Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT05516576Recruiting
Weight-loss procedure plus diabetes care for type 2 diabetes
This trial studies whether an endoscopic (camera-guided) stomach tightening/suturing procedure plus standard diabetes care can improve health in people with type 2 diabetes and mild-to-moderate obesity. It compares this procedure to standard care alone to see which approach works better and is safe.
La TroncheAges 18–65 - NCT05601141Recruiting
Study of pituitary disorders in Modena-area clinic patients
This study looks at people with pituitary gland disorders who receive care at a specific endocrinology clinic in Modena. It may help doctors better understand these conditions in the local patient population.
Modena, ModenaAges 18 years+ - NCT06178887Recruiting
Cardiac MRI for heart and blood vessel issues in Turner syndrome
This study uses cardiac MRI to look for heart and blood vessel differences in adults with Turner syndrome. It may help find problems early so you can get the right care.
ModenaAges 18 years+ - NCT07297290RecruitingPhase 3
Testing Metformin for Weight Loss in Obesity
This trial tests whether metformin, a common diabetes medicine, can help people with obesity lose weight. It is for people who do not have diabetes and have not used weight loss treatments in the past year.
Enugu, Enugu StateAges 20–59 - NCT07297342Recruiting
Comparing ways to use the 'Get Ready' app for weight loss surgery
This study compares two ways of using a smartphone app called 'Get Ready' to help people follow their pre-surgery plan before weight loss surgery. It aims to see which approach helps patients stay on track better.
GeelAges Any age - NCT07300163Recruiting
FeetSee: Thermal images for diabetes foot health
This study collects thermal (heat) images of the feet of people with diabetes who have had a healed foot ulcer. The goal is to see if these images can help prevent future foot problems.
VilniusAges 18 years+ - NCT07301749Recruiting
Study of VCFix device for spine fractures
This trial tests a new device called VCFix to treat a single broken vertebra in the mid-to-lower back. It aims to see if the device is safe and effective for relieving pain and restoring spine function.
ChambéryAges 21–85 - NCT07298135Recruiting
Prebiotic soda and blood sugar in prediabetes
This study is testing whether a prebiotic soda (a type of soda with extra fiber) can help improve blood sugar control in adults with prediabetes. You would replace 2-3 of your regular sodas each day with the study soda for a set period of time.
Los Angeles, CaliforniaAges 30–70 - NCT07305818RecruitingPhase 1
Testing a new drug for Graves' disease
This study tests a new medication called MER511 for adults with Graves' disease. The goal is to see if it is safe and how it works when taken once or multiple times.
Torrance, CaliforniaAges 18–65 - NCT07303296RecruitingPhase 2
Gene therapy study for vision loss from LHON
This trial tests a gene therapy called GS010 given as an injection into the eye for people with vision loss from LHON. It aims to see if it can help improve vision in both eyes.
ParisAges 15 years+ - NCT07298343RecruitingPhase 2
Testing ZED1227 for non-responsive celiac disease
This trial tests a new medicine, ZED1227, for people with celiac disease who still have symptoms despite eating gluten-free. The goal is to see if it helps reduce those symptoms.
MainzAges 18–80 - NCT07300150RecruitingPhase 1
PT0511 for KRAS-mutated or amplified advanced solid tumors
This trial tests a new drug called PT0511 that targets a specific gene change (KRAS) found in some advanced solid tumors. It's for people whose cancer has not responded well to other treatments and who are looking for a new option.
Boston, MassachusettsAges 18 years+ - NCT07304128RecruitingPhase 1
PLB-002 for advanced solid tumors study
This trial tests a new drug called PLB-002 for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and effective, especially for cancers that show a specific marker called CLDN6.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06541834Recruiting
Predicting diabetes eye nerve problems with retina scans
This study uses artificial intelligence to analyze retinal images and predict the risk of nerve-related problems caused by diabetes. It may help identify those at risk before symptoms appear.
MilanAges 45 years+ - NCT07302672Recruiting
WeChat support for thyroid cancer patients after heat ablation
This study tests whether extra support through the WeChat app can help people with small papillary thyroid cancers recover better after a heat-based tumor treatment called thermal ablation. You'd use your smartphone to get check-ins and advice from the care team.
BeijingAges 16–60 - NCT07297745Recruiting
Guiding curative treatment for primary aldosteronism with a hybrid steroid
This trial tests whether a special type of steroid medicine can help guide treatment for primary aldosteronism, a condition that causes high blood pressure. If the tests show the problem is in one adrenal gland, you might be able to have surgery to cure it.
Singapore, SingaporeAges 21 years+ - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07302321Recruiting
Needs of ALS patients with C9orf72 mutation and their caregivers
This study asks people with ALS who have a specific genetic change (C9orf72) and their caregivers to fill out an online survey. It aims to better understand their needs so that support can be improved.
Milan, LombardyAges 18 years+ - NCT07298486Enrolling by invitation
Robotic glove to help with grip and hand function in ALS
This trial tests whether a robotic glove can improve quality of life, grip strength, and fine motor control in people with ALS. If you have trouble with hand strength or dexterity, this device may help you regain some function.
Davie, FloridaAges 18–99 - NCT07303387RecruitingPhase 2
Valemetostat for solid tumors with SWI/SNF gene changes
This trial tests a new drug, valemetostat, for solid tumors that have specific genetic changes (like loss of SMARCB1, SMARCA4, or ARID1A). It is for people whose cancer has continued to grow despite other treatments. The study will see if valemetostat can help shrink or slow tumors.
Villejuif, Val de MarneAges 18 years+ - NCT07303803RecruitingPhase 2
Testing Chiglitazar for fatty liver with diabetes
This trial tests a new oral medication, Chiglitazar, for people who have both type 2 diabetes and a fatty liver condition called MASH (fatty liver with inflammation and scarring). It aims to see if the drug can help improve liver health and diabetes control.
Beijing, Beijing MunicipalityAges 18–75 - NCT07304778Recruiting
Mobile app study for insulin dosing in type 1 diabetes
This trial tests a smartphone app that helps people with type 1 diabetes predict their blood sugar and decide how much insulin to take. It may be a good fit if you already use multiple daily insulin injections and a continuous glucose monitor.
Madrid, MadridAges 18–65 - NCT07303894RecruitingPhase 2
Isoquercetin for ovarian cancer patients
This trial tests if a plant-based supplement called isoquercetin can help people with ovarian cancer when given alongside their first chemotherapy. It aims to see if it improves treatment results.
Boston, MassachusettsAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.