Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06864936Recruiting
Eye scan study for ublituximab in multiple sclerosis
This study uses a special eye scan (OCT) to see how well the MS medication ublituximab works. It compares people starting ublituximab to those on other stable MS treatments, to find better ways to measure treatment success.
Baltimore, MarylandAges 18–65 - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT06866483Recruiting
Online screening for undiagnosed myasthenia gravis
This study tests a new online screening tool to find people who might have undiagnosed myasthenia gravis (a muscle-weakness condition). You answer questions about your symptoms and get more information if the tool suggests you might need to talk to a doctor.
Evanston, IllinoisAges 18 years+ - NCT06866652Recruiting
Why Am I Short of Breath? A Study in Myasthenia Gravis
This study looks at why people with myasthenia gravis (MG) feel short of breath. It aims to understand breathing problems that happen in daily life, even when MG seems stable.
ParisAges 18 years+ - NCT06866873Recruiting
CAR-T cell therapy for kids with ALL or lymphoma
This trial tests a special immune cell treatment (CAR-T cells) for children whose leukemia or lymphoma has come back or not responded to at least two prior treatments. The goal is to see if these cells can find and destroy the cancer.
Hong KongAges 1–17 - NCT06867289Recruiting
Nasal sedation study for children during brain MRI
This trial tests a nasal spray sedative (dexmedetomidine) to help children stay calm during a brain MRI. It may be an option if your child struggles with the scan due to age or cooperation issues.
MetzAges 1–18 - NCT06867536RecruitingPhase 2
Radiation plus glofitamab for relapsed large B-cell lymphoma with large tumors
This trial tests whether combining a short course of radiation with a targeted antibody drug (glofitamab) can help people with aggressive large B-cell lymphoma that came back after treatment, especially if they have bulky tumors. It aims to find a new option for hard-to-treat cases.
Wuhan, HubeiAges 18–75 - NCT06867991RecruitingPhase 3
Combination therapy for autoimmune encephalitis
This study tests if combining two medications (a B-cell depleting drug and daratumumab) can help people with autoimmune encephalitis who haven't improved with standard treatments.
Zhengzhou, HenanAges 12 years+ - NCT06868641Recruiting
Study for people stopping long-acting injectable PrEP
This study follows people who are stopping long-acting injectable PrEP (cabotegravir or lenacapavir). It checks how long the drug stays in your body and helps make sure you stay protected during that time. You'll do monthly video visits, mail in blood samples, and fill out short surveys.
New York, New YorkAges 18 years+ - NCT06869551RecruitingPhase 3
Testing a New Drug for Juvenile Psoriatic Arthritis
This study tests an investigational drug called Deucravacitinib to see if it can safely and effectively treat Juvenile Psoriatic Arthritis in children. You may be able to join if standard treatments haven't helped enough.
Lancaster, CaliforniaAges 5–17 - NCT06870045Recruiting
Walking ability test in children with JIA
This study looks at how well children with JIA (arthritis in one knee) can walk and balance, using a simple test called the Dynamic Gait Index. It aims to find a better way to measure walking problems in kids with JIA.
Istanbul, TurkeyAges 8–16 - NCT06871176Recruiting
New PET/MR scan vs standard imaging for multiple myeloma
This trial compares a new type of PET/MR scan (using a radioactive tracer called Ga-68 PentixaFor) with standard imaging to see if it can better detect multiple myeloma at diagnosis and during follow-up. It may help improve staging and treatment planning.
Toronto, OntarioAges 18 years+ - NCT06872294Recruiting
Predicting IVF success with AI
This study looks at factors that might predict success in IVF. If you're under 43, using fresh semen, and have no major uterine or genetic issues, this trial may help researchers learn what leads to a better chance of pregnancy.
Pavia, PaviaAges 18–43 - NCT06872996Recruiting
Do food prick test results change over time?
This study checks whether the shelf life of food extracts used in skin prick tests affects how consistent the results are. It may help make food allergy testing more reliable for people like you.
OrléansAges 18 years+ - NCT06873308Recruiting
Infection activity in travelers and migrants with chronic schistosomiasis
This trial looks at how active a long-term schistosomiasis infection is in travelers and migrants. It aims to better understand the infection to help guide treatment.
AntwerpAges 5 years+ - NCT06874608Recruiting
Does an exclusion diet help juvenile arthritis?
This study tests if removing certain foods can improve arthritis symptoms in children aged 6 to 17. It may be an option if current medicines are not working well or if you want to explore dietary changes.
FlorenceAges 6–18 - NCT06874946RecruitingPhase 1/Phase 2
Nanobody-based CAR-T cells for relapsed T-cell leukemia or lymphoma
This trial tests a new treatment using your own immune cells (called CAR-T cells) that are reprogrammed to find and destroy T-cell leukemia or lymphoma cells that have the CD5 protein. It may be an option if your cancer has come back or hasn't responded to other treatments.
Beijing, Beijing MunicipalityAges 3–70 - NCT06875063RecruitingPhase 1
CAR-T cell therapy for CD19-positive relapsed B-cell lymphoma
This trial tests a new CAR-T cell therapy (a type of immune cell treatment) for patients with a specific kind of B-cell lymphoma that has come back or not responded to previous therapy. The treatment targets a protein called CD19 on the cancer cells to help your immune system fight the lymphoma.
Xiamen, FujianAges 18–70 - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06875167Recruiting
Automated insulin therapy for kids 2-6 with type 1 diabetes
This study tests a semi-automated insulin pump system in very young children (ages 2–6) with type 1 diabetes. It aims to see if the device improves quality of life and blood sugar control.
Nice, FranceAges 2–6 - NCT06875960RecruitingPhase 4
Continuing deucravacitinib for people with lupus
This study lets people who have already finished a previous trial of deucravacitinib continue taking the medicine. It is for adults with lupus, including skin-only forms of the disease, to see if long-term treatment remains safe and helpful.
Farmington, ConnecticutAges 18–75 - NCT06875908Recruiting
Turkish sleep survey test for multiple sclerosis
This study tests a Turkish-language sleep survey for people with multiple sclerosis. It aims to see if the survey is a reliable way to measure sleep problems in MS patients.
Bağcılar, IstanbulAges 18–65 - NCT06876662RecruitingPhase 4
Continuing pirtobrutinib for CLL and lymphoma patients
This trial continues to give pirtobrutinib to people with chronic lymphocytic leukemia or certain other lymphomas who were already in a previous study with this drug. It helps researchers keep track of long-term safety and how well the drug works over time.
Miami, FloridaAges 18 years+ - NCT06876207Recruiting
Real-world study of Control-IQ in teens with type 1 diabetes who exercise regularly
This study observes how well the Control-IQ insulin pump system works for teenagers with type 1 diabetes who exercise at least twice a week. It aims to see if the technology is safe and effective during regular physical activity.
Messina, ItalyAges Up to 20 years
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.