Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT03087032RecruitingPhase 4
Liraglutide injections vs insulin for uncontrolled type 2 diabetes
This trial compares two treatment approaches—liraglutide injections versus a specific insulin (glargine) injection—plus meal-time insulin dosing (“bolus”) in adults with overweight/obesity and type 2 diabetes that isn’t well controlled. The goal is to see which option works better and is safer for improving blood sugar.
Xiamen, FujianAges 18–75 - NCT06694935RecruitingPhase 1
Testing QX1206 in type 2 diabetes with fatty liver
This trial tests a new pill called QX1206 for people who have both Type 2 diabetes and fatty liver disease (NAFLD). The goal is to see if the medicine is safe and can help improve both conditions.
TorontoAges 18–64 - NCT06641154RecruitingPhase 1/Phase 2
Gene therapy for severe Crigler-Najjar syndrome
This trial tests a gene therapy for children with severe Crigler-Najjar syndrome type I. It aims to reduce the need for daily phototherapy by fixing the faulty gene.
MoscowAges 3 months–10 years - NCT06770621Recruiting
Glucagon response study in new type 1 diabetes
This study looks at how the body makes glucagon (a hormone that raises blood sugar) in children and teens with new type 1 diabetes. It aims to understand why some people may have dangerous low blood sugars, so doctors can better prevent them in the future.
Brussels, Woluwe-saint-lambertAges 2–30 - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT06679816RecruitingPhase 4
Hydrocortisone for hormone replacement in large pituitary tumor surgery
This trial tests hydrocortisone as hormone replacement therapy after surgery for large pituitary tumors. It aims to help patients maintain healthy cortisol levels during recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06773650Recruiting
Managing lactose intolerance with diet and enzyme supplements
This trial tests whether diet tracking and lactase enzyme supplements help people with lactose intolerance manage their symptoms. It uses an online survey to gather information.
MilanAges 18 years+ - NCT07489209RecruitingPhase 2
Study of EDP167 for homozygous familial hypercholesterolemia
This trial tests a new drug, EDP167, for people with homozygous familial hypercholesterolemia (HoFH), a genetic condition that causes very high cholesterol. The goal is to see if EDP167 can lower 'bad' cholesterol (LDL-C).
BeijingAges 18 years+ - NCT07480928RecruitingPhase 1/Phase 2
CAR-NK cell therapy for advanced pancreatic cancer
This trial tests a new type of immune cell therapy called CAR-NK cells that target two proteins (MSLN and MUC1) often found on pancreatic cancer cells. It is for people whose cancer has spread or cannot be removed, and who have already tried at least one standard treatment.
Shenzhen, GuangdongAges 18–75 - NCT07488585Recruiting
New ultrasound probe for thyroid imaging
This trial tests a new ultrasound probe designed to take better images of thyroid nodules. It may help improve the monitoring of nodules over time.
Dartmouth, Nova ScotiaAges 18 years+ - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT07480954RecruitingPhase 1/Phase 2
CAR-NK cell therapy for recurrent ovarian cancer
This trial tests a new type of immune cell therapy (CAR-NK cells) that targets two proteins often found on ovarian cancer cells. It is for people whose cancer has come back after at least two prior treatments.
Shenzhen, GuangdongAges 18–75 - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07489482RecruitingPhase 1
Comparing SHR-3167 injection bioavailability and safety
This trial tests how a new medicine (SHR-3167) is absorbed by the body and checks for side effects. Healthy volunteers ages 18-55 can join to help researchers understand how this drug works.
Changsha, HunanAges 18–55 - NCT07481383RecruitingPhase 1
Implant device for chemo delivery in advanced pancreatic cancer
This trial tests an implantable device that delivers chemotherapy (gemcitabine) directly to pancreatic tumors. It may offer a new treatment option for people with non-metastatic, advanced pancreatic cancer that cannot be surgically removed.
Ann Arbor, MichiganAges 18 years+ - NCT06582914Recruiting
Lynch syndrome genetics and health study
This study looks at the genetics and health of people with Lynch syndrome, a condition that raises the risk for certain cancers. Researchers want to learn more about how different genetic changes affect health over time.
Aurora, ColoradoAges 18 years+ - NCT07481305Recruiting
Digital lifestyle program for people starting glp-1 medication
This study is testing whether a 4-month digital lifestyle program (with a Fitbit) can help people who recently started taking a GLP-1 medication make healthier habits and lose more weight. You would use an app or website to get support and track your progress.
Worcester, MassachusettsAges 18 years+ - NCT07488767Enrolling by invitation
Food order study for diabetes with food insecurity
This study looks at whether changing the order you eat your food (like vegetables first, then carbs) can help people with prediabetes or diabetes who also experience food insecurity. It aims to find simple, low-cost ways to improve blood sugar control.
New York, New YorkAges 18–75 - NCT07483879Recruiting
Organ Injury Biomarkers in Newly Diagnosed Type 1 Diabetes
This study looks at signs of acute organ injury in children newly diagnosed with type 1 diabetes. It aims to understand how the body reacts to diabetes and its treatment, which could help improve care for kids like yours.
Thessaloniki, Central MakedoniaAges 2–16 - NCT07482137Recruiting
Electroacupuncture for diabetic foot wounds
This trial tests whether electroacupuncture at a specific point (ST-36) can help heal diabetic foot ulcers. It may be an option for people with diabetic foot sores that have not healed well.
Nanjing, JiangsuAges 18–75 - NCT07487467Recruiting
Stem cell therapy for type 2 diabetes
This trial tests using your own fat stem cells to help control blood sugar in type 2 diabetes. It might help if you have had diabetes for less than 10 years and are not on insulin.
São Jose Do Rio Preto, São PauloAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.