Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+ - NCT07512427RecruitingPhase 1/Phase 2
Testing OPK-88006 for Fatty Liver Disease
This trial tests a new experimental drug called OPK-88006 to see if it can help treat MASH, a serious liver condition linked to excess fat buildup. The study has two parts: one with healthy volunteers to check safety, and one with people who have signs of fatty liver disease.
Miami, FloridaAges 18–75 - NCT07511205RecruitingPhase 1
Study of AZD1043 for overweight or obesity
This trial tests a new medicine called AZD1043 in healthy adults who are overweight or have obesity. It aims to see if the medicine is safe and how the body handles it.
Glendale, CaliforniaAges 18–65 - NCT07514338RecruitingPhase 2
Long-term safety study of KL1333 for mitochondrial disease
This is a follow-up study for patients who completed a previous trial (FALCON) testing KL1333, an experimental medicine for primary mitochondrial disease—a condition where cells don't produce enough energy. The study tracks how safe and effective the treatment remains over time.
Akron, OhioAges 18 years+ - NCT07508020RecruitingPhase 1
How a new medicine affects appetite and metabolism in people with obesity
This study tests an experimental drug (NNC0487-0111) to see how it changes food intake, appetite, and the way your body processes food after meals. It is for adults with obesity who do not have diabetes.
BerlinAges 18–64 - NCT07510347Recruiting
Pain relief study for sleeve gastrectomy patients
This study tests if giving pain medicine in a different area of the abdomen can reduce pain after weight-loss surgery. It may help you feel more comfortable after your sleeve gastrectomy.
Shibīn al Kawm, MenofiaAges 20–60 - NCT07508553Recruiting
Bone density in third trimester: singleton vs. twin pregnancy
This study compares bone density in the third trimester between women pregnant with one baby versus twins. If you qualify, you'll fill out questionnaires and have a quick, non-invasive bone scan to help researchers understand how pregnancy affects bone health.
Roma, RMAges 30–45 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07511283Recruiting
Calciphylaxis study in kidney disease patients
This study looks at a rare condition called calciphylaxis (hardening of small blood vessels) that can happen in people with chronic kidney disease. It aims to learn more about what causes it and how to help those affected.
OdenseAges 18 years+ - NCT07515391Enrolling by invitationPhase 2
Blood Sugar Control After Weight-Loss Surgery
This trial tests whether a diabetes medication called dapagliflozin helps smooth out blood sugar swings after bariatric (weight-loss) surgery. It may help people with type 2 diabetes achieve better control after their surgery.
Kuwait City, DasmanAges 21–70 - NCT07514663Recruiting
Effects of Corn and Avocado Oils on Heart Health
This study compares how corn oil and avocado oil affect your cholesterol and heart health markers. You'll eat controlled meals containing one of these oils for 3 weeks at a time to see which might be better for your cardiovascular risk factors.
Addison, IllinoisAges 18–74 - NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65 - NCT07508930Recruiting
Russian extreme high triglycerides registry
This study creates a registry for people with very high triglycerides (≥10 mmol/L). It aims to understand who gets this condition and how it affects them over time.
AstrakhanAges Any age - NCT07508631Recruiting
Friedreich Ataxia Nerve Ultrasound Study
This trial uses an ultrasound to look at nerves in people with Friedreich's Ataxia. It may help doctors better understand how the condition affects the nervous system.
Nice, Alpes MaritimesAges 18–70 - NCT07512609Recruiting
How Environment and Inflammation Affect Metabolic Health
This study explores how environmental factors and inflammation in your body might contribute to metabolic diseases like diabetes and heart disease. Researchers will analyze health data from people who've had physical exams to find patterns that could help prevent or manage these conditions.
ChongqingAges Any age - NCT07515547Recruiting
How Obesity Affects the Body Over Time
This research study examines how excess weight impacts your body's health and function, both in the short term and long term. Researchers want to understand the physical changes that happen with obesity and how your body responds.
Montreal, QuebecAges 25–40 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT07512934Recruiting
Pancreatic Function Study in Early Type 2 Diabetes
This study examines how the pancreas works in people newly diagnosed with type 2 diabetes. Researchers will assess pancreatic function to better understand early diabetes and potentially improve treatment.
Aktobe, AktobeAges 18–74 - NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT07507708Recruiting
Smart insulin system with behavior support for type 1 diabetes
This study tests a smart insulin pump and continuous glucose monitor system that adjusts insulin automatically and uses behavior support to improve blood sugar control. It's for people with type 1 diabetes who have used an approved automated insulin delivery system recently and are willing to use study devices.
Charlottesville, VirginiaAges 18 years+ - NCT07509671Recruiting
Can a diet help painful diabetic nerve pain?
This study tests whether a special diet can help reduce pain caused by nerve damage from Type 2 diabetes or prediabetes. You may qualify if you have painful diabetic neuropathy and are looking for a non-medication approach.
Hendersonville, North CarolinaAges 18 years+ - NCT07512804Recruiting
Understanding diabetes after kidney transplant
This study helps doctors predict who may develop complications from diabetes that appears after a kidney transplant. By understanding your individual risk, your care team can better prevent problems and keep your transplanted kidney healthy longer.
RomaAges 18–70 - NCT07513116Recruiting
Intermittent fasting for people at high risk of pancreatic cancer
This study tests whether following an intermittent fasting schedule (eating only during certain hours) can help people at high risk for pancreatic cancer. The trial uses an app to track eating patterns and fasting times, aiming to see if this approach may reduce cancer risk.
Houston, TexasAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.