Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,634 recruiting studies in this area right now.
By phase
- Not applicable5,355
- Phase 2606
- Phase 1561
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer88
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,634 total
- NCT05693220Recruiting
Sperm preparation for intrauterine insemination
This study looks at different ways to prepare sperm for intrauterine insemination (IUI), a fertility treatment where sperm is placed directly into the uterus. The goal is to see which preparation method leads to better outcomes for people trying to conceive.
San Francisco, CaliforniaAges 18 years+ - NCT05680012Recruiting
Testing how gluten affects healing in celiac disease
This study looks at how the gut lining “tissues” are affected during gluten eating versus avoiding gluten in people with celiac disease. It may help researchers understand what drives healing and tissue damage in celiac disease.
Pasadena, CaliforniaAges 18–75 - NCT05693701Recruiting
Lifestyle and study program for blood donors with high cholesterol
This study tests a multicomponent program for people who donate blood and have high cholesterol that fits familial hypercholesterolemia criteria. It may help lower cholesterol, but you must not already be on cholesterol-lowering medicines.
Dallas, TexasAges 18–75 - NCT05679674Recruiting
Radiation plus at-home tumor device for locally advanced pancreatic cancer
This trial tests whether combining targeted radiation with an at-home “tumor treating fields” device can better control locally advanced pancreatic cancer. It may help by attacking cancer cells in more than one way after prior chemotherapy.
Miami, FloridaAges 18 years+ - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Phoenix, ArizonaAges Any age - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05706155Recruiting
Switching some animal protein to plant protein for Type 2 diabetes
This study tests whether replacing part of your animal protein with plant-based protein can improve Type 2 diabetes control. It may help your blood sugar and weight management without changing everything about your diet.
Porto Alegre, Rio Grande do SulAges 18–65 - NCT05703347Recruiting
Mobile app coaching to improve sleep and prevent childhood obesity
This study tests a mobile health app that helps children get better sleep, aiming to support healthier weight over time. It is designed for children who are getting less sleep than recommended and are in the higher-but-not-highest weight range for their age.
Philadelphia, PennsylvaniaAges 8–12 - NCT05687604Recruiting
Telehealth program to reduce cancer risk behaviors
This trial offers a scalable telehealth (phone/video) program to help people improve cancer risk habits like low physical activity, higher body weight, and smoking. It may help by giving structured coaching and support in the privacy of your home.
Chicago, IllinoisAges 18 years+ - NCT05705804Recruiting
Comparing statins and ezetimibe for heart patients with metabolic syndrome
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
SeoulAges Any age - NCT05676970Recruiting
Telehealth coaching to improve preventive health decisions
This study tests a telehealth program that helps people make better choices about preventive health (like staying on track with healthy care). You may benefit if you can use a phone or computer for visits and want practical guidance delivered remotely.
New Orleans, LouisianaAges 18–55 - NCT05702931RecruitingPhase 4
Semaglutide for high blood sugar after kidney transplant
This trial tests semaglutide, a medicine that helps lower blood sugar, in people who develop high blood sugar shortly after a kidney transplant. It may help control blood sugar without harming the transplanted kidney, while also checking safety in this specific group.
CopenhagenAges 18–80 - NCT05704491Recruiting
AI screening for diabetic eye damage
This study tests an artificial intelligence (AI) screening method to detect diabetic retinopathy, a type of eye damage caused by diabetes. It may help find eye changes earlier, so treatment can be planned sooner.
DüsseldorfAges 18 years+ - NCT05688969Recruiting
Study of how an osteoporosis shot works in postmenopausal women
This study looks at what changes in the body after starting romosozumab (an osteoporosis treatment) in postmenopausal women at higher risk for fractures. Researchers want to understand the treatment’s “mechanism,” which may help improve future osteoporosis care.
Boston, MassachusettsAges 45 years+ - NCT01129297Recruiting
Severe obesity tissue study during surgery
This study collects small tissue samples during certain abdominal surgeries to better understand what drives severe obesity and related blood-sugar patterns. If you agree to the extra sampling, your information and samples may help researchers build a “biological atlas” that could guide future treatments.
Lille, NordAges 18–65 - NCT01241864RecruitingPhase 2
Islet transplant for type 1 diabetes after kidney transplant
This trial tests whether transplanting insulin-producing “islet” cells can better control blood sugar in people who have already received a kidney transplant. It’s mainly for adults with type 1 diabetes whose body is no longer making enough insulin, while they are on kidney-transplant medicines.
Chicago, IllinoisAges 18–68 - NCT04602754RecruitingPhase 3
Oral treatment test for type 2 diabetes and bad cholesterol
This Phase 3 study tests whether Berlim 25/20 can improve blood sugar control and cholesterol (LDL) in adults with type 2 diabetes who haven’t met targets despite prior lifestyle guidance and treatment. It also looks at safety, including effects on the heart and medication-related side effects.
Campinas, São PauloAges 18–85 - NCT05028140RecruitingPhase 3
Testing a lifestyle-and-diet program for type 2 diabetes control
This Phase 3 study tests whether a program run by the Piemonte Association can improve blood sugar control in people with type 2 diabetes who haven’t reached their target after usual diet, exercise, and stable medicines. It also aims to check that the approach is safe for participants.
Hortolândia, São PauloAges 18–85 - NCT02390973Recruiting
Bariatric-style surgery vs best diabetes care for long remission
This trial compares surgery plus follow-up care versus the best non-surgical (medical) treatment to help people keep type 2 diabetes in remission for a long time. It may be an option if you have higher body weight and diabetes that’s not well controlled, but safety checks are strict.
Québec, QuebecAges 18–60 - NCT05242835Recruiting
Study for weight regain after sleeve stomach surgery
This trial studies a specific type of metabolic (weight-related) surgery for people whose sleeve gastrectomy did not lead to enough weight loss or has caused significant weight regain. It may help improve long-term weight and related health problems.
Québec, QuebecAges 18–60 - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT05502016Recruiting
Diabetes education for Marshallese families
This study tests a family-based diabetes self-care education program offered at local places in the Marshallese community. It may help improve how people manage type 2 diabetes day to day by involving family members.
Springdale, ArkansasAges 18 years+ - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+ - NCT05652478RecruitingPhase 2
How HIV prevention drugs affect metabolism in healthy people
This study tests how certain HIV prevention drugs affect the body's metabolism (how it uses energy) in healthy people. It aims to understand side effects before these drugs are used more widely, which could help make future treatments safer.
Bethesda, MarylandAges 18–55
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,634 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,041 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.