Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,223 recruiting studies in this area right now.
By phase
- Not applicable2,755
- Phase 2121
- Phase 4117
- Phase 187
- Phase 383
- Phase 1/Phase 238
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries154
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development38
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California168
- Texas102
- New York85
- Florida80
- Massachusetts58
- Illinois57
- Ohio52
- Pennsylvania51
- Minnesota46
- Maryland42
Recruiting studies3,223 total
- NCT04957355Recruiting
NMES therapy to improve balance and reduce falls after stroke
This trial tests whether NMES (a small electrical stimulation you feel on the skin) can improve balance and lower fall risk in people with stroke-related weakness. It may help you walk more steadily and safely, while the study measures balance and fall-related outcomes.
Chicago, IllinoisAges 18–90 - NCT05224765Enrolling by invitation
Lowering repeat ER visits after injury in older adults
This trial looks at ways to help people 60 and older have fewer repeat ER or hospital admissions after an injury. You may be a candidate if this is your first (main) hospital admission for a traumatic injury and your care team confirms the study’s specific injury admission type.
Dallas, TexasAges 60–100 - NCT05054335Recruiting
Testing personalized walking models for pelvic sarcoma surgery rehab
This study uses personalized computer models and movement measurements (often with MRI) to improve how surgery and physical rehab plans are tailored after pelvic sarcoma surgery. It aims to better understand walking and movement patterns so rehabilitation can be more effective.
Houston, TexasAges 18 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT04851509Recruiting
Testing a special screw-locking nail for hip fractures
This trial studies a specific way of fixing certain hip (upper thigh) fractures using a metal nail with locking screws. It may help improve how well fractures heal and how stable the repair is.
New Westminster, British ColumbiaAges 18 years+ - NCT04933149Enrolling by invitationPhase 4
Ketamine infusion for nerve pain after shoulder nerve injuries
This trial tests whether a ketamine infusion can reduce nerve-related pain after traumatic brachial plexus (shoulder/arm nerve) injuries. It specifically targets people with pain caused by nerve damage who are scheduled for surgery to repair the nerve.
Rochester, MinnesotaAges 18 years+ - NCT04936789Recruiting
Testing a new arm prosthesis with sensors in one arm
This study checks whether a new sensor-enabled prosthesis for people with a lower-arm (transradial) amputation can be safely fitted and used. It may help improve how well a prosthesis can read muscle signals to control a hand/arm replacement.
GlasgowAges 18–65 - NCT04839497RecruitingPhase 2
Safety and benefit of injecting fibroblast cells in leg amputees’ skin
This Phase 2 study tests whether injecting a patient’s own (autologous) fibroblast cells into the end of a transtibial (below-knee) amputation is safe and may improve outcomes. You may qualify if you have a certain type of prosthesis timing and healthy skin on the stump, and you can follow frequent visit and wound-care instructions.
Baltimore, MarylandAges 18–75 - NCT04715139Recruiting
Testing safety of specific foot and ankle implants
This study follows people who get certain Arthrex foot and ankle implants to check how safely they heal and work over time. It may help your care team by adding long-term information about these devices.
Sacramento, CaliforniaAges 2 years+ - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT05851898RecruitingPhase 4
Tested medicine to prevent depression after hip or leg fractures
This trial studies whether a type of antidepressant medicine (a serotonin–norepinephrine reuptake inhibitor) can prevent depression after a lower-extremity fragility fracture that was treated with surgery. It’s mainly for older adults, and aims to see if starting this medicine early reduces later depression symptoms.
Winston-Salem, North CarolinaAges 65 years+ - NCT05195697Recruiting
Study of outcomes for adults needing urgent surgery
This study looks at what factors affect outcomes for adults admitted for urgent (acute) surgical care at Skåne University Hospital. It may help the hospital improve care and understand which patients are at higher or lower risk.
Malmö, Skåne CountyAges 18 years+ - NCT05615844RecruitingPhase 3
Antibiotic beads versus negative pressure dressing for severe leg fractures
This Phase 3 study compares two ways to help heal a severe open tibia (shin bone) fracture and prevent complications like infection. If you qualify, you may receive antibiotic beads or a negative pressure wound therapy dressing after urgent wound cleaning.
Chandler, ArizonaAges 18 years+ - NCT03752034Recruiting
Muscle fragments after rotator cuff surgery to improve shoulder function
This study looks at whether using “muscle fiber fragments” during/after rotator cuff repair can help your shoulder work better. It targets people with a small tear in one shoulder who can follow the post-surgery follow-up plan.
Winston-Salem, North CarolinaAges 40–80 - NCT03935295RecruitingPhase 4
Dysport with a brace for teens with specific scoliosis curves
This trial studies whether adding Dysport (a botulinum toxin shot) to standard bracing can improve scoliosis in teens. It’s mainly for certain curve patterns and requires careful brace follow-through.
Baltimore, MarylandAges 10–16 - NCT05484635Recruiting
Test removing mesh versus leaving it for groin pain
This study compares removing the pre-surgery mesh versus not removing it in people who have long-lasting groin pain after inguinal hernia repair. It may help doctors learn which approach best reduces ongoing pain.
Cleveland, OhioAges 18 years+ - NCT04030650Recruiting
Study of walking expectations on slopes and stairs after limb amputation
This study looks at how people with a leg amputation think about and perform walking on stairs and up/down slopes. It may help researchers understand what supports safer, more confident mobility.
DijonAges 18 years+ - NCT05536609Recruiting
Suture method comparison for injured finger nerves
This study compares two surgical techniques to repair an injured nerve in the finger. It aims to improve how well sensation comes back after a traumatic digital nerve injury.
Stockholm, Stockholm CountyAges 20 years+ - NCT04725201RecruitingPhase 4
IV heparin study after finger or hand reattachment
This study looks at whether giving an IV blood thinner called unfractionated heparin after finger/hand reattachment and restoring blood flow improves healing and safety. If you were accepted into the CEVARMU replant/revascularization program, this trial may be testing a standard-after-surgery medicine approach.
Montreal, QuebecAges 14 years+ - NCT05231343Recruiting
Dual small-plate vs single plate for broken collarbones
This trial compares two surgical plate methods to fix a broken collarbone in the middle part (midshaft). The goal is to see which method works better for healing and function after an acute, fully displaced fracture.
Toronto, OntarioAges 18–65 - NCT05625282Recruiting
Surgery for a floating toe with or without a bone cut
This trial studies how best to repair a “floating toe” using a specific foot surgery approach. It compares whether the repair should be done alone or combined with another bone procedure (a Weil osteotomy).
BarcelonaAges 18 years+ - NCT05601869Recruiting
Testing better footwear options for women with below-knee amputations
This study looks at whether improving what you can use for your prosthesis and footwear can improve comfort, balance, and daily activities. It focuses on women Veterans with below-knee (transtibial) amputations who already use a well-fitting prosthesis.
Minneapolis, MinnesotaAges 18–89 - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT03959904Recruiting
Compare belly-skin closure methods after kidney transplant surgery
This study looks at which abdominal wall (belly) closure technique helps reduce the chance of an incisional hernia after a kidney transplant. If you’re having a kidney transplant, it may help surgeons choose a method that lowers this complication for future patients.
ManchesterAges 18–70
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,223 recruiting trauma studies from the U.S. registry right now, out of 5,129 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.