Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT05230511RecruitingPhase 2
Bladder wash with LGG probiotic vs saline for nerve bladder
This study tests whether putting a probiotic called LGG into the bladder works better than a saline bladder rinse to help people with a nerve-related bladder problem. It may improve bladder symptoms or reduce bladder infections, compared with standard saline rinses.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05879653RecruitingPhase 2
Pembrolizumab, drug EV, and radiation for bladder cancer
This Phase 2 study tests how well pembrolizumab and an antibody-drug medicine (EV) given with bladder radiation work for non-metastatic bladder cancer that is mostly urothelial. It may help some people control the cancer without it spreading to other organs.
Kobe, HyōgoAges 18 years+ - NCT06553898RecruitingPhase 1
CAR-T cell therapy for hard-to-treat kidney disease
This trial tests a new CAR-T cell treatment for children and adults with steroid-resistant nephrotic syndrome (SRNS), a kidney condition that doesn't get better with standard medicines. The goal is to see if this therapy can help improve kidney function when other treatments have failed.
Hangzhou, ZhejiangAges 2 years+ - NCT06557265RecruitingPhase 1/Phase 2
NKX019 for lupus kidney disease or membranous nephropathy
This trial tests an experimental cell therapy called NKX019 for people with active lupus nephritis (a type of kidney inflammation from lupus) or primary membranous nephropathy (another kidney condition) that hasn't gotten better after standard treatments. It may help if you have tried at least two treatments for lupus kidney disease or one for membranous nephropathy and still have active kidney disease.
Little Rock, ArkansasAges 18–75 - NCT06552169RecruitingPhase 2
Treg cell therapy to lower anti-rejection meds after kidney transplant
This trial tests whether adding a special type of immune cell (Treg cells) to standard therapy can help kidney transplant recipients safely take lower doses of anti-rejection medicines. It is for people who are getting a kidney from a living donor.
Phoenix, ArizonaAges 18–65 - NCT06549465RecruitingPhase 2
Ac-225 rosopatamab for PSMA-positive castration-resistant prostate cancer
This trial tests a radioactive drug (Ac-225 rosopatamab tetraxetan) that targets a protein called PSMA on prostate cancer cells. It is for patients whose cancer has stopped responding to hormone therapy and has spread to other parts of the body.
San Diego, CaliforniaAges 18 years+ - NCT04449991Recruiting
Repeat kidney biopsy in new lupus kidney disease
This study looks at whether doing a planned second kidney biopsy about 12 months later helps doctors understand and guide treatment for people with newly diagnosed lupus nephritis. You may be put on standard lupus-kidney medications, and the main “test” is the repeat biopsy timing.
StockholmAges 18 years+ - NCT06558994Recruiting
Surgery comparison for undescended testicles in children
This study compares two surgical methods for fixing undescended testicles that cannot be felt during a physical exam. The goal is to see which technique leads to better outcomes.
Asyut, EgyptAges Up to 12 years - NCT06563765Enrolling by invitation
PET/CT scan for tracking kidney scarring
This trial uses a special PET/CT scan to look at kidney scarring (fibrosis) in people with chronic kidney disease. It could help doctors monitor kidney damage without needing a biopsy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06563388RecruitingPhase 3
SABR for limited metastatic cancer (ID-COMET trial)
This study tests a precise radiation technique called SABR to treat cancer that has spread to a few spots. It aims to see if this approach can help control the cancer better than usual treatment, especially for lung, prostate, colorectal, or other solid tumors with limited spread.
Buffalo, New YorkAges 1 year+ - NCT06560801RecruitingPhase 4
Dapagliflozin for kidney health after transplant
This trial tests whether taking dapagliflozin (a drug often used for diabetes and heart health) can help improve kidney structure and blood flow in people who received a kidney transplant at least 9 months ago. It may benefit those whose kidney function is stable, regardless of whether they have diabetes.
Erlangen, BavariaAges 18–75 - NCT06561451Recruiting
Comparing two IVF methods for severe sperm shape issues
This trial compares two lab techniques (ICSI alone vs. ICSI with AOA) to see which leads to more live births for couples where the male partner has very abnormal sperm shape (99-100% abnormal). The study focuses on women aged 20-37 who are undergoing fertility treatment.
ShanghaiAges 20–37 - NCT06556407Recruiting
Kidney nerve treatment for high blood pressure in dialysis patients
This trial tests a procedure called renal denervation (using radio waves to calm overactive nerves in the kidney) to see if it helps lower blood pressure in people on dialysis who have resistant high blood pressure.
Erlangen, BavariaAges 18–99 - NCT06565741Recruiting
Laser Comparison for Enlarged Prostate Surgery
This study compares two advanced laser techniques (Moses 2.0 and Thulium fiber laser) for treating enlarged prostates (BPH) that are causing significant urinary problems. The goal is to see if one laser is more effective at removing prostate tissue and improving symptoms with fewer side effects.
Barcelona, BARCELONAAges 40–90 - NCT06551246RecruitingPhase 3
Medicines for daytime wetting in children
This study tests two medicines (solifenacin and mirabegron) alone and together to see which works best for children with daytime wetting. It is for children ages 5 to 14 who still have accidents after trying non-drug treatments.
Aalborg, AalborgAges 5–14 - NCT06559618RecruitingPhase 1
Phage therapy for bladder bacteria in spinal cord injury
This trial tests whether a special virus (bacteriophage) that attacks E. coli bacteria can help control bacteria in the bladder without causing an infection. It's for people with spinal cord injury who use a catheter and have E. coli in their urine but no active infection.
St Louis, MissouriAges 18 years+ - NCT06259799Recruiting
Smart water bottle to help college students drink more
This trial tests whether a smart water bottle that reminds you to drink can help college students who don't drink enough water stay hydrated. You'll use the bottle and an app to track your fluid intake.
Kennesaw, GeorgiaAges 18–35 - NCT03629977Recruiting
Timing dialysis in critically ill ICU patients
This study looks at the best timing for starting kidney support treatment (dialysis) in very sick people in the ICU. It may help improve outcomes by comparing different start times.
StockholmAges 18 years+ - NCT05649943Recruiting
New prostate cancer treatment plus local therapy for metastatic cases
This trial studies whether adding apalutamide to standard hormone therapy (ADT) improves outcomes for men with metastatic hormone-sensitive prostate cancer. Some people may also receive local treatments (like surgery or radiotherapy) to control the prostate and nearby areas.
Milan, LombardyAges 18 years+ - NCT06255223RecruitingPhase 2
Radiation therapy plus immunotherapy for advanced kidney cancer
This trial tests a combination of targeted radiation therapy with a restart of immunotherapy for people whose kidney cancer has grown after prior immunotherapy. It aims to see if radiation can help the immune system fight the cancer again.
Nanjing, JiangsuAges 18–80 - NCT06533644RecruitingPhase 2
SYNC-T therapy study for advanced prostate cancer
This trial tests a new treatment called SYNC-T Therapy (SV-102) for men with metastatic castration-resistant prostate cancer that has progressed after other treatments. The therapy is given directly into a tumor to help your immune system fight the cancer.
Phoenix, ArizonaAges 18 years+ - NCT06545955RecruitingPhase 3
Gene therapy study for high-grade bladder cancer not responding to BCG
This trial tests a gene therapy called nadofaragene firadenovec, given directly into the bladder, either alone or with chemo or immunotherapy. It's for people with high-grade bladder cancer that hasn't gone away after BCG treatment.
Tucson, ArizonaAges 18 years+ - NCT06545942RecruitingPhase 1
Studying MOMA-313 for advanced or metastatic solid tumors
This trial tests a new oral drug, MOMA-313, alone or with another drug (olaparib), in people whose cancer has a specific DNA repair problem (HR-deficient mutation). It aims to see if the drug can shrink tumors or slow their growth.
Goodyear, ArizonaAges 18 years+ - NCT06547398Recruiting
Adaptive radiation therapy for prostate cancer
This trial tests a special type of radiation therapy for prostate cancer that adjusts to small changes in your body. It aims to better target the cancer while reducing side effects.
St Leonards, New South WalesAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.