Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06266689Recruiting
Dietary data return for infants
This study asks parents to collect and mail in stool samples from their infant over the next two years. Researchers want to learn more about how diet affects baby health.
Durham, North CarolinaAges Up to 1 year - NCT06257771Recruiting
Alcohol and gastric sleeve surgery study
This study looks at how alcohol affects people who have had gastric sleeve surgery (a type of weight loss surgery) compared to those who haven't. It may help explain if surgery changes how your body processes alcohol.
Urbana, IllinoisAges 21–64 - NCT06268665RecruitingPhase 2
Tart Cherry Juice for Preventing Nerve Damage from Chemotherapy
This study tests whether tart cherry juice can help prevent nerve damage (peripheral neuropathy) caused by the chemotherapy drug paclitaxel. Participants drink tart cherry juice daily during their 12 weeks of paclitaxel treatment.
Sacramento, CaliforniaAges 18 years+ - NCT06271291Recruiting
Pancreatic Cancer Detection Study for High-Risk People
This study looks for people at high risk for pancreatic cancer, either because of family history, certain genetic mutations, or concerning pancreatic cysts. Researchers want to follow you over time to find cancer early, when it's easier to treat.
Scottsdale, ArizonaAges 18 years+ - NCT06271200Recruiting
Lifestyle change and medication for metabolic syndrome
This trial tests a lifestyle program combined with two medications (semaglutide and dapagliflozin) to help people with metabolic syndrome lose weight and improve their health. It may be an option if you are an adult with a BMI of 27 to 45 and have metabolic syndrome.
Zhunan, Miaoli CountyAges 20–65 - NCT06273644Recruiting
Carbohydrate-rich diet for acute intermittent porphyria
This trial tests whether a diet high in carbohydrates can help treat acute intermittent porphyria (AIP), a condition that can cause attacks of pain and other symptoms. If you have AIP, this study wants to see if eating more carbs can prevent or manage attacks.
Bodø, NordlandAges 18 years+ - NCT06263088Recruiting
Equity in GI Cancer Care Study
This trial is looking for Black patients newly diagnosed with any stage of gastrointestinal cancer to help improve cancer care and make sure research includes everyone. By joining, you help doctors learn how to better support patients like you.
Cleveland, OhioAges 18 years+ - NCT06271317Recruiting
Complications after sleeve gastrectomy study
This study looks at complications after a type of weight-loss surgery called sleeve gastrectomy (removing part of the stomach). If you are considering this surgery and meet the weight/health guidelines, you may be able to join to help doctors learn more about risks and recovery.
Nantes, NantesAges 18 years+ - NCT06263868Recruiting
First study tracking early puberty signs
This study observes children who show signs of puberty earlier than usual. It aims to better understand early and advanced puberty by tracking children's development.
Écully, Auvergne-Rhône-AlpesAges Up to 11 years - NCT06256991RecruitingPhase 4
Potassium management for kidney health
This study tests if careful potassium management can help people with chronic kidney disease (CKD) safely take higher doses of blood pressure medicines called ACE inhibitors or ARBs, which are known to protect the kidneys. You may be eligible if you have moderate to advanced CKD and are already on a moderate dose of one of these medications.
GroningenAges 18 years+ - NCT06274788Recruiting
Safety study of long-term Omegaven for liver problems from IV nutrition
This study checks if children who need Omegaven for eight weeks or longer develop a lack of essential fats. It is for kids with liver issues caused by IV nutrition who cannot eat or digest food normally.
Fountain Valley, CaliforniaAges 1 day–17 years - NCT06270316RecruitingPhase 1/Phase 2
Gene therapy for classic Fabry disease
This trial tests a one-time gene therapy called AMT-191 for men with classic Fabry disease who are still having symptoms despite enzyme replacement therapy. The goal is to see if it can reduce pain and stomach problems and improve overall health.
Birmingham, AlabamaAges 18–65 - NCT06270706RecruitingPhase 1
Study of a new drug for advanced solid tumors after immunotherapy
This study tests a new drug called PLN-101095 in people with advanced solid tumors whose cancer has stopped responding to a common immunotherapy. The goal is to see if combining this new drug with pembrolizumab can help control the cancer again.
New Haven, ConnecticutAges 18 years+ - NCT05867979Recruiting
Find hidden DNA changes in some boys with unclear DSD
This trial looks for “structural variants,” meaning larger DNA rearrangements that standard gene tests may miss, in boys with certain differences in sex development (DSD) when results are unclear. It may help provide a clearer diagnosis that can guide care for your family.
MontpellierAges 6 months+ - NCT06252220RecruitingPhase 1
Testing a new drug for obesity in healthy adults
This trial tests a new medication called DA-1726 for people with obesity but no other major health problems. It aims to see if the drug is safe and how it works in the body. You may qualify if your body mass index (BMI) is between 30 and 45 and your weight has been stable for 3 months.
Miami, FloridaAges 18–65 - NCT06234423RecruitingPhase 1
A study of CUSP06 for advanced solid tumors
This study tests a new drug called CUSP06 for people with advanced solid tumors, especially ovarian cancer that has stopped responding to platinum chemotherapy. It may help if standard treatments no longer work.
Denver, ColoradoAges 18 years+ - NCT06247085RecruitingPhase 3
A study testing pegtibatinase for classical homocystinuria
This trial tests an injectable drug called pegtibatinase for people with a rare condition called homocystinuria. It aims to lower high levels of homocysteine in the blood compared to a placebo, while you continue your usual treatments.
Phoenix, ArizonaAges 12–65 - NCT06242470RecruitingPhase 1
Study of MGC026 for advanced solid tumors
This trial tests a new drug called MGC026 that targets a protein called B7-H3 on cancer cells, aiming to shrink or slow different advanced solid tumors. It is an early-phase study to find the right dose and check safety.
Los Angeles, CaliforniaAges 18 years+ - NCT06249412Recruiting
Positive pressure breathing device for ALS patients
This trial tests whether a mask that helps you breathe out (positive expiratory pressure) combined with a cough-assist machine (in-exsufflator) improves breathing and coughing in people with ALS who have bulbar symptoms like trouble speaking, swallowing, or drooling.
Le Havre, NormandyAges 18–100 - NCT06246799RecruitingPhase 3
Comparing two pill combinations for new diabetes
This study compares two different two-drug combinations for people recently diagnosed with type 2 diabetes. It aims to find which combination works better to control blood sugar and improve overall health.
San Antonio, TexasAges 18–75 - NCT06230510Recruiting
Whole vs. low-fat milk study for toddlers
This study compares the health effects of drinking whole milk versus 1% low-fat milk for one year in children aged 23 to 48 months. Researchers want to see which type of milk is better for growth and overall health.
Oakland, CaliforniaAges 1.9 years–4 years - NCT06249867RecruitingPhase 2
Study of darifenacin for people with ALS
This trial tests a medication called darifenacin (usually used for bladder problems) in people with ALS, to see if it is safe and if it might help slow the disease. If you join, you will take the study drug or a placebo and be closely monitored.
Ottawa, OntarioAges 18–85 - NCT06251778Recruiting
National study of ATTR heart amyloid patients on tafamidis
This study follows patients with a specific type of heart amyloidosis (wild-type ATTR) who are taking or could start the drug tafamidis. It aims to learn more about how the condition and treatment affect people over time.
PaviaAges 18–99 - NCT06238700Recruiting
Studying allopregnanolone for depression in midlife women
This trial tests whether allopregnanolone, a natural brain chemical, can help depression in women going through menopause. It compares the effects against a placebo to see if it improves mood symptoms.
Boston, MassachusettsAges 40–60
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.