Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05899023Recruiting
Diabetes screening after an ER visit
This trial checks for signs of diabetes using a blood test (HbA1c) after an emergency room visit, then links eligible people to outpatient care. It may help you find diabetes earlier and get follow-up treatment sooner.
New York, New YorkAges 20–70 - NCT05888532RecruitingPhase 1/Phase 2
Testing a copper-based scan and treatment in advanced cancers
This Phase 1/2 trial studies a copper-labeled medicine called 64Cu-GRIP B in people with advanced, metastatic cancers. It may help doctors see where cancer is and how well the drug works, especially alongside immune checkpoint therapy for some cancer types.
San Francisco, CaliforniaAges 18 years+ - NCT05880914Recruiting
Personalized treatment study for bone disease in kidney failure
This trial looks at a personalized approach to diagnosing and treating bone problems caused by long-term kidney disease. It may help by matching treatment plans to the type of bone turnover found in your tests or biopsy.
St Louis, MissouriAges 18 years+ - NCT05880810Recruiting
Home patients with diabetes trial a continuous glucose monitor
This study tests a continuous glucose monitor (a sensor that tracks glucose) for people with type 1 or type 2 diabetes who receive care at home through Mayo’s Advanced Care at Home program. It may help by improving how safely and accurately blood sugar is followed while you’re at home.
Jacksonville, FloridaAges 18 years+ - NCT05880758Recruiting
Studies how yo-yo sleep affects heart and metabolism health
This study looks at what happens to heart-related health and body metabolism when your sleep goes through ups and downs (yo-yo sleep). You may be asked about your sleep habits and health history to see whether your body changes in response to different sleep patterns.
New York, New YorkAges 18–49 - NCT05904626RecruitingPhase 2
ELGN-2112 safety study for very preterm and small babies
This Phase 2 trial studies whether ELGN-2112 is safe in babies born very early or smaller than expected before birth. It may help doctors understand how to better care for these high-risk newborns.
NetanyaAges 1 day–5 days - NCT05884255RecruitingPhase 3
Lutetium brain-sparing therapy for advanced gut and pancreas tumors
This Phase 3 trial tests lutetium (Lu-177) oxodotreotide, a targeted treatment, for people with advanced gut and pancreas neuroendocrine tumors that are low or medium grade (G1 or G2). The study will see whether it helps control the cancer and symptoms in the right patients.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05897957Enrolling by invitation
Follow-up study for people who received BRT-DA01
This study is for people with Parkinson’s disease who previously took part in an earlier BRT-DA01 trial and finished it (or stopped it). It mainly checks how participants do over time after that earlier treatment.
Orange, CaliforniaAges 50–78 - NCT05883748Enrolling by invitationPhase 2/Phase 3
Long-term study of bitopertin for EPP safety and benefit
This trial studies how safe and well bitopertin works over the long term for people with EPP. It mainly includes people who already finished an earlier bitopertin study, to keep tracking side effects and overall progress.
Birmingham, AlabamaAges 12 years+ - NCT05454176RecruitingPhase 4
Diabetes monitoring support for African youth with type 1
This study helps children and young adults with type 1 diabetes in Uganda improve how their diabetes is tracked, likely by using an additional monitoring sensor. If you join, you’ll be asked to attend regular pediatric diabetes clinic visits and use the study monitoring device for part of the start period.
Minneapolis, MinnesotaAges 4–26 - NCT05867251RecruitingPhase 1/Phase 2
AVZO-021 for advanced breast and ovarian cancers
This early-stage study tests AVZO-021, a new anti-cancer medicine, in people with advanced solid tumors like specific types of breast and ovarian (or related) cancers. It’s meant to find the safest dose and look for signs the medicine can shrink tumors, especially in cancers with certain gene changes.
New Haven, ConnecticutAges 18 years+ - NCT05877599RecruitingPhase 1
Study of a new treatment for advanced cancers with a specific gene change
This trial tests a new type of therapy (NT-175) for people with certain advanced cancers that have a specific genetic change. It might help if your tumor has the TP53 R175H mutation and you have the HLA-A*02:01 immune marker.
Gilbert, ArizonaAges 18 years+ - NCT05872022Enrolling by invitation
Safety study of Wegovy exposure during pregnancy
This study tracks the safety of taking Wegovy during pregnancy. Researchers want to understand potential risks and outcomes when people are exposed to Wegovy in early or any stage of pregnancy.
Princeton, New JerseyAges 15–50 - NCT05866406Recruiting
Time-restricted eating to improve heart and sugar health
This study tests whether eating only within a set daily time window can improve cardiometabolic health (things like blood sugar and heart-related measures). You may be eligible if you have overweight and borderline/high-risk blood sugar but do not have diabetes and can follow the eating and testing rules.
CambridgeAges 25–75 - NCT05847478Recruiting
Acupressure vs eating plan breaks for specific stomach syndrome
This study compares ear (auricular) acupressure to an intermittent dietary restriction approach in children who have a particular “stomach heat and dampness” pattern from Traditional Chinese Medicine. The goal is to see which method better helps children with certain weight and blood-sugar or cholesterol risks.
ShanghaiAges 6–18 - NCT05869734Enrolling by invitation
Conservative care to improve urinary symptoms and sleep in diabetes
This study looks at a non-surgical (“conservative”) approach to help women with diabetes who have bladder-related urinary symptoms and poor sleep. It aims to see whether these symptoms improve at the same time, helping quality of life.
New Taipei CityAges 20–79 - NCT05852223RecruitingPhase 2
Pembrolizumab for high-risk thyroid cancer that cannot be fully removed
This study tests pembrolizumab (an immune therapy) in people with high-risk thyroid cancer that is hard to treat with surgery alone. It looks at whether this drug can reduce persistent or recurrent cancer after your planned treatment.
Pavia, LombardyAges 18 years+ - NCT05871164Recruiting
Long-term study of radiofrequency treatment for pancreatic tumors
This study follows adults over time who are treated for a pancreatic tumor using ultrasound-guided radiofrequency through a thin needle. It aims to understand what happens after treatment and how patients do, so future care can improve.
ToulonAges 18 years+ - NCT05849753Recruiting
Access program for diabetes tech in kids with type 1
This trial helps children with type 1 diabetes get advanced diabetes technology, aiming to reduce gaps in access for families with fewer resources. It will check whether these tools are usable and helpful for diabetes care in children who meet the study needs.
Jacksonville, FloridaAges 6–17 - NCT05861973Recruiting
Smartphone program to support weight loss
This study tests a smartphone app (“SMARTer”) to help adults manage weight. You may be able to join if you have overweight and are not already in a structured weight loss program.
Tallahassee, FloridaAges 18 years+ - NCT05847855Recruiting
Blood test to help detect certain early pancreatic tumors
This study looks at a special analysis of your blood (called cfDNA fragmentomics) to help find and tell apart certain early pancreatic tumors. If you’re having surgery for one of the listed solid pancreatic tumors, this trial may use your blood samples to improve diagnosis.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05850130Recruiting
Acupuncture for nerve pain after colon cancer treatment
This trial tests whether acupuncture can relieve the nerve pain and tingling in the hands and feet that often occurs after treatment with oxaliplatin, a chemotherapy drug for gastrointestinal cancers. The study aims to help people manage this side effect and improve their daily comfort.
AmiensAges 18 years+ - NCT05857150Recruiting
Study tests exercise effects in adults with obesity
This study looks at how your body responds to exercise if you have obesity. It may help researchers understand which changes happen with exercise and how safe it is for people in your age group.
Rochester, MinnesotaAges 20–45 - NCT05869058Recruiting
Imaging test to check blood flow in parathyroid tissue
This trial evaluates a new imaging method during endoscopic thyroid surgery to detect and assess blood flow to nearby parathyroid tissue. Better detection of blood flow may help reduce the risk of parathyroid-related hormone problems after surgery.
Guangzhou, GuangdongAges 18–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.