Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06519448Enrolling by invitation
Testing a pill for non-alcoholic fatty liver disease
This trial tests a diabetes drug called empagliflozin to see if it can reduce fat and inflammation in the liver in people with a specific type of fatty liver disease called NASH. It may help if you have NASH and either have type 2 diabetes or don't have it.
PragueAges 18–75 - NCT06524388Enrolling by invitation
Cognitive training study for older adults with diabetes
This study tests if a special computer-based brain training program can help improve thinking and memory in older adults with diabetes who are at risk for dementia. It might help keep your mind sharp as you age.
BeijingAges 60 years+ - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06527664Recruiting
Custom hip implant for failed arthritis treatments
This trial tests a custom-made hip socket implant for people who have had a failed hip replacement or arthritis treatment. It aims to see if a personalized implant can provide a better solution.
BolognaAges 18 years+ - NCT06516614Recruiting
Sleep coaching for teens with type 1 diabetes
This study is testing a sleep coaching program for teenagers with type 1 diabetes who aren't getting enough sleep and have above-target blood sugar. The program aims to help them sleep better and possibly improve diabetes control.
Nashville, TennesseeAges 11–17 - NCT06526273Recruiting
PILI 'Āina Household Program
This study is for Native Hawaiian adults living in homestead communities who are overweight or have health conditions like diabetes, high blood pressure, or high cholesterol. It looks at a household-based program to help you and your family make healthier lifestyle changes together.
Honolulu, HawaiiAges 18 years+ - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT06515613RecruitingPhase 1
Testing CTIM-76 for recurrent ovarian and other advanced cancers
This trial tests a new drug, CTIM-76, in people whose ovarian, testicular, or endometrial cancer has come back and is not responding to standard treatments. It aims to see if the drug can shrink tumors or stop them from growing.
Little Rock, ArkansasAges 18 years+ - NCT06525636RecruitingPhase 1/Phase 2
Study of a new drug for X-linked hypophosphatemia
This study tests an investigational drug called KK8123 for adults with X-linked hypophosphatemia (XLH), a rare condition that causes low phosphate levels and can lead to bone problems. The goal is to see if it helps improve phosphate levels in the body.
San Francisco, CaliforniaAges 18–65 - NCT05932862RecruitingPhase 1
Test drug XL309 for advanced tumors with HRR gene changes
This early-phase study tests XL309 (and sometimes a mix of XL309 with another treatment) in people whose advanced solid tumors have specific DNA-repair gene changes, such as BRCA1/2 or other HRR-related changes. It aims to see how well the drug works and what dose is safest for these cancers.
Fountain Valley, CaliforniaAges 18 years+ - NCT03977207Recruiting
Thyroid hormone supplement for people on dialysis
This trial tests whether taking a thyroid hormone supplement helps people who are on hemodialysis and have borderline-high thyroid lab results (high TSH but normal FT4). It’s studying whether treatment changes thyroid-related outcomes or health while on dialysis.
Orange, CaliforniaAges 18–75 - NCT04475666Recruiting
Protein replacement through tube feeding in ICU patients
This study tests whether giving a different protein through tube feeding can help critically ill adults in the ICU. You may be eligible if you are already receiving nutrition through a stomach or gut tube and are on a breathing machine.
Jeddah, JeddahAges 18 years+ - NCT05469087Recruiting
Study of primary hyperparathyroidism in adults
This study follows adults with primary hyperparathyroidism (a hormone-related condition that affects calcium levels). It aims to better understand the condition and who it affects, which may help improve care over time.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06503146RecruitingPhase 2
New imaging tracer for detecting various cancers
This trial tests a new imaging agent, [18F]FAPI-74, which might help detect certain cancers more clearly. The scan looks for a protein called fibroblast activation protein (FAP) that is often found in tumors. If you have one of the listed cancers and are about to start treatment, this study could help doctors see where the cancer is and how it responds to therapy.
Bethesda, MarylandAges 18–120 - NCT06497595Recruiting
Lifestyle program to prevent muscle loss in older adults with diabetes on semaglutide
This trial tests whether a lifestyle program (diet and exercise) can help prevent muscle loss in people 65 and older with type 2 diabetes and obesity who are taking semaglutide. It may help you keep your strength and independence while losing weight.
Jerusalem, IsraelAges 65 years+ - NCT06500052RecruitingPhase 1
Study of BL-M17D1 for HER2-positive or low-expression digestive tract and other solid tumors
This trial tests a new drug called BL-M17D1 for people with advanced or metastatic HER2-positive or low-expression gastrointestinal cancer and other solid tumors. The goal is to see if it is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT06501443RecruitingPhase 4
Study of inclisiran after heart attack or stroke
This study tests a cholesterol-lowering injection (inclisiran) given soon after a heart attack, urgent heart procedure, or stroke. The goal is to see if it helps lower bad cholesterol quickly and safely.
CorrientesAges 18–100 - NCT06496243RecruitingPhase 2
Testing new drugs to lower Lp(a) cholesterol
This study tests two new drugs, alone and together, to lower a type of cholesterol called Lp(a) that increases heart disease risk. You may qualify if you have high Lp(a) and your LDL cholesterol is still high despite current treatment.
Philadelphia, PennsylvaniaAges 18–75 - NCT06504147RecruitingPhase 2
Radspherin for ovarian cancer with peritoneal spread
This trial tests a radioactive treatment called Radspherin given during surgery for advanced ovarian cancer that has spread to the lining of the abdomen. It is for people whose tumors are HR proficient (a specific genetic type) and who have already had chemotherapy before surgery.
Tampa, FloridaAges 18 years+ - NCT06506643RecruitingPhase 1/Phase 2
Study of KLS-1 for solid tumors and CLL
This trial tests a new drug called KLS-1 for people with solid tumors (like melanoma, pancreatic, or prostate cancer) or chronic lymphocytic leukemia (CLL) that is no longer responding to standard treatments. The goal is to see if KLS-1 is safe and can shrink tumors or slow the cancer.
KropyvnytskyiAges 18 years+ - NCT06504043Enrolling by invitationPhase 1
Safety study of HST101 in healthy Chinese adults with high cholesterol
This study tests a new drug, HST101, to see if it is safe for healthy Chinese people with high cholesterol. It is an early-phase trial, so it focuses on safety first.
Chengdu, SichuanAges 18–55 - NCT06288568Recruiting
Night shift work and obesity risk study
This study looks at how night shift work affects weight and health in hospital and factory workers. They want to see if working nights changes your body's hormones and risk for obesity.
Vienna, State of ViennaAges 21 years+ - NCT06503809Recruiting
Ketogenic diet study for type 1 diabetes
This study tests if a very low-carb (ketogenic) diet is safe and helps control blood sugar in people with type 1 diabetes. You would follow the diet for a period and use a continuous glucose monitor to track your levels.
St Louis, MissouriAges 18–65 - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.