Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05919940Recruiting
Testing a muscle stimulation and extra protein plan in ICU patients
This trial tests whether electrical muscle stimulation plus extra protein (protein substitute) can improve muscle health and metabolism in critically ill adults in the ICU. If you’re newly admitted and expected to stay on a breathing machine for several days, it may help you keep more muscle strength during recovery.
Vienna, State of ViennaAges 18 years+ - NCT05933707Recruiting
Study tiny vesicles and how they affect insulin
This study looks at how very small particles in the body (“extracellular vesicles”) relate to insulin action and how the body handles sugar. It may help researchers understand why some people have better or worse insulin responses.
St Louis, MissouriAges 25–55 - NCT05924295Recruiting
Study how ketone changes in the body with diet and fasting
This study looks at how your body processes “ketones,” which are energy molecules that rise with fasting or low carbohydrate intake. You may be asked to follow strict diet and activity rules before test days so researchers can see what affects ketone metabolism.
Novato, CaliforniaAges 20–70 - NCT05768178RecruitingPhase 2/Phase 3
Vemurafenib plus cobimetinib for BRAF-mutant cancers
This trial tests whether combining two targeted cancer medicines—vemurafenib and cobimetinib—can treat adults whose tumors have a specific “BRAF V600” mutation. You may be screened with blood tests and a tissue biopsy before starting treatment.
BelfastAges 18 years+ - NCT05389098Recruiting
Finger foods program to help eating in frail seniors
This study tests whether offering easy “finger foods” can improve eating and independence in older adults living in assisted care. It is looking especially at people who are losing weight, have low muscle strength, and may struggle to chew or swallow.
Château-RenaultAges 75–120 - NCT05908708Recruiting
Testing a closed-loop insulin system for kids with type 1 diabetes
This trial studies how the Medtronic 780G “closed-loop” insulin system works for young people with type 1 diabetes. It may help by improving how automatically insulin is delivered, depending on your body’s needs.
Ramat Gan, Please SelectAges 1–21 - NCT05881005Recruiting
NAC for fatty liver in people with active Cushing’s
This study tests whether NAC (a supplement/medicine) can improve liver health in adults who have active Cushing’s syndrome and fatty liver disease. It may help if your excess stress hormone levels are affecting your liver.
AngersAges 18 years+ - NCT05901077Recruiting
European cystinosis patient follow-up study
This study follows people with confirmed cystinosis to better understand the condition. It mainly checks that you have the right diagnosis and can join voluntarily.
Paris, Île-de-France RegionAges Any age - NCT05880108Recruiting
Behavior program to help COVID recovery in Veterans
This study tests whether a behavioral (lifestyle) program can improve recovery from COVID-19, especially for Veterans with different body weights. It looks at people who either have never had COVID before or had COVID more than 90 days ago.
Baltimore, MarylandAges Up to 80 years - NCT05899231Recruiting
Online strengthening program while you wait for a liver transplant
This trial tests an online prehabilitation program (strength and fitness training delivered digitally) to help people who are likely to need a liver transplant become stronger before transplant. It may benefit people who feel “frail” or “pre-frail,” since improving strength before surgery can help recovery.
Calgary, AlbertaAges 18 years+ - NCT05899023Recruiting
Diabetes screening after an ER visit
This trial checks for signs of diabetes using a blood test (HbA1c) after an emergency room visit, then links eligible people to outpatient care. It may help you find diabetes earlier and get follow-up treatment sooner.
New York, New YorkAges 20–70 - NCT05896293RecruitingPhase 2
Kisspeptin shots for low hormone condition
This study tests if a hormone called kisspeptin can help people with a condition that limits sex hormones. The trial involves regular shots under the skin.
Boston, MassachusettsAges 18 years+ - NCT05878314Recruiting
Testing how hormones and tumor markers guide breast cancer treatment
This study looks at how planned hormone (endocrine) treatment, the menstrual cycle, and lab markers from the tumor may help doctors choose the best treatment for early-stage, hormone-receptor–positive, HER2-negative breast cancer. It may help personalize decisions, including what to do before surgery.
TübingenAges 18 years+ - NCT05880914Recruiting
Personalized treatment study for bone disease in kidney failure
This trial looks at a personalized approach to diagnosing and treating bone problems caused by long-term kidney disease. It may help by matching treatment plans to the type of bone turnover found in your tests or biopsy.
St Louis, MissouriAges 18 years+ - NCT05880758Recruiting
Studies how yo-yo sleep affects heart and metabolism health
This study looks at what happens to heart-related health and body metabolism when your sleep goes through ups and downs (yo-yo sleep). You may be asked about your sleep habits and health history to see whether your body changes in response to different sleep patterns.
New York, New YorkAges 18–49 - NCT05903131RecruitingPhase 2
Lifestyle program to help keep the uterus in early cancer
This Phase 2 study tests whether a lifestyle transformation can help treat complex atypical endometrial hyperplasia or early (grade 1) endometrial cancer without removing the uterus. It may help support uterine preservation for people who want to keep fertility or avoid hysterectomy.
St Louis, MissouriAges 18 years+ - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05898646RecruitingPhase 2
Daratumumab maintenance for AL amyloidosis after initial treatment
This Phase 2 trial studies whether giving daratumumab as ongoing maintenance therapy after your initial AL amyloidosis treatment can improve survival. It may help by keeping the disease under control longer after you have responded to induction therapy.
Scottsdale, ArizonaAges 18 years+ - NCT05901233Enrolling by invitation
Remote brain stimulation and speech therapy for primary progressive aphasia
This study tests whether combining speech-language treatment with remotely supervised brain stimulation (a mild current to the scalp) can improve communication in people with primary progressive aphasia. You and a study partner would also join online training and regular video check-ins.
San Francisco, CaliforniaAges Any age - NCT05880810Recruiting
Home patients with diabetes trial a continuous glucose monitor
This study tests a continuous glucose monitor (a sensor that tracks glucose) for people with type 1 or type 2 diabetes who receive care at home through Mayo’s Advanced Care at Home program. It may help by improving how safely and accurately blood sugar is followed while you’re at home.
Jacksonville, FloridaAges 18 years+ - NCT05888532RecruitingPhase 1/Phase 2
Testing a copper-based scan and treatment in advanced cancers
This Phase 1/2 trial studies a copper-labeled medicine called 64Cu-GRIP B in people with advanced, metastatic cancers. It may help doctors see where cancer is and how well the drug works, especially alongside immune checkpoint therapy for some cancer types.
San Francisco, CaliforniaAges 18 years+ - NCT05899439Recruiting
Blood test study of immune changes in type 1 diabetes
This study looks at how your immune system changes over time and how that relates to developing type 1 diabetes. You may be able to join if you can have blood drawn, since the study focuses on blood samples.
Gainesville, FloridaAges birth–100 years - NCT05909046Recruiting
Diabetes screening after childbirth and follow-up care study
This study checks how well diabetes screening done right after delivery works, and then offers follow-up care for participants later after birth. It may help you catch ongoing diabetes risk early and connect you to the right care.
Columbus, OhioAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.