Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06774794Recruiting
Precision medicine for heart transplant patients
This trial uses precise, personalized approaches to manage heart transplant recipients. It involves taking a small heart muscle sample (a biopsy) to monitor for rejection or routine checks.
BolognaAges 18 years+ - NCT07446088Recruiting
Home electric stimulation for better blood flow
This trial tests a home-use device that uses mild electric stimulation to improve blood circulation. It may help if you are looking for a non-drug way to boost circulation.
WŏnjuAges 19–65 - NCT06985394Recruiting
Blood vessel health and stress in emergency responders
This study looks at how shift work affects blood vessel function and oxidative stress in emergency medical responders. It may help understand why first responders have higher risk for heart problems.
Newark, DelawareAges 20–40 - NCT06984406Recruiting
Beet product for kidney protection during heart procedure
This trial tests a beet-derived food product (a natural source of nitrate) to see if it can help prevent kidney damage caused by the contrast dye used during a heart procedure called PCI. It is designed for people who already have a higher risk of this kidney problem.
MoscowAges 18 years+ - NCT07443072Recruiting
Heart rate and brain waves to predict recovery after brain surgery
This study monitors your heart rate and brain waves during and after brain surgery to see if they can help doctors predict how well you will recover. It aims to improve care for future patients.
MilanAges 18 years+ - NCT06455566Enrolling by invitation
Placing a leadless pacemaker through the right neck vein
This study is testing a new way to place a small, wire-free pacemaker through a vein in the neck. It may be an option if you need a pacemaker and your doctor says a leadless one is suitable for you.
AngersAges 18 years+ - NCT06598930Recruiting
Nurse-led follow-up after mild lung blood clot
This study compares two ways of following up after a non-severe pulmonary embolism: standard medical care alone versus intensive monitoring that includes an advanced practice nurse. The goal is to see if the nurse-led follow-up improves your recovery and quality of life.
DijonAges 18 years+ - NCT05994274Recruiting
Heart transplant, cholesterol, and organ rejection study
This study looks at whether changes in blood fats (cholesterol and triglycerides) after a heart transplant are linked to the risk of organ rejection. It may help doctors better monitor and protect your new heart.
WuhanAges 18 years+ - NCT07400991Recruiting
Restrictive vs liberal fluids for hospitalized heart failure
This trial studies whether drinking less fluid (restrictive) vs. the usual amount (liberal) helps people hospitalized with heart failure. It aims to find out which approach leads to better recovery and fewer symptoms.
HerningAges 18 years+ - NCT07449377Recruiting
Can a liver scan help diagnose heart failure in the ER?
This study tests whether a quick, non-invasive liver scan (Fibroscan) can help diagnose heart failure in people who come to the emergency department with sudden shortness of breath.
ParisAges 18 years+ - NCT05707637Recruiting
A heart procedure registry comparing two ablation approaches
This study keeps a detailed record of people with certain abnormal heart rhythm beats who are treated with a catheter ablation. It compares outcomes after a standard “unipolar” approach using radio-frequency ablation and then a further step (“bipolar” radio-frequency ablation) when appropriate.
WarsawAges 18 years+ - NCT07147114RecruitingPhase 4
Combined macitentan and dapagliflozin for heart failure with lung high blood pressure
This trial tests whether adding two medications—macitentan and dapagliflozin—together is safe and effective for people with heart failure and a certain type of high blood pressure in the lungs. It might help improve your symptoms and daily function.
BusanAges 19 years+ - NCT06896708Recruiting
Intensive cholesterol treatment for heart plaque in younger adults
This trial tests whether higher doses of cholesterol-lowering medication (statins) can slow down plaque buildup in the heart arteries of younger and middle-aged adults with stable chest pain. It may help prevent heart attacks and the need for procedures like stents.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT07419048Recruiting
AI vs. human for hydration check
This study uses an ultrasound method to check your hydration status, comparing artificial intelligence (computer analysis) with a human expert. It aims to see if AI can accurately assess how hydrated you are.
BaselAges 18 years+ - NCT06586008Recruiting
Heart failure ultrasound and recovery study
This trial uses a special ultrasound scoring system to see how well people with a certain type of heart failure (weak heart pumping) are doing. It looks at whether this score can predict how their recovery goes.
Semarang, Central of JavaAges 18–70 - NCT06432387Recruiting
Blood clotting changes during complex aneurysm repair
This study looks at how blood clotting factors change during a complex aneurysm repair. It may help doctors better understand and manage bleeding risks.
Larissa, ThessalyAges 18 years+ - NCT06898515RecruitingPhase 3
Fluid removal study for acute heart failure patients
This trial tests a device designed to safely remove extra fluid from patients hospitalized with worsening heart failure. It may help those who are not responding well to standard water pills (diuretics).
Irvine, CaliforniaAges 22 years+ - NCT07410988RecruitingPhase 4
Starch vs. crystalloid fluid for heart surgery patients
This trial compares two types of IV fluids (a starch solution vs. a balanced salt solution) to see which one better protects kidneys after heart surgery. It is for adults having planned heart surgery who do not have severe kidney problems.
DaejeonAges 19 years+ - NCT07202000RecruitingPhase 2
Exercise and a drug to reduce inflammation for heart failure with preserved ejection fraction
This trial tests whether combining exercise with a medication that blocks a protein called activin can reduce inflammation, improve heart function, and help with thinking in people with heart failure with preserved ejection fraction (HFpEF).
Boston, MassachusettsAges 40 years+ - NCT07399392Recruiting
Radial vs. femoral secondary access during TAVI
This trial compares two ways to get a second access site during a TAVI procedure: using the wrist artery (radial) or the groin artery (femoral). The goal is to see which approach is safer and works better for patients like you.
Freiburg im BreisgauAges 18 years+ - NCT07399093Recruiting
Ultrasound test before brain surgery anesthesia
This trial uses ultrasound to measure blood flow and fluid levels in the body before brain surgery. It aims to help doctors manage fluids better during and after anesthesia.
CairoAges 18–40 - NCT07150260Recruiting
Brain oxygen and artery pressure study during awake carotid surgery
This study looks at how blood pressure in the carotid artery relates to oxygen levels in the brain during awake carotid surgery. It may help doctors better understand how to protect your brain during the procedure.
IzmirAges 18 years+ - NCT06583876Recruiting
A new device for leaky mitral valves without open-heart surgery
This trial tests a new device for people whose mitral valve leaks badly (grade 3+ or 4+) and who are not candidates for surgery. The device aims to fix the leak through a less invasive approach, and the study checks if it's safe and works well in daily life.
BudapestAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.