Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07718217Recruiting
Mindfulness education for women with PCOS
This study tests whether a 4-week online mindfulness program can help women with PCOS manage stress and improve well-being. You'll attend group sessions and complete surveys from home.
BursaAges 18–49 - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT06635590Recruiting
Kidney disease, high potassium, and heart changes
This study looks at how high potassium levels (hyperkalemia) in people with chronic kidney disease may affect the heart. Doctors will use echocardiograms (heart ultrasounds) to check for changes.
AnkaraAges 18 years+ - NCT04427189Recruiting
Diabetes registry for children and teens with better care
This study builds a diabetes “registry” to better understand how diabetes is managed in children and teens. Your information helps create reference centers and improve care, and you must be willing to follow study instructions.
Hanover, Low SaxonyAges Any age - NCT05277532Recruiting
Exercise and sleep timing for overweight type 1 diabetes
This trial studies whether changing daily sleep timing (circadian rhythm) and doing physical exercise can improve health outcomes in people who are overweight and have type 1 diabetes (or in some healthy people). It may help by seeing what combinations of routine and activity are most beneficial.
StockholmAges 18–50 - NCT05462496RecruitingPhase 2
Pembrolizumab plus gut microbiome changes after pancreatic chemo
This Phase 2 study tests whether changing the gut microbiome (the gut’s helpful bacteria) and giving pembrolizumab after chemotherapy can improve outcomes for people with operable pancreatic cancer. It aims to see if this approach can boost the immune system after standard treatment and help reduce cancer returning.
New York, New YorkAges 19 years+ - NCT05990491Recruiting
Pituitary function after recovery from septic shock in ICU survivors
This study checks how well the pituitary gland (a small gland in your brain that controls hormones) works after you recover from a severe infection that caused dangerously low blood pressure (septic shock). It aims to see if the gland was affected during your ICU stay.
Lucknow, Uttar PradeshAges 18–80 - NCT05894746Recruiting
Study to improve blood sugar and reduce inflammation
This study looks at how an intervention may improve blood sugar control and lower inflammation in the body. You may be able to take part unless you have a specific condition called celiac disease.
GothenburgAges 6 years+ - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06638593Recruiting
Comparing open vs. robotic surgery for pelvic masses up to 8cm
This study compares two types of minimally invasive surgery—traditional laparoscopic (keyhole) versus robotic-assisted—for removing complex ovarian cysts or masses up to 8cm that haven't spread. The goal is to see which approach might offer better recovery and outcomes for women with these growths.
GuildfordAges 18–100 - NCT06638424Recruiting
Cataract surgery effects on eyes in diabetic patients
This study looks at how cataract surgery affects the surface of the eye in people with diabetes. Researchers want to see if the surgery causes changes, so they can better understand and care for diabetic patients.
StrasbourgAges 18 years+ - NCT06642831Recruiting
PCOS biomarker study for young women
This study looks for biological markers of polycystic ovary syndrome (PCOS) in young women. If you are between 15 and 25 and have not used hormonal birth control recently, you may be able to help researchers find better ways to diagnose PCOS.
ErlangenAges 15–25 - NCT07714668RecruitingPhase 2
Combination therapy for recurrent ovarian cancer
This study tests a new combination treatment for ovarian cancer that has come back after earlier treatment. It aims to see if the combination can shrink tumors or slow the disease, and it may be an option for people whose cancer has become resistant to platinum-based chemotherapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07706764RecruitingPhase 3
Testing a new treatment for teens with long-term hypoparathyroidism
This study tests a new medicine called palopegteriparatide for teenagers with long-term hypoparathyroidism (low parathyroid hormone). The medicine is given as a daily injection and aims to help control calcium levels.
BronAges 12–18 - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07713758RecruitingPhase 1
How the body handles repinatrabit with liver or kidney issues
This trial checks how repinatrabit is processed in people with moderate liver problems or severe kidney problems compared to healthy adults. It helps doctors understand if the dose should be adjusted for these conditions.
Miami, FloridaAges 18–65 - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07710430RecruitingPhase 4
Leuprorelin for children with central precocious puberty
This study tests a monthly injection of leuprorelin to see if it can slow or stop early puberty in children with central precocious puberty. It may help children who start puberty too early grow at a more typical pace.
SeoulAges Up to 10 years - NCT07710729RecruitingPhase 1
How UBT251 Affects Birth Control and Stomach Emptying
This study tests a new medicine, UBT251, to see if it affects how birth control pills work and how quickly food leaves the stomach. It is for women with overweight or obesity who cannot get pregnant.
Montreal, QuebecAges 18–65 - NCT06642623RecruitingPhase 4
Study on heart and kidney health in type 2 diabetes
This trial tests enavogliflozin (a newer SGLT2 inhibitor) compared to older drugs (dapagliflozin or empagliflozin) to see how well it protects the heart and kidneys in people with type 2 diabetes.
SeoulAges 19 years+ - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT07712900Recruiting
Nutrition counseling for diabetes and high blood pressure
This trial tests whether nutrition counseling helps people who have both type 2 diabetes and high blood pressure. It aims to improve their heart and metabolic health.
DessieAges 18 years+ - NCT07710274Recruiting
Personalized Program for Insulin Resistance in Metabolic Syndrome
This pilot study tests a personalized program called PRISM to help improve how your body responds to insulin. If you have metabolic syndrome (a cluster of conditions like large waist size, high blood pressure, or high blood sugar) and insulin resistance, the study will use a continuous glucose monitor, smart ring, and food logging app to give you tailored feedback.
SingaporeAges 21–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.