Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07878299Recruiting
Comparing body fat patterns in lipedema and obesity
This study compares body composition between women with lipedema (a condition causing abnormal fat buildup in the legs) and women with similar weight who do not have lipedema. The goal is to better understand how these conditions differ, which may improve diagnosis and treatment.
Istanbul, UskudarAges 18–65 - NCT06973564RecruitingPhase 1/Phase 2
Study of an experimental drug for advanced solid tumors with KRAS changes
This trial tests an experimental pill, JAB-23E73, for people with advanced solid tumors that have a specific genetic change called KRAS. The drug may block the effects of this altered gene, potentially slowing or stopping tumor growth.
Rochester, MinnesotaAges 18 years+ - NCT06465069RecruitingPhase 1
Study of an experimental drug for advanced bladder and other cancers
This trial tests a new drug called LY4052031 for people with advanced or metastatic cancers, especially bladder cancer. The drug aims to slow or stop tumor growth. Doctors will check if it is safe and how well it works.
Duarte, CaliforniaAges 18 years+ - NCT07238556Recruiting
Digital exercise program for cardiovascular risk
This study tests a new digital tool that helps clinicians prescribe personalized exercise plans to patients with cardiovascular risk factors like high blood pressure, diabetes, or obesity. Participation involves using the tool and following an exercise plan for a few months to see if it improves health.
Farmington, ConnecticutAges 18–64 - NCT07877090Recruiting
Brain activity during anesthesia in people with obesity
This study looks at how anesthesia affects brain waves in people with obesity compared to people with normal weight. It may help doctors understand if anesthesia needs to be adjusted for people with obesity.
Düzce, DüzceAges 18 years+ - NCT07676188Recruiting
Help with diabetes care and daily needs
This study offers support from trained peers who have diabetes themselves. The goal is to help you manage your diabetes and find resources for financial or everyday needs, such as food, housing, or transportation.
Ann Arbor, MichiganAges 18 years+ - NCT06220773RecruitingPhase 3
combination treatment for type 2 diabetes and high blood pressure
This study tests two new combination medicines for people who have both type 2 diabetes and high blood pressure. It looks at how well they work and how safe they are. Participants stop their current diabetes and blood pressure drugs during the trial, except for the diabetes drug metformin.
Jakarta, DKI JakartaAges 19 years+ - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT07816666RecruitingPhase 3
Maintenance treatment for relapsed ovarian cancer
This trial tests a new drug called torvutatug samrotecan, given alone or with bevacizumab, as maintenance therapy after chemotherapy for ovarian cancer that has come back. It aims to see if this treatment can help keep the cancer from growing longer.
Anchorage, AlaskaAges 18 years+ - NCT07877727Recruiting
Rare blood disease network for better care
This study creates a national network to collect health information and samples from people with certain rare blood diseases. The goal is to improve treatment and understand these conditions better.
AvellinoAges 4 weeks–65 years - NCT07878325Recruiting
Specialized heart and diabetes clinic for people with type 2 diabetes
This trial tests a specialized clinic that combines diabetes and heart care for people with type 2 diabetes who also have heart or blood vessel problems. The clinic will also check for unrecognized heart failure to improve overall health.
SvendborgAges 18 years+ - NCT07852338RecruitingPhase 3
Placental graft for diabetic foot ulcers
This trial tests a treatment made from placental tissue, called Bioxheal, which is placed on a diabetic foot ulcer to help it heal. It compares this treatment to standard care alone.
Boardman, OhioAges 18 years+ - NCT00344331Recruiting
Testing blood and MRI markers for Niemann-Pick type C
This study measures biochemical (blood/biologic) markers and may use clinical evaluation and MRI to better understand Niemann-Pick disease type C. It could help improve how the condition is tracked and understood over time.
Bethesda, MarylandAges 1 day–120 years - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Mesa, ArizonaAges 18 years+ - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT05229341Recruiting
Testing DNA “methylation” to evaluate thyroid nodule samples
This study looks at patient tissue from needle biopsies to see if DNA “methylation” patterns can help diagnose and guide treatment for thyroid nodules. You might benefit by helping improve how these nodules are evaluated, using information from your biopsy sample and medical data.
Duarte, CaliforniaAges 18 years+ - NCT07871071Recruiting
Brain-computer interface communication device for ALS
This trial tests a brain-computer interface (BCI) device that lets people with ALS communicate using brain signals, without needing to move. It may help those who have difficulty speaking or using eye-gaze devices.
Santa Barbara, CaliforniaAges 18 years+ - NCT05147701RecruitingPhase 1
Testing stem cell treatment for NAION safety
This Phase 1 study tests whether lab-made stem cells taken from donated umbilical cord are safe for people with NAION. It mainly looks for side effects and safety rather than proving the treatment works.
Naples, FloridaAges Any age - NCT07298603Enrolling by invitation
Nutrition plan for women with PCOS
This study tests whether a specific nutrition plan can help women with PCOS improve their health. You would follow a guided diet and have check-ins to see how it affects your symptoms and well-being.
Samsun, AtakumAges 20–45 - NCT06487481RecruitingPhase 1
Radiation before surgery for recurrent adrenal cancer
This trial tests whether giving radiation before surgery helps people with adrenal cancer that has come back after previous treatment. It aims to see if this approach can improve outcomes for patients who can have surgery at the NIH.
Bethesda, MarylandAges 18–120 - NCT07855133RecruitingPhase 1
Switching to a new treatment for weight or diabetes
This study tests a new medicine called zenagamtide for adults with overweight or obesity, with or without type 2 diabetes, who are currently taking semaglutide. The goal is to see how well people tolerate switching from semaglutide to the new treatment.
Glendale, CaliforniaAges 18 years+ - NCT07741968Recruiting
Online program to ease fear of cancer returning
This study tests an online program designed to help women with advanced or certain types of breast or gynecologic cancer manage their fear of the disease progressing or returning. The program aims to reduce anxiety and improve quality of life.
Arcadia, CaliforniaAges 18 years+ - NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes
This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.
Birmingham, AlabamaAges 18–45 - NCT06190717Recruiting
Ultrasound implant to help dialysis fistula mature
This study tests whether a special ultrasound implant (EchoMark) helps a new dialysis fistula mature properly. It involves people with advanced kidney disease who are starting or already on dialysis and are having a fistula created in the upper arm.
Dothan, AlabamaAges 18–84
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.