NCT07754188Recruiting
Comparing two treatments for unruptured brain aneurysms
This study compares two ways to treat a type of brain aneurysm (a weak spot in a blood vessel) that has not burst. It looks at early problems after using a flow diverter or stent-assisted coiling, to see which might be safer or more effective.
Guangzhou, GuangdongAges 18–75 - NCT07752732Recruiting
Heart scans for amyloidosis in people with severe aortic valve stenosis
This study looks at how often cardiac amyloidosis occurs in people with severe aortic valve stenosis. It uses different heart scans to find out more. If you have both conditions, this research may help doctors understand your situation better.
TübingenAges 18 years+ - NCT07753473Recruiting
Brain stimulation for young adults with depressive symptoms
This study uses a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) to see if it can improve how the brain and heart work together in people aged 18 to 30 who have mild depressive symptoms. The goal is to understand if this treatment could help with mood regulation.
Xi'an, ShaanxiAges 18–30 - NCT07750184Recruiting
Kinesio taping for immediate relief in thoracic outlet syndrome
This trial tests whether a special tape, called Kinesio tape, can quickly reduce symptoms of thoracic outlet syndrome, a condition where nerves or blood vessels are squeezed in the space between the collarbone and first rib. It may help with pain, numbness, or weakness in the arm and hand.
Merkez, SivasAges 20–45 - NCT07756775Recruiting
Comparing two imaging tests for stroke diagnosis
This study compares two imaging methods, magnetic resonance imaging (MRI) without contrast dye and a carotid ultrasound (Doppler), to see which one is better at finding blocked arteries in the neck that can cause strokes. The results may help doctors choose the best test for people who have had a stroke or a mini-stroke.
Sohag, Sohag GovernorateAges 18 years+ - NCT07754747Recruiting
Balance training after stroke
This trial compares two types of balance exercises to see which one better improves balance, posture, and reduces the risk of falling in people who had a stroke at least 6 months ago.
RawalpindiAges 40–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.