Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05747976Recruiting
Study for children with very high body size measurements
This study is building a program database for children who have unusually high body size measurements for their age. By collecting genetic and health information, researchers hope to better understand causes of obesity and guide care.
Houston, TexasAges Any age - NCT05762432Recruiting
Wound dressing study for certain diabetic foot ulcers
This study looks at a specific wound dressing in people with a non-infected diabetic foot ulcer that has nerve pain (neuropathic), poor blood flow (ischemic), or both. It may help you heal the ulcer and improve how the wound looks and progresses.
Airdrie, North LanarkshireAges 18 years+ - NCT05746182Recruiting
Genetic testing program for pancreatic neuroendocrine tumors
This study offers genetic (inherited) testing for people with pancreatic neuroendocrine neoplasms. The goal is to see who may have a genetic predisposition, which can help guide medical care and family risk.
Los Angeles, CaliforniaAges 18 years+ - NCT05758467Enrolling by invitation
Study linking adult oral health, social factors, and heart health
This study looks at how people’s oral health in adulthood relates to social factors and heart health. To join, you must have already taken part in specific past health surveys.
BergenAges 71–72 - NCT05752448Recruiting
Care plan support for women after ovarian cancer treatment
This trial looks at survivorship care—how to help women after ovarian cancer treatment. It may improve follow-up planning and support during the first months after treatment ends.
Dallas, TexasAges 18 years+ - NCT05764733RecruitingPhase 4
How bone exercise, alendronate, and diet affect bone strength
This trial studies whether doing a structured bone-focused exercise program, taking alendronate (a medication that slows bone loss), and making a calorie-reducing diet can improve bone strength in people with low bone density. It also compares different combinations to see what helps most and is safest for you.
Aurora, ColoradoAges 60 years+ - NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT05752292Enrolling by invitation
Pregnant with gestational diabetes: share risk info to help
This study is testing how to share risk information during pregnancy in a way that helps patients feel more informed and empowered. It includes people currently pregnant with gestational diabetes and will ask about your preferences and understanding.
Pleasanton, CaliforniaAges 18 years+ - NCT05756829Recruiting
Virtual education program for adults with type 1 diabetes
This study tests a 6-month online education and support program to help adults manage type 1 diabetes using insulin pump therapy or multiple daily insulin shots. It may help you improve understanding, day-to-day decision-making, and diabetes self-care with ongoing check-ins.
Kitchener, OntarioAges 18 years+ - NCT05750667Enrolling by invitation
Family screening for familial high cholesterol
This trial is about helping families with familial hypercholesterolemia (a genetic condition that causes very high cholesterol) get screened. It tests a way to reach close relatives so they can learn their risk and consider next steps.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05747937Recruiting
Tracking nerve changes in people with ALS
This study follows people with ALS over time to learn how the body’s automatic nerves and nerve sensing (how you feel touch and pain) change. It may help researchers understand ALS better and guide future care.
Telese Terme, BeneventoAges 18 years+ - NCT05776563Recruiting
Testing whether brain sugar transport improves in type 2 diabetes
This study looks at whether the way the brain uses sugar (glucose) in people with type 2 diabetes can improve, and whether changes track with tighter diabetes treatment. You may get brain scans (MRI/MRS) and diabetes monitoring to see if there’s “reversibility” in the brain’s sugar transport.
New Haven, ConnecticutAges 18–60 - NCT05776212Recruiting
Imaging study for certain heart amyloidosis types and heart thickening
This trial uses special heart imaging to better measure how amyloid deposits affect the heart in people with certain diagnoses. The goal is to understand which imaging signals match your disease and to see if this approach could help guide care.
GroningenAges 40 years+ - NCT05765786Recruiting
Testing methods to diagnose variable primary aldosteronism
This study looks at better ways to diagnose primary aldosteronism when lab results suggest the condition but standard diagnosis criteria haven’t been met. It may help you understand what your hormone pattern means and whether you need specific treatment.
LondonAges 18 years+ - NCT05777330Recruiting
Monitoring blood sugar swings to predict type 1 diabetes
This study watches blood sugar changes over time in people who do not yet have diabetes but have test results that suggest risk for type 1 diabetes. The goal is to see whether “blood sugar variability” can predict when high or low blood sugar may happen, even before symptoms.
Liège, LiègeAges 5–39 - NCT03991897Recruiting
Keto diet to treat early arm swelling after lymph node removal
This study tests whether a ketogenic (keto) diet can reduce arm lymphedema (swelling) that started within the last year after lymph node removal. It aims to improve swelling by changing the body’s metabolism.
LeuvenAges 18 years+ - NCT05702463RecruitingPhase 1
Daily aspirin in adults with type 2 diabetes
This early-stage study tests how a daily aspirin tablet behaves in the body and how it affects blood/clotting markers in people with type 2 diabetes. It may help researchers understand whether this form of aspirin could be useful, especially if you’re not currently taking aspirin.
Montreal, QuebecAges 18 years+ - NCT04284969Recruiting
Study of surgery plan for advanced ovarian or peritoneal cancer
This trial looks at whether a specific treatment pathway that may include surgery helps people with advanced ovarian (or related) cancer. It mainly involves planning and undergoing a complex pelvic surgery, sometimes after chemotherapy, to improve outcomes.
BordeauxAges 70 years+ - NCT05739981RecruitingPhase 1/Phase 2
Immunotherapy plus chemo for newly diagnosed advanced ovarian cancer
This trial tests an immune-based treatment (IMNN-001/GEN-1) combined with standard chemotherapy given before and during surgery. It’s for people with newly diagnosed advanced high-grade serous ovarian, fallopian tube, or primary peritoneal cancer to see if it can improve outcomes.
Baltimore, MarylandAges 18 years+ - NCT05735080RecruitingPhase 1/Phase 2
INX-315 for advanced cancers with a specific gene change
This trial studies an experimental medicine (INX-315) given in an “open-label” way to people with advanced cancer that has not responded to prior treatment. It mainly looks at safety and side effects first, and also checks how well it works in cancers with a specific gene amplification.
Orlando, FloridaAges 18 years+ - NCT05732870Recruiting
Study looks for blood and gene signals that affect bone health
This study collects information and samples around the time of certain bone or joint surgeries (like joint replacement or fracture repair) to learn what factors help or harm bone healing. The results may help find better targets to improve long-term bone health and recovery.
London, Greater LondonAges 18–110 - NCT05718570Enrolling by invitation
Long-term follow-up for adults taking Sogroya for growth hormone deficiency
This study follows adults with growth hormone deficiency who start (or have started) Sogroya to learn about its long-term safety. It does not change your treatment—it mainly checks for side effects and health outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT05710692RecruitingPhase 2/Phase 3
Study drug PRX-102 for Fabry disease in Japanese patients
This trial tests whether PRX-102 is safe and effective for treating Fabry disease in Japanese participants. It also measures how the drug moves through the body and affects body systems, to see if it helps your symptoms and organ function.
Chikushino-shi, FukuokaAges 13–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.