Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT06723886Recruiting
Can olive pomace oil help control blood sugar?
This study tests whether olive pomace oil, a type of olive oil, can lower blood sugar in people with prediabetes or diabetes. It may be an option if you have high blood sugar and are not taking other medications or supplements.
Madrid, MadridAges 20–70 - NCT06729203Recruiting
Ultrasound for belly fat and insulin resistance in women
This trial tests if ultrasound cavitation—a non-invasive treatment that uses sound waves to break down fat—can help lower insulin resistance in women with central obesity (fat around the belly). It's a possible option if you have insulin resistance and are not taking diabetes medication.
Giza, Giza GovernorateAges 25–40 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT03441451Recruiting
Bariatric Surgery Registry for people with high BMI
This registry collects information from people who have a higher body weight (BMI over 30). It may help researchers better understand bariatric surgery and outcomes for future care.
Melbourne, VictoriaAges 2–95 - NCT05668962RecruitingPhase 2
Study selpercatinib plus I-131 for RET thyroid cancer that cannot take iodine
This trial tests whether combining a targeted pill (selpercatinib) with a radioactive iodine dose (I-131) can shrink thyroid cancer that has spread and no longer responds to radioactive iodine. It is for RET fusion–positive (genetically driven) thyroid cancers where the cancer cannot reliably absorb iodine anymore.
Washington D.C., District of ColumbiaAges 12 years+ - NCT06126016Recruiting
A study of Pacitol Inj. for dialysis patients with parathyroid issues
This study watches how well the drug Pacitol Inj. works and how safe it is in people on dialysis who have overactive parathyroid glands caused by kidney disease. It follows patients who are already prescribed this drug by their doctor.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06655701Recruiting
Bladder leaks and muscle loss in postmenopausal women with bone thinning
This study looks at whether women with osteoporosis (thin bones) after menopause also have bladder leaks and loss of muscle mass. It may help understand links between these conditions.
IstanbulAges 50–75 - NCT06730529Recruiting
Using 68Ga-FAPI PET/CT scan for thyroid cancer lymph nodes
This study uses a special type of PET/CT scan (68Ga-FAPI) to see how well it finds cancer spread in lymph nodes before thyroid cancer surgery. It may help doctors plan your treatment more accurately.
Shanghai, Shanghai MunicipalityAges 16–80 - NCT04113122Recruiting
Study of early aging after chemotherapy in young testicular cancer patients
This study looks at how chemotherapy may affect “early aging” in people who had metastatic testicular cancer before age 50. It includes people who are starting cisplatin-based chemotherapy and a comparison group with earlier-stage disease.
GroningenAges 18–50 - NCT06647550RecruitingPhase 2
Testing a new pill for type 2 diabetes not well controlled by diet and exercise
This trial tests a new medication, HD-6277, to see if it can help lower blood sugar in adults with type 2 diabetes that isn't well managed by diet and exercise alone.
SeoulAges 19–75 - NCT06141811Recruiting
Long-term safety study for diabetic foot ulcer treatment
This study follows up on patients who received an experimental cell sheet (ALLO-ASC-DFU) or a placebo in a previous trial. It checks for any new safety concerns over time.
Bucheon-si, Gyeonggi-doAges 19–75 - NCT06700915Recruiting
Berberine supplement study for blood sugar support
This study tests if a berberine-based supplement can help regulate blood sugar and metabolism in people who are overweight and have slightly elevated blood sugar (prediabetes). Participants will take the supplement and maintain their normal lifestyle.
Santa Monica, CaliforniaAges 18–70 - NCT07560956Enrolling by invitation
Quality of Life in Adults With Untreated Fabry Disease
This study looks at how Fabry disease affects daily life in adults who haven't started treatment yet. Researchers want to understand your experiences and challenges to improve care for people with this rare genetic condition.
GothenburgAges 18 years+ - NCT06710067Recruiting
Urine chemicals for diagnosing disease
This study looks at chemicals in urine to help find new ways to diagnose diseases. You give one urine sample and answer a few questions—no treatment or long-term follow-up needed.
Encinitas, CaliforniaAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Birmingham, AlabamaAges 18 years+ - NCT07565064Enrolling by invitation
Vitamin D Blood Test Stability Study
This study tests how accurately a vitamin D blood test works with fresh versus frozen samples. Your blood samples will help researchers understand the best way to store and measure vitamin D levels.
Salem, New HampshireAges 22 years+ - NCT07565506RecruitingPhase 2
Nu-3 Gel for Mild Diabetic Foot Infections
This study tests a new gel treatment (Nu-3) for mild infections in diabetic foot ulcers. The goal is to find the right dose and see if it helps heal these wounds safely.
Los Angeles, CaliforniaAges 18 years+ - NCT07567131Recruiting
Understanding sun sensitivity in rare porphyria disorders
This study tracks how your body reacts to sunlight if you have erythropoietic protoporphyria (EPP) or X-linked protoporphyria (XLP)—rare genetic conditions that cause painful skin reactions to sun exposure. Researchers will use special devices and daily logs to better understand your symptoms and how light affects your skin.
Boston, MassachusettsAges 12 years+ - NCT07566390RecruitingPhase 1
Testing a new weight-loss medicine in healthy adults
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Glendale, CaliforniaAges 18–55 - NCT07563738RecruitingPhase 1/Phase 2
ODM-212 with cancer immunotherapy for advanced solid tumors
This trial tests a new drug called ODM-212 combined with existing cancer treatments for mesothelioma, pancreatic cancer, or lung cancer with a specific genetic mutation. The study aims to find the right dose and see if adding ODM-212 helps these treatments work better.
Irving, TexasAges 18 years+ - NCT07563699RecruitingPhase 1/Phase 2
Long-acting semaglutide injection for type 2 diabetes
This study tests a new long-acting form of semaglutide (a diabetes medication you may already take weekly) given as a depot injection. Researchers want to see if this new form is safe and works better for managing type 2 diabetes.
Tel AvivAges 18–64 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07564141RecruitingPhase 3
New Drug for Recurrent Ovarian Cancer After Chemotherapy
This study tests a new medicine called Rina-S (with or without a blood vessel-blocking drug) compared to standard chemotherapy options for ovarian cancer that has come back after initial treatment. The goal is to see if Rina-S works better and is safer than current standard care.
Duarte, CaliforniaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.