Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT04712539RecruitingPhase 2
Baloxavir and oseltamivir for severe flu in immune-compromised people
This trial tests whether two flu medicines—baloxavir and oseltamivir—work better to treat influenza in people with weakened immune systems (like transplant or blood cancer patients). It may help reduce severe complications, especially when flu affects the lungs or is at high risk to do so.
Houston, TexasAges 12 years+ - NCT04725916Recruiting
Study of water exposure and drain-related risks after certain surgeries
This trial looks at how using water (like showers) affects risks related to surgical drains after specific cosmetic or reconstructive procedures. Your results may help improve post-surgery safety guidance for patients who go home with drains.
Danville, PennsylvaniaAges 18 years+ - NCT04735081Enrolling by invitation
Bed rest vs early getting up for spine bone infection
This study compares standard prolonged bed rest with starting to get up earlier in people with an infection of the spine bones and discs. It aims to see which approach is safer and leads to better recovery.
Ages 18 years+ - NCT04746183RecruitingPhase 1/Phase 2
Early trial testing treatments for COVID-19 in the first days
This early-stage study tests COVID-19 treatments in people who have recently developed symptoms and who test positive for the virus. It aims to find safer, more effective options for preventing worsening disease, especially in higher-risk groups.
Cape TownAges 18 years+ - NCT04713787RecruitingPhase 2
Test higher doses of oxfendazole against single-dose albendazole
This trial studies which dose of oxfendazole works best and is safest for treating a specific intestinal worm infection in adults. It compares different oxfendazole doses to one standard dose of albendazole, and uses stool and blood testing over about 4–6 weeks.
Santa Clara, MaynasAges 18–65 - NCT04700579Recruiting
Study lung changes before and after treatment for active TB
This study looks at changes in the lungs and immune system before TB treatment and again after treatment. By sampling lung fluid and comparing it over time, researchers hope to learn signatures that reflect how TB responds to care.
Cape Town, Western CapeAges 18–60 - NCT04704999RecruitingPhase 4
Testing the right tafenoquine dose for malaria prevention
This study tests the best dose of tafenoquine to treat people with symptoms from a malaria type called P. vivax and to help prevent it from coming back. You may be eligible if you recently had fever and meet specific blood and safety checks, especially G6PD level.
Siem ReapAges 2 years+ - NCT04743609Recruiting
Studying RSV illness impact in babies with ear or lung symptoms
This study looks at how RSV (a common virus that can affect breathing) leads to illness in young children who come to the doctor with ear infections and/or breathing symptoms. It may help doctors better understand the “burden” RSV causes in both home/outpatient and hospital settings.
CréteilAges 1 day–2 years - NCT04759001RecruitingPhase 1/Phase 2
Fecal treatment to clear gut bacteria resistant to antibiotics
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
RomeAges 18–90 - NCT04691622RecruitingPhase 1
Treat chronic norovirus using donor immune cells
This Phase 1 study tests whether giving immune cells made from a donor can help children and adults with long-lasting (chronic) norovirus infection. It’s aimed at people whose immune system is weakened after a stem cell transplant, solid organ transplant, or due to primary immune problems.
Washington D.C., District of ColumbiaAges 3 months–80 years - NCT04705766Enrolling by invitation
Study kidney injury after recent COVID infection
This study looks at how COVID can affect the kidneys soon after infection. You may be able to participate if you recently tested positive for COVID and have not had kidney replacement treatments.
San Francisco, CaliforniaAges 18 years+ - NCT04736732Recruiting
Post-COVID research clinic for adults in Quebec
This study invites adults in Quebec to complete questionnaires and possibly follow-up checks about past COVID-19 infection or symptoms. It may help researchers better understand ongoing effects after COVID, or compare people with different COVID test histories.
Montreal, QuebecAges 18–100 - NCT04751396Recruiting
Melanoma education for people with autoimmune conditions
This trial tests an educational tool to help people with melanoma and pre-existing autoimmune disease understand immune checkpoint inhibitor treatment. It aims to support you and your care team with information that can help you make decisions and feel more prepared.
Houston, TexasAges 18 years+ - NCT03720860Recruiting
Study inflammatory signals in sudden kidney injury in ICU
This study looks at substances related to inflammation to better understand sudden kidney problems in people who are very sick in the ICU. It may help improve how kidney injury is predicted and treated after severe illness or major events.
Uppsala, Uppsala CountyAges 18 years+ - NCT04629053Recruiting
Study of fever causes and outcomes in rural clinics
This study looks at why people develop fever and what outcomes they have after they are seen in rural health facilities. It may help improve how clinics recognize and manage fever illnesses.
DhakaAges 4 weeks+ - NCT04647656Recruiting
Hyperbaric oxygen for lingering post-COVID brain fog
This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve long-lasting post-COVID problems with thinking and memory. It may help if your brain symptoms have lasted at least 3 months and affect your daily life.
ẔerifinAges 18 years+ - NCT04665037RecruitingPhase 2
Posaconazole study for infants under 2 with serious fungal infection
This trial tests whether posaconazole, given through a vein or by mouth, can treat invasive fungal infections in children under 2 years old. It may help improve outcomes for infants with hard-to-treat fungal disease.
San Diego, CaliforniaAges 1 day–2 years - NCT04604730Recruiting
Testing a protective stoma after bowel reconnection for infection
This study looks at whether creating a temporary “protective stoma” (an opening that diverts stool) after reconnecting the bowel can reduce complications for people with severe abdominal infection from a perforated diverticulitis. It’s for adults who had surgery to reconnect their colon right away.
Beauvais, BeauvaisAges 18 years+ - NCT04597437RecruitingPhase 2
Zanamivir for dengue that causes warning signs
This Phase 2 study tests whether zanamivir given through a vein can improve outcomes in people with dengue infection who have warning signs. It may help by reducing the body problems dengue can cause in blood vessels and fluid balance.
Barranquilla, AtlánticoAges 7 years+ - NCT04664179RecruitingPhase 1
EBV immune-cell treatment for EBV-positive lymphoma
This Phase 1 study tests an immune-cell therapy made to recognize EBV (a common virus) in people whose lymphoma contains EBV. It may help control EBV-driven cancers, especially when standard treatment isn’t working or can’t be used.
Houston, TexasAges Any age - NCT04663152Recruiting
Study support to help you stay on treatment
This study tests integrated support that includes counseling, help with following your treatment plan, and research activities to improve treatment adherence. You may be a good match if you live in Miami-Dade and meet the viral load requirement.
Miami, FloridaAges 18 years+ - NCT04664556Recruiting
Study of severe pneumococcal infections in children
This study tracks cases of invasive pneumococcal disease (a serious infection) in children and newborns. It may help clinicians better understand how these infections happen and guide future prevention and treatment.
CréteilAges 1 day–18 years - NCT04652115RecruitingPhase 2
Defibrotide for severe COVID-19 in adults
This trial tests defibrotide to see if it improves outcomes in people hospitalized with severe COVID-19. You may be considered if you have confirmed infection, abnormal chest imaging, and meet specific severity and safety requirements.
Boston, MassachusettsAges 18–100 - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.