Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,639 recruiting studies in this area right now.
By phase
- Not applicable5,357
- Phase 2608
- Phase 1562
- Phase 3419
- Phase 4318
- Phase 1/Phase 2289
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer112
- Overweight106
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California523
- Maryland178
- Alabama175
- Arizona171
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,639 total
- NCT05370014Recruiting
Partner support program for chronic health conditions
This study tests a program that helps patients with chronic health conditions and their care partners work together to improve their health and well-being. If you live in a rural or underserved area in South Carolina and have a condition like diabetes or high blood pressure, you and your support person might be able to join.
Columbia, South CarolinaAges 18 years+ - NCT05408728Enrolling by invitation
Check how sugar absorption predicts weight loss after endoscopy
This study looks at whether a person’s “sugar absorption” pattern can help predict how much weight they will lose. It involves an endoscopy (a look inside the upper digestive tract) as part of routine care, and then matching the results to future weight change.
Jacksonville, FloridaAges 18 years+ - NCT05410977Recruiting
Testing blood and stool for colon cancer in Lynch syndrome
This study collects blood and stool samples to see how well they can detect colorectal cancer or advanced growths in people with Lynch syndrome (an inherited colon cancer risk) or suspected Lynch syndrome. It may help find cancer or precancer earlier, which can improve next-step decisions.
Scottsdale, ArizonaAges 18 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Huntsville, AlabamaAges 40–80 - NCT05377268Recruiting
Ultrasound scan to find insulin skin lumps and improve sugar control
This study uses an ultrasound scan to find fatty lumps on the skin caused by insulin injections (called lipohypertrophy). It aims to help you improve blood sugar control by identifying and addressing where insulin is being injected.
Vancouver, British ColumbiaAges 19–80 - NCT05403177Recruiting
Share your cancer data and samples for Ontario research
This study collects and combines medical records, genetic (genomic) data, and tumor/blood samples from people with cancer. It helps researchers build and improve a large “gold standard” cancer dataset that can support future studies and better understanding of cancer.
Kingston, OntarioAges 18 years+ - NCT05394363Recruiting
Victoria children birth-cohort study with parent/guardian consent
This study follows children born in a specific 2-year window and their parents or guardians over time. It helps researchers understand how children and families change as they grow, which can guide future health supports in Victoria.
Parkville, VictoriaAges 1 day+ - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05401162Recruiting
Chemo with your own stem cells for ovarian cancer
This study looks at giving chemotherapy with an added support step using your own collected stem cells. It may help people with recurrent or metastatic ovarian cancer by supporting bone marrow recovery while treatment continues.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT05364879Recruiting
Exercise before ovarian cancer surgery
This trial tests whether supervised exercise (before surgery) can help people with advanced ovarian cancer get ready for treatment. It’s meant to improve readiness and safety during the time leading up to surgery.
Halifax, Nova ScotiaAges 18 years+ - NCT05364957Recruiting
Gastric balloon plus asthma care for uncontrolled asthma and obesity
This study tests whether placing a soft “balloon” inside the stomach (intragastric balloon) can help people who have uncontrolled asthma and obesity. It also checks whether the balloon is safe and can improve asthma control when standard inhaler treatment is already in use.
Toulouse, OccitanieAges 18–65 - NCT05370079Recruiting
Control group for people with specific serious illnesses
This trial includes a “control” group of people with certain diseases to compare outcomes against another group. If you qualify, you may receive the standard approach used in usual care rather than the experimental treatment.
BronAges 18 years+ - NCT05411718RecruitingPhase 2
Aspirin or naproxen to prevent cancer in Lynch syndrome
This trial tests whether daily aspirin or naproxen can “intercept” (stop) cancer from starting or coming back in people with Lynch syndrome who are currently cancer-free. Participants are randomly assigned to one of the two drugs, and neither the participant nor the team knows which one you’re taking.
Houston, TexasAges 18 years+ - NCT05368090Recruiting
Ultrasound-guided ablation for primary aldosteronism
This trial studies whether a procedure called endoscopic ultrasound–guided radiofrequency ablation can treat primary aldosteronism (a hormone condition that can raise blood pressure and potassium issues). It may help shrink an overactive adrenal growth and reduce the need for surgery for some people.
BergenAges 18–80 - NCT05388643Recruiting
Early screening for gestational diabetes during early pregnancy
This study tests whether checking for gestational diabetes (diabetes that starts in pregnancy) early can help identify it sooner in people at higher risk. You may be asked to do a glucose test during your first prenatal visits so clinicians can monitor and respond earlier.
Worcester, MassachusettsAges 18 years+ - NCT03369821Recruiting
Study of immune changes in very early childhood type 1 diabetes
This study looks at immune system cells and gene activity in infants and young children to understand what causes type 1 diabetes to start so early. It may help researchers find earlier warning signs and better ways to support families right at diagnosis.
Seattle, WashingtonAges Up to 70 years - NCT05088798RecruitingPhase 2
PET/MRI scan to help plan surgery for hyperinsulinism
This Phase 2 study uses special PET/MRI imaging to better understand a cause of hyperinsulinemic low blood sugar and guide whether surgery may help. It may help doctors choose the safest plan to reduce severe episodes and protect the brain.
St Louis, MissouriAges Any age - NCT05359848Recruiting
Intermittent fasting and plant-based eating during chemotherapy
This pilot study tests whether alternating periods of lower calorie intake, along with a plant-based diet, is safe and feasible for people receiving chemotherapy. If it helps, it could support better comfort and treatment tolerance during cancer therapy.
Buffalo, New YorkAges 18 years+ - NCT05325736Recruiting
Study how bariatric surgery changes blood sugar response
This study looks at how blood sugar responds after bariatric surgery (or related surgery) and whether changes can be measured over time. It may help doctors better understand which people respond best after surgery.
RehovotAges 18–70 - NCT05355272RecruitingPhase 2
Growth hormone treatment for Gulf War illness with low growth hormone
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
Houston, TexasAges 18–64 - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05336760Recruiting
ALS study of swallowing comfort, quality of life, and PEG views
This study looks at swallowing problems in people with ALS and how they affect quality of life, including people’s attitudes toward PEG (a feeding tube). It may help researchers understand what support and information could improve comfort and day-to-day living.
LjubljanaAges 18 years+ - NCT05348863Recruiting
Digital coaching for self-care in gestational diabetes
This trial studies a digital (phone or online) platform meant to help people manage gestational diabetes during pregnancy. If you qualify, you may be asked to use the tool to support daily self-care and decision-making.
LinköpingAges 18–50 - NCT05346627Recruiting
Home training with video coaching for mitochondrial muscle disease
This study tests whether personalized home exercise plus video check-ins are safe and helpful for people with mitochondrial myopathy. It aims to improve function and comfort while checking that the program is tolerable over time.
Nice, Alpes MaritimesAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,639 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,048 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.