Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,639 recruiting studies in this area right now.
By phase
- Not applicable5,357
- Phase 2608
- Phase 1562
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer112
- Overweight106
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,639 total
- NCT05317585Recruiting
Continuous glucose monitor use during early pregnancy with type 2 diabetes
This study tests whether using a continuous glucose monitor during pregnancy is useful for people with type 2 diabetes. It may help track blood sugar levels more closely to support safer pregnancy care.
Worcester, MassachusettsAges 18 years+ - NCT05348863Recruiting
Digital coaching for self-care in gestational diabetes
This trial studies a digital (phone or online) platform meant to help people manage gestational diabetes during pregnancy. If you qualify, you may be asked to use the tool to support daily self-care and decision-making.
LinköpingAges 18–50 - NCT05316493RecruitingPhase 2/Phase 3
Weight-loss and progesterone treatments for early uterine lining disease
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
ShanghaiAges 18–45 - NCT05354947Recruiting
Ultrasound test in adults with type 2 diabetes
This study tests whether a series of ultrasound treatments can improve blood sugar control in people with type 2 diabetes. You may be asked to stay on your current diabetes pills and avoid certain other medicines during the study.
New Haven, ConnecticutAges 21–75 - NCT05355272RecruitingPhase 2
Growth hormone treatment for Gulf War illness with low growth hormone
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
Houston, TexasAges 18–64 - NCT05320796RecruitingPhase 4
Esomeprazole study after gastric bypass and pouch acid levels
This trial tests how well esomeprazole (a acid-reducing medicine) works after a Roux-en-Y gastric bypass, and how it changes the acidity in the stomach pouch. It may help confirm the best way to control stomach acid after bypass surgery.
Schlieren, SchlierenAges 18 years+ - NCT05359562Recruiting
Hormones and OCD treatment approach on the brain
This study looks at how hormone changes and a specific OCD therapy method affect brain activity. It may help researchers understand why OCD symptoms and brain patterns differ between people and across time.
New York, New YorkAges 18–45 - NCT05318196Recruiting
Predict kidney disease risk and progression from patient data
This trial looks at ways to predict how kidney disease may develop, change, or cause complications using information from patients. It may help doctors identify people at higher risk and tailor care earlier.
ToulouseAges 18–99 - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05356117Recruiting
Exercise plus protein shakes for people with pancreatic cancer
This trial studies whether a supervised resistance exercise program combined with protein supplementation can help people with non-metastatic pancreatic cancer during chemotherapy. It may improve strength and how well you tolerate treatment, with safety monitoring throughout.
Boston, MassachusettsAges 18 years+ - NCT05335811RecruitingPhase 1
PET scan test of a new radioactive drug for tumors and inflammation
This Phase 1 study tests whether a new PET imaging tracer (a small amount of radioactive medicine) is safe and how it moves through the body. It’s mainly for adults with cancer who have signs of inflammation or possible immune side effects, so doctors can see what’s happening in the body.
Houston, TexasAges 18 years+ - NCT05326750Recruiting
Brain stimulation to help diagnose and manage memory conditions
This trial studies a non-invasive brain-stimulation approach to help doctors assess and manage certain brain-related conditions. You might benefit by contributing to better diagnostic tools and treatment planning for memory and thinking problems.
KuopioAges 18 years+ - NCT05325736Recruiting
Study how bariatric surgery changes blood sugar response
This study looks at how blood sugar responds after bariatric surgery (or related surgery) and whether changes can be measured over time. It may help doctors better understand which people respond best after surgery.
RehovotAges 18–70 - NCT05317455RecruitingEarly Phase 1
Studying brain sugar changes in adults with risky low blood sugar
This early-stage study looks at how the brain uses sugar in people with type 1 diabetes who have had severe or hard-to-notice low blood sugar. It may help researchers understand the brain effects of low blood sugar and guide safer care.
New Haven, ConnecticutAges 18–55 - NCT05348564Recruiting
Family genetic screening methods for heart rhythm risk
This study compares two ways to find relatives who may carry a specific inherited genetic change. It may help your family learn faster who should get follow-up testing and care.
Lancaster, PennsylvaniaAges 18 years+ - NCT05322213RecruitingPhase 1
THC study for blood sugar control in type 2 diabetes
This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.
La Jolla, CaliforniaAges 21–70 - NCT05325034Recruiting
Lipid-lowering plan after heart attack in adults
This study tests a cholesterol-lowering treatment plan for adults admitted for a Type 1 heart attack. It may help your care team choose guideline-based cholesterol goals and treatments after the event.
Wollongong, New South WalesAges 18 years+ - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Anchorage, AlaskaAges 40–75 - NCT05346627Recruiting
Home training with video coaching for mitochondrial muscle disease
This study tests whether personalized home exercise plus video check-ins are safe and helpful for people with mitochondrial myopathy. It aims to improve function and comfort while checking that the program is tolerable over time.
Nice, Alpes MaritimesAges 18 years+ - NCT05346536Recruiting
Test blood test for a specific type of pancreatic cancer cell
This trial looks for pancreatic cancer markers in a blood sample (“liquid biopsy”), focusing on cells that show a certain protein (AXL). It may help doctors detect and better track advanced pancreatic cancer before or during first-line treatment.
MontpellierAges 18 years+ - NCT05326477Recruiting
Study factors that predict how well behavioral weight plans work
This study looks at which personal and health factors help or hurt how well behavioral obesity treatments work. It may help doctors better tailor weight-treatment plans for people with obesity.
Chicago, IllinoisAges 18 years+ - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT05193396RecruitingPhase 4
Hydrocortisone trial for adrenal symptoms after stopping steroid pills
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
AarhusAges 50 years+ - NCT05266976Recruiting
Exercise types and bone markers in healthy older veterans
This study compares different ways of exercising to see how they affect “bone-related” blood markers in older adults. It may help you and researchers understand which exercise patterns support healthy bones.
Aurora, ColoradoAges 60 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,639 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,048 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.