Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT06889948RecruitingPhase 2
Daratumumab for kidney disease caused by abnormal proteins
This trial tests if daratumumab can help people with a kidney condition called MGRS, where abnormal proteins damage the kidneys. The goal is to see if the drug can reduce protein in the urine and protect kidney function.
HelsinkiAges 18 years+ - NCT06880302Recruiting
Male infertility research for sperm and tissue samples
This trial collects sperm, semen, and testicular tissue samples from men undergoing fertility treatments to build a biobank for research. If you are providing such samples for freezing, you can help advance understanding of male infertility.
Basking Ridge, New JerseyAges Any age - NCT06886321Recruiting
Testing a new non-surgical prostate cancer treatment
This trial tests a new, non-surgical treatment called irreversible electroporation (IRE) for men with early-stage prostate cancer that hasn't spread. It uses short electrical pulses to destroy cancer cells while sparing healthy tissue nearby.
Hong KongAges 40–85 - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45 - NCT06882486Recruiting
Kidney removal after successful immunotherapy for metastatic cancer
This trial is for people with kidney cancer that has spread to other parts of the body, who still have their original kidney tumor. If your cancer has responded very well to immunotherapy (a type of treatment that helps your immune system fight cancer), doctors want to see if removing the kidney tumor now can improve your outcome.
Marseille, Institut Paoli-calmettesAges 18 years+ - NCT06890143RecruitingPhase 3
Dapagliflozin for kids with genetic kidney disease and protein in urine
This trial tests if dapagliflozin, a medication that lowers blood sugar and protects the kidneys, can reduce protein in the urine of children with inherited kidney disease. It may help preserve kidney function when added to standard blood pressure medication.
Shanghai, Shanghai MunicipalityAges 6–18 - NCT06884410Recruiting
Reproducibility of kidney MRI scans on 1.5 Tesla machines
This study checks whether kidney MRI scans give consistent results when repeated. Healthy adults with normal blood pressure and kidney function are needed to help improve MRI techniques for future patients.
AarhusAges 18–70 - NCT06886464RecruitingPhase 2
Preventing kidney injury from strong medications with cilastatin
This study tests whether a medicine called cilastatin can prevent kidney damage caused by certain strong medications. If you are receiving one of these medications and are at risk for kidney injury, this trial may offer protection.
Calgary, AlbertaAges 18 years+ - NCT06889974Recruiting
Timing of kidney treatment in tumor lysis syndrome
This study looks at when to start kidney dialysis for patients in the ICU who develop tumor lysis syndrome (a rapid breakdown of cancer cells after chemotherapy that can harm the kidneys). It aims to find the best timing for this treatment.
AngersAges 18 years+ - NCT06877169Recruiting
Staged heart and kidney transplant study
This study compares two ways of doing a combined heart and kidney transplant. It looks at doing the surgeries in separate stages instead of all at once, to see if that is safer or works better.
Los Angeles, CaliforniaAges 18 years+ - NCT06868927Recruiting
Using MRI to guide treatment for small kidney tumors
This study tests whether MRI scans can help doctors make better decisions about treatment for small kidney tumors. If you have a kidney mass up to 4 cm and are planning surgery, you may be able to join.
Milan, ItaliaAges 18 years+ - NCT06877598Recruiting
Online sexual health clinic for prostate cancer patients
This study tests an online clinic (SHAReClinic) that helps prostate cancer patients and their partners with sexual health and recovery. You can join if you’re in active treatment or recently finished, have internet access, and meet a few health-related requirements.
Vancouver, British ColumbiaAges 18 years+ - NCT06879145RecruitingPhase 2/Phase 3
Study of SHR-A2102 and Adebrelimab for muscle-invasive bladder cancer
This trial tests a combination of two drugs, SHR-A2102 and Adebrelimab, for people with muscle-invasive bladder cancer that hasn't spread. The goal is to see if this treatment can help control the cancer.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06872619Enrolling by invitation
Prostate Cancer Research Registry
This registry collects information from people with prostate cancer to help researchers better understand the disease and improve future treatments.
MünsterAges 45–100 - NCT06878560RecruitingPhase 1/Phase 2
Pig kidney transplant for kidney failure patients
This trial tests a special pig kidney (10 GE Xenokidney) as a transplant option for people with kidney failure who cannot get a human kidney. It aims to offer a life-saving alternative.
Chicago, IllinoisAges 40–70 - NCT06872866RecruitingPhase 1
Study of sildenafil with and without food in healthy men
This study looks at how taking the study drug Hezkue Turbo (sildenafil) with food affects its levels in the body compared to taking it on an empty stomach. Healthy male volunteers aged 20 to 70 can participate.
New York, New YorkAges 20–70 - NCT03093688RecruitingPhase 1/Phase 2
Testing an immune-cell infusion for advanced solid tumors
This trial tests whether adding special immune cells (iNKT cells and CD8+ T cells) given by IV infusion can help treat advanced cancers. It mainly looks at safety first, and also checks whether the treatment can shrink or control cancer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06392737Recruiting
AI-guided MRI vs routine MRI for prostate biopsy
This study tests whether an artificial intelligence tool for MRI can improve the results of targeted prostate biopsy, compared to the usual method. It could help diagnose prostate cancer more accurately with fewer needles.
Beijing, Beijing MunicipalityAges 45–85 - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT06863272RecruitingPhase 1/Phase 2
Study of ifinatamab deruxtecan for advanced prostate cancer
This trial tests a new drug, ifinatamab deruxtecan, either alone or in combination with other treatments, for men with metastatic castrate-resistant prostate cancer that has worsened despite hormone therapy. It aims to see if this approach can help shrink or slow the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06858397RecruitingPhase 1/Phase 2
Study of a new drug for Fabry disease
This study tests a new investigational drug called HM15421/GC1134A for people with Fabry disease. It aims to see if the drug is safe and tolerable, and to learn how well it works. You may be eligible if you have Fabry disease with symptoms, have not had treatment for at least 6 months, and your kidneys are functioning well.
Los Angeles, CaliforniaAges 18 years+ - NCT06868186Recruiting
Robot-assisted surgery for kidney tumors
This trial tests a new robotic system for removing kidney tumors up to 7 cm. It aims to see if the technology helps surgeons perform partial nephrectomy (removing only the tumor) safely and effectively.
Kwangju, Jeollanam-doAges 19–80 - NCT06866262RecruitingPhase 1/Phase 2
Inulin gel with immunotherapy for advanced kidney cancer
This trial tests whether adding an inulin gel to standard immunotherapy (ipilimumab and nivolumab) can help treat kidney cancer that has spread or cannot be removed. It is for people who have not had prior treatment for advanced disease.
Ann Arbor, MichiganAges 18 years+ - NCT06858280RecruitingPhase 3
Patiromer and diet for potassium in dialysis patients
This trial tests if a medication called patiromer, combined with a low-potassium diet, can help manage potassium levels in people on chronic dialysis. The goal is to improve quality of life by allowing a more flexible diet.
Bergamo, BGAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.