Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06976177RecruitingPhase 2
MT1013 for secondary hyperparathyroidism in dialysis patients
This study tests a new injectable medicine called MT1013 for people with secondary hyperparathyroidism who are on regular kidney dialysis. It aims to see if MT1013 can help control high parathyroid hormone levels safely.
Hangzhou, ZhejiangAges 18 years+ - NCT06278935Recruiting
Adapting lifestyle offloading for diabetic foot ulcers
This trial tests a lifestyle-based offloading program for people with diabetic foot ulcers (DFUs). It aims to see if a tailored approach can help healing and prevent complications, using telehealth for support.
Los Angeles, CaliforniaAges 21 years+ - NCT06330350Recruiting
Talking about family planning for genetic skin conditions
This study interviews people with inherited skin conditions (genodermatoses) who want to have children, and the doctors who care for them. The goal is to learn how to better support family planning decisions, like counseling about genetics and pregnancy risks.
Maastricht, LimburgAges Any age - NCT06874010RecruitingPhase 1/Phase 2
Study of DT-216P2 in adults with Friedreich's ataxia
This trial tests an investigational drug called DT-216P2 in people with Friedreich's ataxia. It aims to find the right dose and see how safe and tolerable it is.
Sydney, New South WalesAges 18–65 - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT06979037Recruiting
Genetics of diabetic ulcers and personalized treatment
This study looks for genetic markers in people with type 2 diabetes and diabetic ulcers to help find better, personalized treatments. If you join, researchers will track your health to understand which treatments work best for your specific needs.
Hengyang, HunanAges 18 years+ - NCT06228001Recruiting
Movement monitoring in ALS patients
This study uses a wearable device to track movement patterns in people with ALS. It aims to better understand how the disease affects movement over time, which may help improve care.
LeuvenAges 18 years+ - NCT06851130Recruiting
Iron supplement study for women with low iron stores
This study tests how quickly a single oral iron dose increases ferritin levels in women who have low iron stores but are not anemic. It aims to find a quick way to assess iron absorption.
Zurich, Canton of ZurichAges 18–45 - NCT06083584Recruiting
Using RNA test to help diagnose ALS
This study is developing a new RNA test to improve the accuracy of diagnosing amyotrophic lateral sclerosis (ALS). It aims to see if this test can help doctors make a clearer and faster diagnosis.
BordeauxAges 18 years+ - NCT06687434Recruiting
Carb counting vs. simple meal-size estimation for type 1 diabetes
This study compares two ways of estimating meal size for people with type 1 diabetes who use automated insulin delivery systems. One method is detailed carb counting, the other is a simpler, qualitative estimate of meal size. The goal is to see which approach works better for managing blood sugar.
Petah TikvaAges 6–18 - NCT05915442RecruitingPhase 2
Adenosine blocker plus immunotherapy for limited prostate spread
This Phase 2 study tests a medicine that affects “adenosine” signaling along with an immune checkpoint inhibitor (immunotherapy) in men with hormone-sensitive prostate cancer that has spread in only a small, limited way. It aims to stop or slow that limited spread by helping the immune system work better.
New York, New YorkAges 18–99 - NCT06254859Recruiting
Nerve monitoring during thyroid surgery and voice outcomes
This study tests whether using nerve monitoring during thyroid surgery helps protect the nerves that control your voice. It includes adults having one side of their thyroid removed and tracks voice changes before and after surgery.
Fuzhou, FujianAges Any age - NCT06316752Recruiting
Natural history study of sialidosis type I
This study follows people with sialidosis type I over time to understand how the condition progresses. Participants will have regular exams, blood draws, brain scans, and eye tests.
Taipei, TaipeiAges 12–80 - NCT06665815Recruiting
Screening close family for type 1 diabetes risk
This study screens close family members of people with type 1 diabetes for early signs of the condition. A simple blood test looks for special markers (autoantibodies) that can show if the immune system is starting to attack the pancreas. Finding these markers early may help doctors prevent or delay the onset of diabetes.
Petah TikvaAges 2–45 - NCT06962202Recruiting
Modified Desmopressin PET/CT for Cushing's Syndrome
This trial tests a new way to use a medicine called desmopressin with a special type of imaging (PET/CT) to help find cortisol-producing tumors in people with Cushing's syndrome. It may help doctors better locate the problem without needing as much radiation.
ChandigarhAges 5–75 - NCT05235945Recruiting
Exercise program for people waiting for weight-loss surgery
This trial studies whether an exercise program can help people prepare for bariatric (weight-loss) surgery. It aims to see if exercise is safe and beneficial while you’re waiting for your surgery date.
LondonAges 18 years+ - NCT06577532RecruitingEarly Phase 1
KRAS mRNA vaccine for advanced solid tumors
This early-phase trial is testing a new mRNA vaccine (ABO2102) designed to target KRAS mutations in advanced solid tumors. It may be an option if your cancer has a KRAS mutation and standard treatments are no longer working.
ShanghaiAges 18 years+ - NCT06981676Recruiting
How early-life factors affect childhood obesity risk
This study looks at how a mother's weight before pregnancy and early prenatal care may influence the risk of obesity in their child. It aims to understand the origins of obesity starting from pregnancy.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07075393Recruiting
Kidney health in Wilson's disease
This study looks at how Wilson's disease affects the kidneys. It aims to describe kidney problems in people with Wilson's disease, which may help doctors better monitor and treat this condition.
ParisAges 7 years+ - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT06983054RecruitingPhase 4
Salt, kidneys, and ertugliflozin in type 2 diabetes
This study tests if changing how much salt you eat affects how the drug ertugliflozin works in people with type 2 diabetes. You would take either the drug or a placebo (a dummy pill) for a short time while following a low- or high-salt diet, to see how your kidneys and blood vessels respond.
Denver, ColoradoAges 18–85 - NCT07066657RecruitingPhase 1
Study of MRG007 for advanced solid tumors
This trial tests a new drug called MRG007 for people with advanced solid tumors that haven't responded to other treatments. The drug targets a protein called CDH17 on cancer cells; you need a tumor sample to check for it.
Los Angeles, CaliforniaAges 18 years+ - NCT07066098RecruitingPhase 3
New drug IBI343 for advanced pancreatic cancer with CLDN18.2 protein
This study tests a new drug called IBI343 compared to a placebo (inactive substance) for people with advanced pancreatic cancer that has a specific protein (CLDN18.2) and has not responded to earlier treatments. The goal is to see if IBI343 can help slow the cancer's growth.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07069335RecruitingPhase 1
Studying a new form of olaparib for BRCA-mutated ovarian cancer
This study tests a new form of a drug similar to olaparib (Lynparza) in people with BRCA-mutated ovarian cancer. It looks at how the drug works in the body and checks for safety, to see if the new formulation is as effective and safe as the current one.
Seoul, Songpa DistrictAges 19–74
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.