Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT07708064Recruiting
Preventing weight regain with a smartphone program
This study tests a smartphone-based program to help people who have lost weight keep it off or lose more. It uses personalized tips and check-ins to prevent giving up if you regain some weight.
Springfield, OregonAges 18–70 - NCT07714538Recruiting
Breath test for detecting gastrointestinal cancers
This study tests whether a simple breath test can help detect different types of gastrointestinal cancers earlier. If you have been recently diagnosed with one of these cancers or have concerning abdominal symptoms but clear test results, your breath may help teach us how to spot these cancers sooner.
Maidstone, KentAges 18 years+ - NCT07707830Recruiting
Thyroid and body health assessment for adults with low thyroid function
This study looks at how an underactive thyroid (hypothyroidism) affects internal organs, muscles, and bones. It uses ultrasound and physical measurements to understand these effects, which may help improve care.
AndijanAges 18–59 - NCT07711925Enrolling by invitation
MRI body changes before and after weight loss surgery
This study uses MRI scans to measure how your body composition changes after bariatric surgery. If you are planning weight loss surgery, you may help doctors understand what happens to your body fat and muscle over time.
Olsztyn, Warminsko-mazusrkieAges 18 years+ - NCT07712900Recruiting
Nutrition counseling for diabetes and high blood pressure
This trial tests whether nutrition counseling helps people who have both type 2 diabetes and high blood pressure. It aims to improve their heart and metabolic health.
DessieAges 18 years+ - NCT07710274Recruiting
Personalized Program for Insulin Resistance in Metabolic Syndrome
This pilot study tests a personalized program called PRISM to help improve how your body responds to insulin. If you have metabolic syndrome (a cluster of conditions like large waist size, high blood pressure, or high blood sugar) and insulin resistance, the study will use a continuous glucose monitor, smart ring, and food logging app to give you tailored feedback.
SingaporeAges 21–70 - NCT07711171RecruitingPhase 4
Canagliflozin for type 2 diabetes with mild memory problems
This trial tests whether the diabetes drug canagliflozin can help people with type 2 diabetes and mild cognitive impairment. It may slow down memory and thinking problems while also improving blood sugar control.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT07707401Recruiting
WeChat neck exercises for recovery after thyroid surgery
This study tests whether simple neck exercises, guided through the WeChat app, can help you recover more quickly after thyroid surgery. If you have no serious complications and don't have neck problems, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07713030Recruiting
Exercise types for prediabetes: high-intensity vs. steady
This study compares two exercise programs (short bursts of intense activity vs. longer, steady exercise) to see which works better for people with prediabetes. It may help you prevent or manage diabetes through a structured fitness routine.
Lahore, Punjab ProvinceAges 35–54 - NCT07707531RecruitingEarly Phase 1
Trial of radioactive drug for gastric and pancreatic cancer
This study tests a radioactive drug that targets a protein called Claudin 18.2 found on some stomach and pancreatic cancer cells. Researchers will track where the drug goes in your body and how it exits, to see if it's a safe and effective way to deliver radiation directly to tumors.
ShanghaiAges 18 years+ - NCT06640348Recruiting
New blood test for ovarian cancer screening
This study uses a special blood test (SERS) to find tiny signs of ovarian cancer in the blood. It may help diagnose ovarian cancer earlier or more accurately.
Hefei, AnhuiAges 18–70 - NCT04834518Recruiting
Screening children for early signs of type 1 diabetes
This study checks for specific blood markers (“islet autoantibodies”) to find children who may be at risk for developing type 1 diabetes later, before symptoms start. It’s mainly for children who have no known diabetes yet.
BeershebaAges 9 months–5 years - NCT06642363RecruitingPhase 1
Astaxanthin for PCOS symptoms and heart health
This trial tests if astaxanthin, a natural antioxidant, can improve PCOS symptoms and heart-related health in women with PCOS who are overweight but not pregnant or breastfeeding.
Isfahan, IsfahanAges 18–45 - NCT06538831Recruiting
Ultra-processed foods and heart health
This study looks at how eating ultra-processed foods (like packaged snacks and sugary drinks) affects heart health markers such as cholesterol and blood pressure. If you are generally healthy and have a stable weight, you may be able to join.
Québec, QuebecAges 18–75 - NCT07701590Recruiting
New wound dressings for hard-to-heal leg and foot ulcers
This study tests a special amniotic membrane wound dressing compared to a synthetic wound matrix for stubborn diabetic foot ulcers or venous leg ulcers. It may help if your wound has not been healing well for over a month.
San Diego, CaliforniaAges 18 years+ - NCT07705607RecruitingPhase 3
Comparing MK-8748 to standard treatment for diabetic eye swelling
This trial tests a new medicine (MK-8748) against an existing treatment (aflibercept) for people with diabetic macular edema, which causes vision loss due to swelling in the back of the eye. The goal is to see which works better to improve or protect vision.
Winter Haven, FloridaAges 18 years+ - NCT07705191Recruiting
Peanut skin extract for blood sugar control
This trial studies whether an peanut skin extract can help control blood sugar after a meal. It is looking for healthy adults who do not have diabetes.
TainanAges 18 years+ - NCT07699471RecruitingPhase 3
Study of a new drug for adults with low parathyroid hormone
This trial tests an experimental drug called Canvuparatide against a placebo to see if it can help adults with a condition called hypoparathyroidism, where the body doesn't make enough parathyroid hormone. The goal is to improve calcium levels and reduce the need for high-dose calcium and vitamin D supplements.
Englewood, ColoradoAges 18 years+ - NCT07702292RecruitingPhase 2
68Ga-BED003 PET scan for certain cancers
This trial tests a new PET imaging agent that targets a protein called FAP, which appears in many solid tumors. The goal is to see if this scan can better find and measure cancer in the body.
Bergamo, LombardyAges 18–79 - NCT07705555RecruitingPhase 3
Comparing a new eye injection to standard treatment for diabetic eye swelling
This trial tests if a new medicine (MK-8748) works as well as or better than the usual treatment (aflibercept) for people with diabetic macular edema, a condition that causes vision loss from diabetes-related swelling in the back of the eye.
Glendale, CaliforniaAges 18 years+ - NCT07702890RecruitingPhase 1/Phase 2
Testing a new drug for obesity and type 2 diabetes
This trial tests an investigational drug called GUB-UCN2 in people who are healthy, overweight, or have type 2 diabetes. The goal is to see if the drug is safe and how the body processes it.
NeussAges 18–75 - NCT07704658RecruitingPhase 4
Pralsetinib drug interaction study for advanced solid tumors
This trial tests how pralsetinib interacts with other drugs in people with advanced solid tumors that have a specific RET gene change. It aims to find the right dose and safety profile.
Logroño, La RiojaAges 18 years+ - NCT07701486RecruitingPhase 1/Phase 2
Testing more frequent VCN-01 with standard chemo for new pancreatic cancer
This study tests a more frequent schedule of the experimental drug VCN-01 along with standard chemotherapy (nab-paclitaxel and gemcitabine) for people newly diagnosed with pancreatic cancer that has spread. The goal is to see if the virus-based therapy can help shrink tumors better.
Madrid, MadridAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.