Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06507878Recruiting
Registry for advanced thyroid cancer treatments
This study collects real-world information from patients with advanced thyroid cancer to better understand how standard treatments and specialized procedures work. Your participation will help improve care for others with this type of cancer.
Houston, TexasAges 18 years+ - NCT06503809Recruiting
Ketogenic diet study for type 1 diabetes
This study tests if a very low-carb (ketogenic) diet is safe and helps control blood sugar in people with type 1 diabetes. You would follow the diet for a period and use a continuous glucose monitor to track your levels.
St Louis, MissouriAges 18–65 - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06507722Recruiting
Night Owl Metabolism Study
This study from Johns Hopkins looks at how your body's metabolism works when you're an overweight teen or young adult who sleeps enough. It aims to learn more about your 'night owl' internal clock and how it affects your health.
Baltimore, MarylandAges 18–23 - NCT06504433Recruiting
Natural history of mitochondrial diseases
This study follows people with mitochondrial disease over time to learn more about how the condition progresses. It may help researchers find better ways to manage and treat mitochondrial diseases in the future.
Randwick, New South WalesAges 18 years+ - NCT06509776Enrolling by invitation
Bone growth and hormone health in young adults
This study looks at how bones mature and how hormones change as you become a young adult. If you were born in Denmark in 2006 or 2007 and are 18, you may be invited to help researchers understand these changes.
AalborgAges 18–19 - NCT06510764RecruitingPhase 3
Chinese medicine and acupuncture for early puberty in girls
This trial tests if Chinese traditional medicine plus intradermal acupuncture can help treat early puberty (precocious puberty) in girls. It aims to slow down puberty that started too soon, avoiding the need for stronger medications.
Shanghai, Shanghai MunicipalityAges 4–9 - NCT06500104Enrolling by invitation
Kefir for Childhood Obesity: A Trial
This trial tests whether a probiotic drink called kefir (a fermented milk beverage) can help children and teens with obesity lose weight or improve their health. It's for children who are significantly above a healthy weight and don't have other serious medical conditions or dairy allergies.
TaichungAges 7–17 - NCT06500078Recruiting
Intermittent Diet for Heart Health in Kids
This study tests whether a special diet pattern (eating less at certain times) can improve heart health and blood sugar in school-aged children. It's for children who are overweight or have early signs of diabetes or heart risks.
ShanghaiAges 7–18 - NCT06513026Recruiting
Milk for diabetes prevention
This study tests whether drinking milk daily can help prevent type 2 diabetes in people with prediabetes and a specific gene variation. You'll be asked to drink milk or a placebo drink for several weeks while researchers monitor your blood sugar and health.
The Bronx, New YorkAges 18–70 - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70 - NCT06512818Enrolling by invitationPhase 1/Phase 2
Testing Psiguavin for weight loss in obesity
This study tests a natural supplement made from guava (called Psiguavin) to see if it helps with weight loss in people who are overweight or have obesity. Participants will take the supplement and be monitored for weight changes and safety.
MurciaAges 18–65 - NCT06496373RecruitingEarly Phase 1
mRNA vaccine plus immunotherapy after pancreatic cancer surgery
This trial tests a personalized mRNA vaccine combined with an immunotherapy drug (PD-1 inhibitor) to prevent pancreatic cancer from returning after surgery. It is for patients whose tumors have specific genetic features and who cannot have standard chemotherapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT01803451RecruitingEarly Phase 1
Tested after gastric bypass for low blood sugar
This early study looks at a gut hormone–based treatment (GLP-1) and how it affects blood sugar and digestion after gastric bypass. It may help people who are having repeated low blood sugar episodes after surgery.
San Antonio, TexasAges 18–65 - NCT00992901RecruitingEarly Phase 1
Testing hormones and nerve signals after gastric bypass
This early-phase study looks at how the body’s hormone signals and nerve control affect insulin release after gastric bypass surgery. It may help researchers understand what drives low blood sugar and how to better monitor or treat it.
San Antonio, TexasAges 18–65 - NCT06493084RecruitingPhase 1
Testing LAE102 in healthy and overweight adults
This study tests a new medicine called LAE102 in two groups: healthy volunteers and people who are overweight or obese. The goal is to see if it is safe and how the body processes it.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Los Angeles, CaliforniaAges Any age - NCT06491615Recruiting
eyeGENE study: genetics of rare eye diseases
This study collects DNA samples and medical information from people with rare inherited eye diseases and their close relatives. The goal is to learn more about the genetic causes of these conditions and improve diagnosis and care.
Bethesda, MarylandAges 1 day–120 years - NCT05107674RecruitingPhase 1
Early drug study for advanced cancers that have limited options
This Phase 1 study tests NX-1607 in adults with advanced cancers that are hard to treat with standard care. It focuses on safety and early signs of how well the drug may work in specific cancer types.
Duarte, CaliforniaAges 18 years+ - NCT06373913Recruiting
PCSK9's role in kidney damage in nephrotic syndrome
This study looks at how a protein called PCSK9 might affect kidney damage in people with nephrotic syndrome. It is for adults admitted to Kolding Hospital and aims to better understand the link between this protein and kidney problems.
KoldingAges 18 years+ - NCT06483048RecruitingPhase 1
MUC1-targeted T cells for relapsed ovarian cancer
This trial tests a new treatment using your own immune cells, modified to target a protein called MUC1 on ovarian cancer cells. It is for people with ovarian cancer that has come back or is resistant to standard treatments.
Scottsdale, ArizonaAges 18 years+ - NCT06484621Recruiting
Preventing weight regain after weight loss surgery with exercise
This study looks at whether increased physical activity can help prevent weight regain after weight loss surgery. It is for people who had gastric bypass or sleeve gastrectomy in the last 6–20 months and have regained less than 10% of their lost weight.
Hartford, ConnecticutAges 18–64 - NCT06489262Recruiting
Healthy Together (Juntos) program for Hispanic teens
This study tests a program called Healthy Together (Juntos) to help Hispanic teens and their parents make healthier choices about activity, eating, and screen time. Families who join will get support to improve their habits.
Miami, FloridaAges 12–15
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.