Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT07298564Recruiting
Magnesium and levocarnitine for PCOS symptoms
This trial tests whether taking magnesium and levocarnitine (a natural substance that helps cells make energy) can improve metabolism and reduce symptoms like irregular periods or weight gain in women with polycystic ovary syndrome (PCOS). If you have PCOS, you may be able to join.
Tehran, Tehran ProvinceAges 19–65 - NCT07300293Recruiting
Metformin and lactic acidosis in intensive care
This study looks at patients in intensive care who had lactic acidosis, to see if taking metformin before admission played a role. It may help understand how metformin affects recovery.
StrasbourgAges 18 years+ - NCT07303140Recruiting
Liver stiffness in young people with glycogen storage disease type III
This study looks at liver stiffness (a sign of scarring, called fibrosis) in children and young adults with type III glycogen storage disease. Researchers want to see how common liver fibrosis is in this group and how it changes over time, using a non-invasive ultrasound-like test called elastography.
StrasbourgAges 1 month–21 years - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07299942Recruiting
Beta-glucan supplement for weight loss in women
This trial tests whether taking a beta-glucan supplement (a type of fiber) during a calorie- and carb-restricted diet helps with losing body weight and fat, controlling appetite, and managing hunger hormones. It is for healthy women who are overweight or obese and not following a special diet.
GlasgowAges 18–60 - NCT07298954Recruiting
Comparing adrenal vein sampling methods for primary aldosteronism
This trial compares different ways of doing adrenal vein sampling (a test to find which adrenal gland is causing high blood pressure). It aims to see if combining methods works better than using just one for people with primary aldosteronism.
ChongqingAges 18–70 - NCT07300332Recruiting
Exercise training and vitamin D study
This trial tests whether exercise affects how your body uses vitamin D. It might help if you have a higher BMI and do not take certain medications or supplements.
Trikala, KaryesAges 35–50 - NCT07305168Recruiting
Breathing after tonsil surgery in children with sleep apnea
This study looks at breathing problems that can happen after tonsil or adenoid surgery in children who have sleep apnea. Researchers want to learn more so they can make surgery safer for kids.
Edegem, AntwerpAges 1–18 - NCT07304193Enrolling by invitation
Study of sex chromosome disorders in fetuses
This study looks at the genetics of fetuses with sex chromosome disorders. It compares them to fetuses without these conditions to understand more about how these disorders affect development.
AarhusAges 3 months–5 months - NCT07301216Recruiting
Copper in urine after stopping Wilson disease therapy
This study is looking at what happens to copper levels in the urine when people with Wilson disease briefly stop their medicine. It may help doctors understand how well your body controls copper without treatment.
New Haven, ConnecticutAges 18 years+ - NCT07298057RecruitingEarly Phase 1
Dental implant study for people with diabetes
This study tests if adding an antibiotic (Arestin) to standard gum cleaning can improve gum health and blood sugar control in people with type 2 diabetes.
Cleveland, OhioAges 18 years+ - NCT07298408RecruitingPhase 1/Phase 2
CBD for Diabetic Nerve Pain: A Pilot Study
This trial tests whether a daily dose of CBD (a cannabis compound) can help reduce nerve pain from type 2 diabetes. It's a small, early study to see if it's safe and effective.
Tallahassee, FloridaAges 40–70 - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07301814Recruiting
PET imaging for CLDN18.2 in cancer patients
This study uses a special PET scan to look for a protein called CLDN18.2 on cancer cells. It may help doctors better understand certain cancers like stomach, pancreas, bile duct, or esophageal cancer and guide treatment decisions.
Wuhan, HubeiAges 18 years+ - NCT07304778Recruiting
Mobile app study for insulin dosing in type 1 diabetes
This trial tests a smartphone app that helps people with type 1 diabetes predict their blood sugar and decide how much insulin to take. It may be a good fit if you already use multiple daily insulin injections and a continuous glucose monitor.
Madrid, MadridAges 18–65 - NCT07303387RecruitingPhase 2
Valemetostat for solid tumors with SWI/SNF gene changes
This trial tests a new drug, valemetostat, for solid tumors that have specific genetic changes (like loss of SMARCB1, SMARCA4, or ARID1A). It is for people whose cancer has continued to grow despite other treatments. The study will see if valemetostat can help shrink or slow tumors.
Villejuif, Val de MarneAges 18 years+ - NCT06877975Recruiting
Testing a new device for glucose and ketone monitoring in healthy adults
This trial tests a new device that tracks blood sugar and ketone levels continuously. It is for healthy people aged 18–45 to see how well the device works.
Waterloo, OntarioAges 18–45 - NCT03634930Recruiting
Study of how early pregnancy choices affect your baby
This trial looks at how “perinatal programming” (early-life influences starting around pregnancy and the first month) may affect babies. It enrolls healthy, full-term births and compares families who can follow an all-breastfeeding or all-formula plan.
Graz, StyriaAges 18–50 - NCT05977348Recruiting
Preschool nutrition lessons to help prevent future obesity
This trial tests a program to improve food knowledge and healthy eating habits in preschool children. It may help families by teaching practical ways to choose and handle foods earlier to reduce later obesity risk.
University Park, PennsylvaniaAges 3–6 - NCT06878534Recruiting
Thyroid cancer genetic study for patients with follicular origin
This study looks at the genes and mutations in thyroid cancers that start in follicular cells. It aims to understand how these changes relate to how aggressive the cancer is.
NaplesAges 18 years+ - NCT06488313RecruitingPhase 2
Study of ARCT-810 for people with OTC deficiency
This trial tests an experimental medicine called ARCT-810 for people with Ornithine Transcarbamylase (OTC) deficiency, a condition that affects the liver's ability to remove ammonia from the body. The study aims to see if ARCT-810 can help lower ammonia levels safely.
Chevy Chase, MarylandAges 12 years+ - NCT06849609RecruitingEarly Phase 1
Gene therapy VGN-R13 for ALS safety and tolerability
This study tests a new gene therapy called VGN-R13 for people with ALS. It aims to see if the treatment is safe and tolerable, and if it can slow down the disease. You may be able to join if your ALS symptoms started recently and your lung function is still fairly good.
Wuhan, HubeiAges 18 years+ - NCT06875193RecruitingPhase 4
Comparing dapagliflozin vs pioglitazone for type 2 diabetes
This study is testing two different diabetes pills—dapagliflozin or pioglitazone—in people with type 2 diabetes. The goal is to see which one works better when added to your current metformin and DPP-4 inhibitor. You may qualify if your blood sugar is not well controlled with your current medications.
SeoulAges 19 years+ - NCT06867952Recruiting
Vitamin K2 for bone loss with a specific gene change
This study tests whether taking vitamin K2 can help people with low bone density (osteopenia or osteoporosis) who have a specific change in the VDR gene. If you have this gene change, vitamin K2 may work better for you than standard supplements.
NovosibirskAges 40–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.