Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,175 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2361
- Phase 4321
- Phase 1292
- Phase 3286
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California237
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,175 total
- NCT05035342RecruitingPhase 3
Fecal transplant to clear resistant gut bacteria
This Phase 3 study tests whether a fecal microbiota transplant (FMT) can eliminate hard-to-treat bacteria in the gut, such as ESBL or carbapenem-resistant bacteria. If it works, it may reduce future infections and antibiotic-resistant illness.
ClichyAges 18–105 - NCT05036707RecruitingPhase 1/Phase 2
Study how tick bites change immune responses
This study looks at how a person’s immune system responds after exposure to Ixodes (black-legged) tick bites. It aims to better understand the body’s early immune reaction after tick exposure, using blood tests and small skin samples.
Bethesda, MarylandAges 18–99 - NCT05041140Recruiting
Xenon MRI test for lung problems after stem cell transplant
This study uses a special MRI test with xenon gas to look at lung function in adults who had a stem cell transplant and now have breathing-related complications. It may help doctors measure lung impairment more clearly and track changes over time.
Houston, TexasAges 18 years+ - NCT05041907RecruitingPhase 2
Testing an antiviral’s effects in early COVID-19
This trial looks at how well an antiviral works in the body when started early in people with COVID-19 symptoms. You may be able to join if you’re an otherwise healthy adult with confirmed infection and symptoms for less than 4 days.
Minas GeraisAges 18–60 - NCT05041556Recruiting
Study of RTS,S malaria vaccine evidence in local areas
This study checks how well evidence about the RTS,S/AS01 malaria vaccine helps inform health policy. You may be included if you live in a specific local area and your child is the right age for the vaccine schedule, and you agree to participate.
KintampoAges 6 months–4.9 years - NCT05044403Recruiting
Hemoperfusion for severe sepsis causing multiple organ failure
This study tests whether a blood-filter treatment called hemoperfusion can help critically ill people with sepsis that is not responding to standard shock treatment and is affecting multiple organs. It aims to improve recovery when infections are controlled and inflammation markers are very high.
Castellon, CastellónAges 18–80 - NCT05043116RecruitingPhase 2
Vitamin D for preventing asthma-like flare-ups in young children
This study tests whether a high-dose vitamin D supplement can help preschool children have fewer acute asthma-like symptoms (coughing, wheezing, or trouble breathing) that require hospital care. It may help by supporting the immune and airway system, but you can only join if the child meets several safety and treatment criteria.
Gentofte Municipality, GentofteAges 1 year–5.9 years - NCT05045612RecruitingPhase 4
Antibiotics for certain viral lung infections in hospitalized adults
This trial studies whether giving antibiotics affects recovery in adults hospitalized with moderately severe infections caused by specific viruses (influenza, parainfluenza, RSV, or hMPV). It may help show when antibiotics are helpful or unnecessary for viral airway illness.
BergenAges 18 years+ - NCT05044962Recruiting
Study birth control timing in HIV, using blood tests
This study looks at how well HIV treatment (ART) and a hormonal birth control method (DMPA shot or implant) work together, using small blood samples. It may help ensure safer, more effective HIV care and contraception for young women.
Eldoret, KenyaAges 15–24 - NCT05051098Recruiting
Registry for people with hepatitis B infection
This study is a registry, meaning it collects health information from people living with hepatitis B rather than giving a new treatment. It may help researchers better understand different hepatitis B groups and outcomes over time.
HanoverAges 18 years+ - NCT05054257RecruitingPhase 1
CAR T19 for hard-to-treat blood cancers that have CD19
This Phase 1 study tests CAR T cells designed to attack cancer cells that carry a marker called CD19. It’s for adults with certain relapsed or treatment-resistant B-cell leukemias (ALL) or lymphomas (NHL) where other treatments may not have worked.
PragueAges 18–80 - NCT05057611Recruiting
Tested blood-pressure rescue strategy using skin refill time
This study looks at a specific resuscitation (rescue) approach for adults in septic shock, using a bedside skin test called capillary refill time. If you qualify, the goal is to see whether this approach better stabilizes your body and improves outcomes.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05061329Recruiting
Learn how the nose’s microbes relate to health and disease
This study explores the tiny living organisms (microbes) in your nose and how they may be linked to health problems. It may help researchers better understand disease triggers and potential new prevention or treatment ideas.
Holstebro, Central JutlandAges 18 years+ - NCT05075252Recruiting
Testing whether contamination level matters during laparoscopic appendicitis surgery
This study looks at appendicitis patients having laparoscopic surgery and tests whether the amount of contamination found during surgery affects outcomes. It may help surgeons choose the best way to clean the abdomen during the operation.
MilanAges 18–69 - NCT05076760RecruitingPhase 1
Study of a cancer-killing virus with standard treatments
This Phase 1 trial tests MEM-288, an oncolytic (cancer-killing) virus, either alone or combined with standard cancer medicines, in people with advanced solid tumors. It’s designed to see how the treatment works and how safe it is in different cancer types and after specific prior therapies.
Tampa, FloridaAges 18 years+ - NCT05078957Recruiting
Study gut microbiome in older adults with well-controlled HIV
This trial studies how the bacteria in your gut (“microbiome”) relate to frailty (weakness/low physical resilience) in people with HIV who are stably doing well on treatment. It may help researchers understand why some people become frail and how the gut may play a role.
MarseilleAges 55 years+ - NCT05079711Recruiting
Compare a vaginal yeast test for women with symptoms
This study compares how well a new vaginal yeast (Candida) test matches a standard yeast culture test. It may help clinicians choose the most accurate, convenient way to tell whether vaginal symptoms are caused by yeast.
Fort Bragg, North CarolinaAges 18 years+ - NCT05081401RecruitingPhase 3
All-oral shorter treatment for rifampicin-resistant TB
This Phase 3 trial tests a shorter, all-pill (oral) treatment plan for people with rifampicin-resistant pulmonary tuberculosis. It aims to improve treatment while reducing the burden of therapy, using a plan tailored to the individual.
Guiyang, GuizhouAges 16–75 - NCT05086692RecruitingPhase 1/Phase 2
Beta-only IL-2 therapy for advanced solid tumors
This Phase 1/2 study tests a beta-only version of IL-2, an immune-stimulating treatment, to shrink or control advanced or metastatic solid tumors. It’s mainly designed to check safety and to see if it can help patients by improving tumor response.
San Diego, CaliforniaAges 18 years+ - NCT05093075RecruitingPhase 2
Plasma exchange for ICU patients with severe septic shock
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Calgary, AlbertaAges 16 years+ - NCT05094570RecruitingPhase 4
Dupilumab for nasal polyps with staph bacteria
This trial studies whether dupilumab (an injection) can reduce staph bacteria in the nose and make the nose’s microbes more diverse in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). If you already have a plan to start dupilumab as standard care, the study may help doctors better understand why it works.
Charlottesville, VirginiaAges 18–65 - NCT05100095RecruitingPhase 2
Radiation schedule study for Merkel cell skin cancer
This Phase 2 trial tests a specific radiation timing/dose schedule for Merkel cell carcinoma (MCC), a rare and aggressive skin cancer. It may help by improving control of the cancer after surgery, especially in higher-risk cases (like lymph nodes).
Houston, TexasAges 18 years+ - NCT05108818RecruitingPhase 4
Study immune responses after an flu shot in healthy adults
This study gives you a flu vaccine and measures how your immune system reacts, including both “blood immunity” and “cell immunity.” It’s for healthy adults and mainly aims to better understand how well flu vaccines work in people without major health issues.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05117125Recruiting
Testing for markers in early ventilator lung infections
This study looks at changes (biomarkers) in the blood or other samples from people on a breathing machine. It may help doctors detect ventilator-associated pneumonia earlier and tailor treatment sooner.
DrammenAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,175 recruiting infectious disease studies from the U.S. registry right now, out of 7,076 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.