Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06686875Enrolling by invitation
Chronic belly pain after sleeve gastrectomy study
This study looks at long-term belly pain in people who had a sleeve gastrectomy 3 months to 5 years ago. It aims to understand the pain better to help future patients.
WarsawAges 18 years+ - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT06682481Recruiting
Pancreas-Liver Communication in Teens with Obesity
This study looks at how the pancreas and liver talk to each other in teens with obesity. It may help understand why some teens develop diabetes or fatty liver.
Geneva, Canton of GenevaAges 12–16 - NCT06686537RecruitingPhase 2
Study on metabolism and hormones in women
This study looks at how metabolism and hormones are connected in women. It tests a treatment to see if it can improve metabolic health related to the menstrual cycle.
Aurora, ColoradoAges 18–38 - NCT06683235Enrolling by invitation
Flaxseed for Type 2 Diabetes in Mexico
This trial tests if flaxseed can help control blood sugar in adults with type 2 diabetes. You may be able to join if you have diabetes that is not well-controlled and live in Oaxaca.
Oaxaca City, OaxacaAges 30–70 - NCT06687122Recruiting
Eggs, metabolism, and choline study
This trial studies how eating 3 eggs daily for 4 weeks affects your metabolism and choline levels. It may help if you have obesity and are looking for a simple dietary change to improve your health.
Québec, QuebecAges 30–65 - NCT06688461Recruiting
Exercise study to improve blood sugar in type 2 diabetes
This study tests whether high-intensity interval training can improve how your body uses insulin. It is for people with type 2 diabetes who are not on insulin and have had diabetes for 1 to 5 years.
SantiagoAges 45–75 - NCT06691100Recruiting
How one workout changes gut bugs in women
This study looks at how a single workout changes the bacteria in your gut. It compares women who are very fit with women who don't exercise much, and includes women with different body types.
Washington D.C., District of ColumbiaAges 21–40 - NCT06298916RecruitingPhase 1/Phase 2
Study of 64Cu-LNTH-1363S in Sarcoma or GI Cancer
This trial tests a new imaging agent, 64Cu-LNTH-1363S, to see if it can find certain sarcomas and gastrointestinal cancers. The goal is to help doctors better see where your cancer is and plan the best treatment. You may be eligible if you have a sarcoma or a GI cancer and are willing to have a tumor tissue sample taken.
Duarte, CaliforniaAges 15 years+ - NCT06690775RecruitingPhase 2
Study of a new drug for platinum-resistant ovarian cancer
This trial tests an investigational drug called TORL-1-23 for people with ovarian cancer that has stopped responding to platinum chemotherapy. It aims to see if the drug can help shrink or control the cancer.
Phoenix, ArizonaAges 18 years+ - NCT06689085RecruitingPhase 3
Testosterone replacement study for adolescent boys with low testosterone
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
Los Angeles, CaliforniaAges 12–17 - NCT06687733RecruitingPhase 1/Phase 2
Gene therapy for phenylketonuria
This trial tests a new gene therapy, NGGT002, which delivers a healthy gene to help people with phenylketonuria (PKU) manage their phenylalanine levels. It may reduce the need for strict diet control.
Bengbu, AnhuiAges 18–55 - NCT06688331RecruitingPhase 2
Treating early stage 1 type 1 diabetes in children with cell therapy and antibody
This trial tests a new combination treatment for children who have been diagnosed with stage 1 type 1 diabetes, meaning they have some markers but do not yet need insulin. The treatment uses special immune cells (Treg cells) and an antibody (anti-CD20) to try to preserve the body's ability to make insulin.
BialystokAges 3–18 - NCT05018221RecruitingPhase 3
Testing better treatment information for calciphylaxis ulcers
This Phase 3 study is for adults on regular dialysis who have a new calciphylaxis ulcer. It tests a better way to give and use treatment guidance so ulcers may improve with clearer, more consistent care.
Concord, New South WalesAges 18 years+ - NCT06361108RecruitingPhase 1
Spray study for diabetic nerve pain in feet
This study tests a new spray medication (YJ001) applied to the feet to see if it is safe and helps reduce pain in people with diabetic peripheral neuropathy. You may qualify if you have diabetes, stable blood sugar, and moderate to severe nerve pain in your feet.
Fredericksburg, TexasAges 18–80 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Aurora, ColoradoAges Any age - NCT06195228RecruitingPhase 4
Real-world study of genetic types in advanced thyroid cancer
This study looks at how different genetic types of advanced thyroid cancer respond to treatment in real-world settings. It may help doctors choose the best therapy for you based on your tumor’s genetic makeup.
Fuzhou, FujianAges Any age - NCT06676046Recruiting
Study of rare cholesterol and fat disorders
This study looks at people with rare or unusual cholesterol, fat, or heart-related conditions. It helps researchers learn more about these disorders and improve testing. You do not need to have a known diagnosis to join initially.
Bethesda, MarylandAges 10–90 - NCT06675097Recruiting
Gas after abdominal surgery: how it affects recovery
This study looks at how having gas after abdominal surgery might affect your recovery. It aims to understand if passing gas sooner could help you feel better faster and leave the hospital sooner.
Nantes, Loire AtlantiqueAges 18 years+ - NCT06679270RecruitingPhase 3
Long-term safety study of metreleptin for partial lipodystrophy
This study tests the long-term safety of metreleptin for people with partial lipodystrophy. It is for those who already completed a related study and want to continue treatment.
Birmingham, AlabamaAges 13 years+ - NCT06672237RecruitingPhase 3
Study of NTLA-2001 for hereditary ATTR amyloidosis with nerve damage
This study is testing a new gene-silencing treatment called NTLA-2001 for people with hereditary ATTR amyloidosis that causes nerve damage. It works by stopping the body from making a faulty protein that builds up and harms nerves.
Buenos AiresAges 18–85 - NCT06671587RecruitingPhase 4
Testing insulin/GLP-1 combo with CGM for type 2 diabetes
This study tests a combination insulin/GLP-1 medicine (iGlarLixi) with continuous glucose monitoring to see how well it controls blood sugar in Chinese adults with type 2 diabetes. It may help those whose current pills are not working enough.
BeijingAges 18 years+ - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06671236RecruitingPhase 1
Treg cell therapy for ALS
This trial tests a new type of cell therapy called regulatory T cells (Tregs) for people with neurodegenerative diseases like ALS. The goal is to see if these cells can slow down the disease.
Zhengzhou, HenanAges 18–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.