Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06929650Recruiting
Radiofrequency ablation for low-risk thyroid cancer
This trial tests a procedure called radiofrequency ablation to treat small, low-risk thyroid cancer. If you have a small nodule (2 cm or less) that is confirmed as cancer or suspicious for cancer (Bethesda 5/6), this treatment may be an option instead of surgery.
Toronto, OntarioAges 18–100 - NCT06927375RecruitingPhase 4
Combination drug therapy for thyroid eye disease
This study tests a combination of two drugs, tocilizumab and flupentixol-melitracen, in people with active, moderate-to-severe thyroid-associated eye disease (TED). It aims to see if this combination can reduce eye bulging, double vision, and anxiety symptoms.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06928844Recruiting
Low dose progesterone injection for ovulation
This trial tests whether a low dose of progesterone (a hormone) can help trigger ovulation in women who have trouble getting pregnant. It may offer a new option for women with infertility.
CairoAges 20–35 - NCT04192422Recruiting
DiGEST newborn study follow-up for enrolled mother-baby pairs
This study looks at newborns and their mothers who were already enrolled in the DiGEST trial and agreed to take part. If you’re part of that earlier DiGEST trial, this may be a next step for your care team to collect more information.
Cambridge, CambridgeAges Any age - NCT05374278RecruitingPhase 1/Phase 2
PET scan test for a dementia brain tracer
This early-phase study tests a new PET scan tracer that targets a brain chemical transport system involved in dementia. It aims to see if the tracer can safely and clearly show brain changes, which could help future dementia diagnosis or tracking.
San Francisco, CaliforniaAges 40–75 - NCT06931730Recruiting
Exercise and cognitive training for overweight individuals
This trial tests a program that combines exercise, cognitive training, and social activities to help people with overweight or obesity manage their energy balance. It may improve overall health and weight control.
Rome, ItalyAges 6–11 - NCT06931275Recruiting
Reducing technology gaps in type 1 diabetes care
This trial tests if sending reminders to doctors can help more Black and Hispanic people with type 1 diabetes get access to helpful diabetes technology. It aims to reduce unfair differences in who gets to use these tools.
Boston, MassachusettsAges 2–95 - NCT06932445Recruiting
Malnutrition's effect on liver and spleen stiffness in kids
This study measures how malnutrition affects liver and spleen stiffness (tissue hardness) in children using a non-invasive ultrasound test called elastography. It compares these measurements between malnourished children and healthy children to understand potential organ changes.
Konya, KonyaAges 1 month–18 years - NCT06932042Recruiting
Protein-controlled diet for kidney disease management
This trial tests a low-protein diet (called PLADO) to help manage chronic kidney disease (CKD) stages 3–5. It aims to slow kidney decline and improve nutrition. You may join if your kidney function is stable and your blood sugar and blood pressure are under control.
BeirutAges 18 years+ - NCT04370899Recruiting
Early checkup for inherited high cholesterol in children
This study looks at children who may have inherited high cholesterol, especially when one parent is affected. It may help doctors detect the condition earlier and understand how it runs in families.
Reus, TarragonaAges 2–18 - NCT06932705RecruitingPhase 1
Comparing PA-111 and PA-111A in healthy volunteers
This trial tests how two study drugs, PA-111 and PA-111A, are processed by the body and how safe they are. Healthy volunteers are needed to compare the two drugs.
SeoulAges 19 years+ - NCT06933108Recruiting
Predicting Nerve Damage with Simple Function Tests
This study looks at whether simple function tests can predict nerve damage in people with advanced kidney disease or diabetes. It aims to find early signs of nerve problems before they become serious.
Le MansAges 60–80 - NCT06842524RecruitingPhase 2
Dihydroartemisinin for PCOS: A Phase 2 Trial
This trial tests if dihydroartemisinin (a medicine derived from a plant) can help women with PCOS. It may improve hormone balance and menstrual cycles.
Xiamen, FujianAges 18–40 - NCT06843304Recruiting
Diabetes kidney disease prevention and control study
This trial tests a new system to manage diabetic kidney disease across all stages. It is for people with type 2 diabetes who either have no kidney damage or have kidney damage confirmed by a biopsy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05038683Recruiting
Child weight program study: new treatment vs usual care
This trial tests a structured obesity treatment program for children compared with the usual (conventional) approach. It may help your child get support to improve healthy weight habits.
Ballerup Municipality, BallerupAges 6–11 - NCT06875167Recruiting
Automated insulin therapy for kids 2-6 with type 1 diabetes
This study tests a semi-automated insulin pump system in very young children (ages 2–6) with type 1 diabetes. It aims to see if the device improves quality of life and blood sugar control.
Nice, FranceAges 2–6 - NCT06936137RecruitingPhase 3
Probiotics for weight gain from antipsychotic medication
This trial tests if taking a probiotic supplement can help prevent or reduce weight gain caused by certain antipsychotic medications. It is for people with schizophrenia who have gained significant weight after starting these medications.
Cairo, AbbassiaAges 18–45 - NCT07202598RecruitingPhase 2
Testing emapalumab for gut inflammation in APECED
This trial tests a drug called emapalumab to treat chronic gut inflammation (enteritis) in people with APECED, a rare immune disorder. It aims to see if the drug can help when other treatments haven't worked.
Bethesda, MarylandAges 2–75 - NCT07194733Recruiting
Food as medicine for veterans with kidney disease
This trial tests whether providing healthy food can improve the health of veterans with moderate to severe chronic kidney disease (stages 3b and 4) who are not getting enough nutritious food. If you are a VA patient in the Food Bank of the Rockies area, this study may help you manage your kidney disease.
Aurora, ColoradoAges 18 years+ - NCT07199829Recruiting
Vitamin D and K for military healthcare workers
This study tests whether taking vitamin D3 and K2 supplements can improve health in military healthcare workers who have low vitamin D levels. If you qualify, you will stop any current vitamin D or K supplements and take the study supplement for 4.5 months.
Tacoma, WashingtonAges 18–69 - NCT07199946RecruitingPhase 1/Phase 2
Verapamil to protect insulin production in children with new type 1 diabetes
This study tests if verapamil (a common blood pressure medication) can help children newly diagnosed with type 1 diabetes keep making their own insulin for longer. It aims to preserve the body's own insulin-producing cells, which may reduce the amount of insulin injections needed.
JönköpingAges 4–9 - NCT07197775Enrolling by invitation
Endogenex PULSE Registry: Tracking long-term outcomes
This registry collects information from people with type 2 diabetes who have already been treated with the Endogenex System. It helps researchers learn how the treatment works over time.
Quincy, MassachusettsAges 18 years+ - NCT07195175RecruitingPhase 1
Safety study of MAR002 in healthy men
This early-phase trial tests a new investigational drug called MAR002 in healthy men. The goal is to see how safe the drug is and how the body handles it before moving to larger studies.
Tempe, ArizonaAges 18–40 - NCT07197944RecruitingPhase 3
Glepaglutide for short bowel syndrome
This trial tests a new medication called glepaglutide to see if it can help people with short bowel syndrome (SBS) who need IV nutrition or fluids at least 3 days a week. The goal is to reduce or even stop the need for these IV treatments.
Chicago, IllinoisAges 18–90
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.