Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07790744Recruiting
Brain imaging study for early Parkinson's signs in people with REM sleep disorder
This study uses MRI scans to look at the brain in people with REM sleep behavior disorder (RBD), a condition that can be an early sign of Parkinson's disease. By comparing them with healthy volunteers, researchers hope to find early markers of Parkinson's that could lead to earlier diagnosis and treatment.
HvidovreAges 18 years+ - NCT07789847Recruiting
How water intake affects thinking
This study looks at how your usual water intake affects your thinking and memory. You'll need to be a healthy adult, and they'll check your hydration levels before you join.
LiverpoolAges 18–35 - NCT03240653Recruiting
Study to sort people with Gaucher disease into groups
This study looks at people with Gaucher disease (types I, II, or III) to better “group” patients for understanding and future research. If you (or your child) have confirmed Gaucher disease, you may be asked to share information and follow a study schedule.
BirminghamAges Any age - NCT07785934RecruitingPhase 1
Testing a new weight management injection for drug interactions
This study tests a new injectable medication for weight management in people with overweight or obesity. It investigates how the drug interacts with other medications and checks its safety. Participation requires a 6-month commitment with regular study visits.
Hefei, AnhuiAges 18–45 - NCT07784374RecruitingPhase 2
Study of new targeted therapies for advanced pancreatic cancer
This trial tests three new targeted drug combinations for pancreatic cancer that has a specific genetic change (KRAS G12D). They are comparing the study drug alone versus combining it with other investigational drugs to see which works better.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07784699RecruitingPhase 1
Testing an experimental pill for weight loss in healthy or overweight adults
This study tests an experimental pill (GZC8072) for weight loss. It is a phase 1 trial, meaning it is one of the first times the drug is given to people, and the focus is on safety and how the body handles it. You would receive either a single dose (if you are healthy) or multiple doses (if you are overweight or obese) to see how the medication works.
BeijingAges 18–55 - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Fairhope, AlabamaAges 18 years+ - NCT07789223Recruiting
Weight management study with natural supplements
This study tests a natural supplement (elénzia CONTROL®) to help with weight loss and metabolic health. Researchers want to see if it works for people who have never used GLP-1 medications or who have stopped using them.
Redditch, West MidlandsAges 25–65 - NCT07790562RecruitingPhase 1
Study of an iron injection for people with iron deficiency anemia
This study tests an iron injection for treating iron deficiency anemia. It checks how the medicine works in the body, and may help people whose blood iron is too low.
ZhengzhouAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Dothan, AlabamaAges 18 years+ - NCT06532461Recruiting
Comparing 3 vs 7 day insulin pump wear in teens with type 1 diabetes
This study tests if wearing an insulin pump set for 7 days is as safe and effective as changing it every 3 days. It is for children and teens with type 1 diabetes who already use the Medtronic 780G system.
Herlev, CapitalAges 7–18 - NCT06540690Recruiting
Healing after gum graft surgery: diabetic vs non-diabetic
This study looks at how well the roof of the mouth heals after a small piece is taken for a gum graft. It compares healing in people with type 2 diabetes to healing in people without diabetes. The goal is to see if diabetes affects recovery.
São José dos Campos, São PauloAges 18–80 - NCT06219759Recruiting
Nerve Reconnection and Signals in ALS
This study looks at how nerves reconnect and send signals to muscles in people with ALS. It may help doctors understand the disease better and find new ways to treat it.
Aarhus, Central JutlandAges 18 years+ - NCT06542822Recruiting
IV iron for non-ischemic heart failure with low iron
This study tests whether intravenous iron can improve outcomes for people with non-ischemic heart failure and low ejection fraction who are also iron deficient. If you fit the criteria, you may receive iron infusions to see if it helps your heart function and symptoms.
Southampton, HampshireAges 18 years+ - NCT06541340Recruiting
Drainage before surgery for pancreatic cancer with jaundice
This study tests a specific drainage step before surgery for patients with pancreatic head cancer who have severe jaundice. It aims to see if this approach improves outcomes compared to standard care.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06394492RecruitingPhase 3
Testing a new drug for platinum-resistant ovarian cancer
This study tests a new drug called SHR-A1921 for people with ovarian cancer that no longer responds to platinum chemotherapy. The goal is to see if it can shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05837260Recruiting
Tracking tumor DNA changes in advanced thyroid cancers
This study looks at a small blood test (called ctDNA) and tumor tissue to understand how advanced thyroid cancers change over time. It may help doctors better monitor cancer growth and guide treatment choices.
LondonAges 18 years+ - NCT06545227Recruiting
Early vs. Late Monitoring for Gestational Diabetes History
This study looks at whether checking blood sugar levels earlier or later in pregnancy is better for women who had gestational diabetes before. It aims to find the best time to start monitoring to help protect both mom and baby.
LondonAges 17–45 - NCT06544876Recruiting
Balance and recovery in diabetes nerve damage
This study looks at how diabetes-related nerve damage affects balance and the ability to recover from a stumble. It may help find better ways to prevent falls.
Austin, TexasAges 50–99 - NCT07776509RecruitingPhase 3
Adding a new drug to current weight-loss therapy for adults with obesity or overweight
This study tests a new medication (AZD6234) added to your current weight-management medication (an incretin-based drug) to see if it helps with weight loss. You may be eligible if you are overweight or obese with related health issues or type 2 diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07783087Recruiting
Wound gel for diabetic foot ulcers
This study tests whether a new wound gel helps heal diabetic foot ulcers better than the standard gel. It is for people with mild to moderate foot ulcers who have good blood flow and are not taking certain medications.
Bonheiden, AntwerpAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT07776691RecruitingPhase 3
Study of Raludotatug Deruxtecan for Advanced Ovarian Cancer
This study tests a new drug (raludotatug deruxtecan) with or without another drug (bevacizumab) as maintenance therapy after initial chemotherapy for advanced ovarian cancer. It aims to see if this combination can help keep the cancer from coming back.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07776626RecruitingPhase 1
Study of YOLT-203 for Primary Hyperoxaluria Type 1
This study tests a new treatment for primary hyperoxaluria type 1, a rare condition that causes too much oxalate in the body, which can lead to kidney stones and kidney damage. The treatment is given as an injection, and the study will see if it is safe and how the body responds.
Shanghai, Shanghai MunicipalityAges 6 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.