Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,175 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2361
- Phase 4321
- Phase 1292
- Phase 3286
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California237
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,175 total
- NCT05672927RecruitingPhase 4
Comparing HPV vaccine schedules: 2 doses vs 3 doses
This study compares how well your immune system responds to an HPV vaccine given as either 2 doses or 3 doses in people ages 27–45 who have never had the HPV vaccine. It may help improve HPV prevention strategies and guide the best dose schedule for adults.
Galveston, TexasAges 27–45 - NCT05674175RecruitingPhase 1/Phase 2
Test two engineered immune cell treatments for B-cell leukemia
This trial tests a combination of two different engineered immune cell therapies to treat B-ALL (a leukemia). It’s designed for young people whose disease has come back, is hard to treat, or didn’t respond well to similar cell therapies.
Philadelphia, PennsylvaniaAges Up to 29 years - NCT05674656RecruitingPhase 1/Phase 2
Testing dolutegravir and rilpivirine in HIV-positive children
This study checks how safe and well two HIV medicines work in children ages 6 to under 12. It also measures drug levels in the body to guide dosing and watch for side effects.
Long Beach, CaliforniaAges 6–12 - NCT05674643Recruiting
Gastric testing during children’s surgery
This trial studies how the stomach is working in children around the time of surgery. It may help improve how doctors assess and manage stomach function to make surgery safer and more comfortable.
Boston, MassachusettsAges 2–18 - NCT05676476Recruiting
Tested extra blood-pressure control to extend pregnancy in preeclampsia
This trial studies whether using specific blood-pressure medicines can help people with non-severe preeclampsia stay pregnant longer. It aims to improve outcomes by treating blood pressure early while monitoring you and the baby closely.
Birmingham, AlabamaAges 14–49 - NCT05678621RecruitingPhase 2/Phase 3
Testing stopping or extending immune treatment to prevent infections
This trial studies whether people with certain blood cancers can safely stop their immune support medicine (immunoglobulin, also called Ig) or whether they should continue. It also tests antibiotic prevention strategies to reduce the risk of serious infections.
Garran, Australian Capital TerritoryAges 18 years+ - NCT05678556Recruiting
Relationship education to help prevent HIV in gay and bisexual men
This trial tests a relationship education program to help reduce HIV risk by supporting safer sex choices. It is for people who are currently at higher risk and are HIV-negative.
Chicago, IllinoisAges 16–34 - NCT05681442RecruitingPhase 4
Antibiotics given in different ways for hospital sepsis
This study tests whether giving certain antibiotics intermittently versus continuously, along with a second antibiotic, works better for hospital-acquired sepsis. It may help doctors choose the most effective way to control serious infections.
AmiensAges 18 years+ - NCT05681962Recruiting
Improving breathing support during flexible bronchoscopy
This trial studies how to give oxygen and breathing support during a flexible bronchoscopy (a camera test through the airways). It may help make the procedure safer and more comfortable by refining the way oxygen is managed during the test.
CatanzaroAges 18 years+ - NCT05685628Recruiting
Test cinnamon dressing for smell and comfort of wounds
This study checks whether a cinnamon anti-odor dressing improves quality of life for adults with very smelly wounds. Researchers will compare how the dressing affects comfort and smell, and how well patients can live day to day while treating the wound.
Vaux-le-Pénil, FranceAges 18 years+ - NCT05686759RecruitingPhase 3
Tested IV Hepabig in liver-transplant patients with hepatitis B
This Phase 3 study checks whether an undiluted IV infusion of I.V.-Hepabig inj is safe and works to help prevent hepatitis B from coming back after a liver transplant. It is mainly for adults who had a hepatitis B–related liver transplant and already received Hepabig regularly.
Goyang-si, Gyeonggi-doAges 18–64 - NCT05688592Recruiting
Testing PET-CT scans for invasive fungal infection
This trial checks whether a PET-CT scan using a small amount of tracer (FDG) can help doctors better identify invasive fungal infections inside the body. It may be useful for guiding diagnosis when standard information is unclear.
Majadahonda, MadriidAges 18 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05689281Recruiting
PrEP support for trans women in New Orleans
This study aims to help more trans women (and other women who were assigned male at birth) use or restart PrEP, a medication that helps prevent HIV. You may be eligible if you are HIV-uninfected, live in the New Orleans area, and can do regular follow-up visits.
New Orleans, LouisianaAges 18 years+ - NCT05690841RecruitingPhase 3
Medication campaign to eliminate malaria in nearby villages
This Phase 3 trial tests whether giving malaria medicine to people in high-risk households (a “mass drug administration” campaign) can stop local relapses and eliminate vivax malaria. If you live close to a recent malaria case, you may be offered a preventive dose, based on age and medical safety checks.
IquitosAges Any age - NCT05691348Recruiting
Same-day surgery for uncomplicated acute appendicitis
This trial studies whether removing an uncomplicated appendix in one day (without an overnight hospital stay) is safe and practical. It may help patients recover faster at home, if they meet the trial’s safety requirements.
Nice, Alpes MaritimesAges 15–74 - NCT05692011Recruiting
Testing a blood-filter treatment in children with early sepsis
This trial looks at whether a blood-filter treatment (called “AN69ST Verse PS” using a hemofilter) can help children with early, serious sepsis and poor circulation or organ problems. It may help stabilize the body faster, but eligibility is limited to certain sepsis situations and recent timing.
Shanghai, Shanghai MunicipalityAges 4 weeks–28 years - NCT05694988Recruiting
Filter blood to reduce inflammation in acute pancreatitis
This trial tests whether using blood “filters” plus high-volume fluid filtration can improve outcomes in adults with acute pancreatitis without infection. It aims to remove inflammatory substances from the blood early, while ensuring you’re stable enough for several hours of treatment.
MoscowAges 18–75 - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT05705024RecruitingPhase 2
Eye drops/treatment to heal stubborn cornea surface damage
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
Chicago, IllinoisAges 18 years+ - NCT05706116RecruitingPhase 1
Study gives worm eggs by mouth to healthy adults
This Phase 1 trial tests how safe and tolerated orally taken Trichuris trichiura (a type of intestinal worm) eggs are in healthy adults. It aims to help researchers understand early safety and study setup before any future treatments.
Washington D.C., District of ColumbiaAges 18–45 - NCT05709028RecruitingPhase 3
Fosfomycin for drug-resistant bladder infections in children
This trial tests whether fosfomycin works better than the usual treatment for children with urine infections caused by antibiotic-resistant germs. It may help by using an antibiotic choice that can still work when common oral options may fail.
Sydney, New South WalesAges 6 months–17 years - NCT05711446Recruiting
Studying repeat urine leaks and bladder infections after kidney transplant
This study looks at how often kidney transplant patients get bladder infections after transplant, especially around routine follow-up visits. It may help the clinic find ways to lower infection risk after transplant.
New York, New YorkAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,175 recruiting infectious disease studies from the U.S. registry right now, out of 7,076 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.