Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,502 recruiting studies in this area right now.
By phase
- Not applicable2,817
- Phase 2566
- Phase 1365
- Phase 3272
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Chronic Kidney Disease105
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Head and Neck Cancer45
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca31
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California349
- Alabama112
- Arizona104
- Florida96
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,502 total
- NCT07566156RecruitingPhase 3
New drug combination vs. radiation for bladder cancer preservation
This trial tests whether two drugs (enfortumab vedotin and pembrolizumab) work better than radiation with chemotherapy for muscle-invasive bladder cancer. The goal is to treat your cancer while keeping your bladder instead of removing it.
Santa Barbara, CaliforniaAges 18 years+ - NCT07455903RecruitingPhase 2
Hormone therapy before surgery for high-risk prostate cancer
This trial tests whether giving hormone therapy (androgen deprivation therapy) before surgery can improve outcomes for men with high-risk prostate cancer. You will receive a special PSMA PET/CT scan to see how the cancer responds.
Miami, FloridaAges 18 years+ - NCT05958342RecruitingPhase 2
Calcium and vasopressin for bleeding shock after major injury
This trial tests whether giving calcium and vasopressin early can improve outcomes in people with major injury who are at risk for life-threatening bleeding shock. It mainly includes patients who need rapid blood transfusion and likely major surgery to stop bleeding.
Chandler, ArizonaAges 18–90 - NCT07188896RecruitingPhase 2
Immunotherapy combinations for advanced kidney cancer
This trial tests a combination of immunotherapy drugs (fianlimab, cemiplimab, and possibly ipilimumab) compared to another immunotherapy combo (ipilimumab + nivolumab) for people with advanced kidney cancer who have not had previous treatment. The goal is to see which combination works better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06290687RecruitingPhase 2
Partial cystectomy with chemo for bladder cancer
This trial tests whether removing part of the bladder (partial cystectomy) along with standard chemotherapy or immunotherapy before surgery is effective for people with a specific type of bladder cancer that hasn't spread beyond the bladder.
Cleveland, OhioAges 19 years+ - NCT04715191RecruitingPhase 1
CAR T therapy for GPC3-positive pediatric solid tumors
This Phase 1 study tests a customized immune-cell treatment (CAR T cells) made to recognize GPC3, a marker found on some tumors. It’s designed for children and young people whose solid tumors have not been cured by standard treatment and who can safely receive this therapy.
Houston, TexasAges 1–21 - NCT06510374RecruitingPhase 3
Gene therapy vs. observation for intermediate risk bladder cancer
This trial tests a new gene therapy called nadofaragene firadenovec versus just watching and waiting (observation) for people with a specific type of bladder cancer that hasn't grown into the muscle. The goal is to see if the gene therapy can help keep the cancer from coming back.
Mobile, AlabamaAges 18 years+ - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT05610852Recruiting
Surgery through the bladder opening versus focused ultrasound for prostate cancer
This trial compares two ways to treat early prostate cancer: a single small surgery through the bladder versus high-intensity focused ultrasound (HIFU). It aims to see which approach works better while keeping side effects and recovery acceptable.
Cleveland, OhioAges 19 years+ - NCT07114601RecruitingPhase 1
Study of LY4257496 for people with GRPR-positive solid tumors
This trial tests a new drug, LY4257496, in people with certain types of cancer that have a protein called GRPR on their cells. The study aims to see if the drug can help shrink tumors or slow the cancer's growth.
Duarte, CaliforniaAges 18 years+ - NCT07029256Recruiting
Ultrasound-guided biopsy for bladder cancer staging
This trial uses an ultrasound-guided needle biopsy to check if bladder cancer has spread beyond the bladder. It may help doctors stage the cancer more accurately before surgery.
Rochester, MinnesotaAges 18 years+ - NCT07087314RecruitingPhase 2
Study of an injection for nephrotic syndrome in children
This study tests an injection (SG301) that targets a protein called CD38 to help children whose nephrotic syndrome keeps coming back or depends on steroids. The goal is to see if the treatment can reduce relapses and the need for steroids.
Hangzhou, ZhejiangAges 6–18 - NCT07075666Enrolling by invitation
Early detection of prostate cancer in Syrian men
This trial aims to find prostate cancer early in Syrian men living in the middle region of the country. If you join, you'll help doctors learn better ways to screen for the disease, which may lead to earlier and more effective treatment.
HomsAges 40–65 - NCT07060716Recruiting
Blood test to monitor kidney transplant health
This study is testing a blood test that looks for tiny pieces of the donor's DNA in your blood to check how your new kidney is doing. It may help doctors monitor your transplant and spot problems early, possibly without needing a biopsy.
Los Angeles, CaliforniaAges 18 years+ - NCT07069491Recruiting
High blood pressure during dialysis: what causes it?
This study is looking at why some people develop high blood pressure during their dialysis sessions. Your participation could help doctors better manage this condition in the future.
SohagAges 18–70 - NCT06975033Recruiting
Video discharge instructions after prostate surgery
This study tests if watching a short educational video before going home after HoLEP prostate surgery helps patients understand their recovery better. The goal is to see if the video reduces questions or visits to the doctor after surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06966778Recruiting
Oxybutynin to help bladder control after prostate surgery
This trial tests if the medicine Oxybutynin ER (a drug that helps relax the bladder) can help you regain bladder control sooner after robotic prostate surgery. Participants will be randomly assigned to receive either the drug or a placebo for a few weeks after surgery.
TaipeiAges 18 years+ - NCT06910527Recruiting
Testing blood and urine for kidney rejection signs
This study is for people with a kidney transplant who are in the hospital for a biopsy because their doctor suspects rejection. Researchers want to see if a simple blood or urine test can detect rejection, which might make future biopsies less necessary.
RouenAges 18 years+ - NCT06979583Enrolling by invitation
Stent and sheath size and pain after kidney stone surgery
This study compares whether the size of the stent and the sheath used during kidney stone surgery affects how much pain you feel afterward. If you are having a stone removal procedure and will get a stent with a string, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06834321RecruitingPhase 2
Homoharringtonine with hormone therapy before prostate surgery
This trial tests a new combination of a chemotherapy drug (homoharringtonine) and hormone therapy (androgen deprivation) given before surgery to shrink prostate cancer that has spread a little or is advanced. The goal is to see if this approach can help control the cancer better before the prostate is removed.
Nanjing, JiangsuAges 18–85 - NCT06759961Recruiting
Outcomes after kidney transplant for a blood vessel condition
This study looks at outcomes after kidney transplant for a rare blood vessel condition called thrombotic microangiopathy. It aims to learn more about how patients do after transplant at a specific center in Bologna, Italy.
Bologna, BOAges 18 years+ - NCT06781944RecruitingPhase 3
Obinutuzumab vs standard treatment for membranous nephropathy
This trial tests a new antibody drug (obinutuzumab) against a standard treatment (cyclophosphamide plus steroids) for people with a kidney condition called primary membranous nephropathy that causes protein leakage. The goal is to see which treatment better reduces protein loss and protects kidney function.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,502 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,145 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.