Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06289348Recruiting
How is PKU announced to families after newborn screening?
This study talks to parents or doctors about how they first learned their child had PKU through newborn screening. It aims to improve how these rare metabolic diseases are communicated to families.
ParisAges 18 years+ - NCT06287736Recruiting
Spinal cord stimulation for diabetic nerve pain
This study tests whether a spinal cord stimulator (a device that uses mild electrical pulses to block pain signals) can help people with diabetic nerve pain that hasn't responded to other treatments. If you have long-term nerve pain from diabetes and other pain meds haven't worked, this trial might be an option for you.
Columbus, OhioAges 18 years+ - NCT06283576Enrolling by invitation
Pancreatic cancer early detection with blood test
This trial studies a blood test to find pancreatic cancer early. It may help people who are at risk or have suspicious signs.
StockholmAges 18 years+ - NCT06285968Recruiting
Sleep health study for better heart health
This study tests whether improving sleep can help lower blood pressure and improve heart health. It is for adults with slightly elevated blood pressure and poor sleep who have not had heart disease or cancer.
New York, New YorkAges 30 years+ - NCT06278285Recruiting
GLP-1 drug effect on fat tissue before bariatric surgery
This study looks at how taking a GLP-1 medicine (like Ozempic or Wegovy) affects your fat tissue before bariatric surgery. It compares people who have taken a GLP-1 for at least 3 months to those who never have.
Nice, Alpes-maritimesAges 18 years+ - NCT06293703Recruiting
Leg length ratio and weight loss after gastric bypass
This study looks at how the length of different parts of your small intestine affects weight loss after Roux-en-Y gastric bypass surgery. It may help doctors tailor the surgery for better results.
Cleveland, OhioAges 18–70 - NCT06290193RecruitingPhase 2
Blood thinning before surgery for ovarian cancer
This trial tests if removing some blood before surgery and replacing it with fluids can reduce the need for transfusions in people with advanced ovarian cancer. It may help you have less blood loss during your operation.
Basking Ridge, New JerseyAges 18 years+ - NCT06280560Recruiting
IVF hormones and womb lining health study
This study looks at how IVF hormone treatments affect the womb lining and whether they cause aging cells to build up. It may help doctors improve IVF success rates.
Valencia, ValenciaAges 18–45 - NCT06282055Recruiting
Insulin sensitivity changes during menstrual cycles in type 1 diabetes
This study looks at how insulin sensitivity changes during the menstrual cycle in women with type 1 diabetes. It may help find patterns that could improve diabetes care.
BernAges 18–40 - NCT06285396Recruiting
Diabetes and medication effects on uterine muscle during C-section
This trial studies how three medications (ephedrine, phenylepinephrine, and norepinephrine) affect the contraction strength of uterine muscle tissue from pregnant people with type 2 or gestational diabetes during planned C-sections. It aims to understand if these drugs act differently in people with diabetes, which could help tailor safer treatments for low blood pressure during surgery.
Toronto, OntarioAges 19–45 - NCT06292598Recruiting
Gut bacteria and sleep disorder study
This study compares gut bacteria and substances from the gut in people with type 1 narcolepsy versus those without. It aims to understand how gut health might be linked to this sleep disorder.
Nîmes, GardAges 10 years+ - NCT06291155RecruitingPhase 4
How SGLT2 inhibitors work in the kidneys for type 2 diabetes
This study tests how a drug called canagliflozin (an SGLT2 inhibitor) affects kidney function in people with type 2 diabetes. It involves two kidney biopsies to see how the drug works inside your kidneys, aiming to better protect kidney health.
Ann Arbor, MichiganAges 18–80 - NCT06277362Recruiting
New Leg-Saving Treatment for Critical Limb Ischemia
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Ancona, AnconaAges 18 years+ - NCT06277661Recruiting
Mom and Infant Outcomes Study
This study tests a program to support pregnant people who have had high blood pressure, diabetes, or depression/anxiety. It aims to improve outcomes for both mothers and babies.
Columbus, OhioAges Any age - NCT05803018RecruitingPhase 1/Phase 2
Study drug for advanced gynecologic cancer that stopped working
This Phase 1/2 study tests BL-B01D1 in people with recurrent or metastatic gynecologic cancers (such as ovarian, uterine, or cervical cancer) when standard treatments have failed or aren’t options. It focuses on how well the drug works and whether it can be given safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT05787808Recruiting
Preventive treatment for people with early bone loss
This trial studies a preventive treatment for people over 55 who have early bone thinning (called osteopenia). If you qualify, it may help reduce the risk of getting osteoporosis and related fractures.
Skjetten, AkershusAges 55–85 - NCT06261190Enrolling by invitation
Active monitoring for low-risk thyroid cancer
This trial tests whether it is safe to avoid immediate surgery and instead monitor small thyroid cancers that are considered low-risk. If you join, doctors will check regularly to make sure the cancer does not grow or spread.
Goyang-siAges 18 years+ - NCT06270758Recruiting
Bone health check for women after menopause (BBCT-hip)
This study is testing a new way to check bone health in women who have gone through menopause and live in the Emilia-Romagna region of Italy. It aims to help predict and prevent hip fractures.
BolognaAges 65–85 - NCT06264609Enrolling by invitationPhase 4
Precision follow-up study for osteoporosis treatment
This study is a follow-up for people who completed a previous precision medicine trial for osteoporosis. It will monitor your bone health to see how well the treatment is working over time.
Lexington, KentuckyAges 45 years+ - NCT06271200Recruiting
Lifestyle change and medication for metabolic syndrome
This trial tests a lifestyle program combined with two medications (semaglutide and dapagliflozin) to help people with metabolic syndrome lose weight and improve their health. It may be an option if you are an adult with a BMI of 27 to 45 and have metabolic syndrome.
Zhunan, Miaoli CountyAges 20–65 - NCT06271317Recruiting
Complications after sleeve gastrectomy study
This study looks at complications after a type of weight-loss surgery called sleeve gastrectomy (removing part of the stomach). If you are considering this surgery and meet the weight/health guidelines, you may be able to join to help doctors learn more about risks and recovery.
Nantes, NantesAges 18 years+ - NCT06270498RecruitingPhase 4
Oral iron for heart failure: exercise and quality of life study
This study tests whether an oral iron supplement (a pill called sucrosomial iron) can help people with heart failure who have low iron feel better, have more energy, and walk farther. Participants will take the iron pill or a placebo (a pill without the active ingredient) for a period and will do exercise tests and answer questionnaires to see how they improve.
Pisa, TuscanyAges 18 years+ - NCT06268665RecruitingPhase 2
Tart Cherry Juice for Preventing Nerve Damage from Chemotherapy
This study tests whether tart cherry juice can help prevent nerve damage (peripheral neuropathy) caused by the chemotherapy drug paclitaxel. Participants drink tart cherry juice daily during their 12 weeks of paclitaxel treatment.
Sacramento, CaliforniaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.